Tag: Disease models

Inhibitory effects of bevacizumab on corneal neovascularization and scarring in mice with herpes simplex keratitis

Authors: Zhou Hongwei,  Wang Tongsong,  Zhang Songmei,  Xie Lixin DOI: 10.3760/cma.j.issn.2095-0160.2017.12.007 Published 2017-12-10 Cite as Chin J Exp Ophthalmol, 2017,35(12): 1085-1091. Abstract                               [Download PDF] [Read Full Text] Background Corneal neovascularization and inflammation occur in herpes simplex keratitis (HSK). Aciclovir (ACV) is an antiviral medication which is primarily used for […]

Dynamic observation of ocular surface in ovariectomized cynomolgus monkey

Authors: Li Lei,  Zhang Xiaofeng,  Li Mengmeng,  Que Lijuan,  Li Chang DOI: 10.3760/cma.j.issn.2095-0160.2018.02.008 Published 2018-02-10 Cite as Chin J Exp Ophthalmol, 2018,36(2): 113-118. Abstract                               [Download PDF] [Read Full Text] Objective To investigate the feasibility of ovariectomized cynomolgus monkey as an animal model of postmenopausal dry eye. Methods Six healthy adult […]

Promoting repair effects of chitosan/gelatin electrospinning membrane implantation on rabbit conjunctival injury

Authors: Zheng Yuqiang,  Wang Zhuoshi,  Xu Ling,  Wang Liansong,  He Wei DOI: 10.3760/cma.j.issn.2095-0160.2018.02.006 Published 2018-02-10 Cite as Chin J Exp Ophthalmol, 2018,36(2): 102-106. Abstract                              [Download PDF] [Read Full Text] Objective To investigate the promoting repair effects of chitosan/gelatin electrospinning membrane implantation on conjunctival injury. Methods Chitosan/gelatin electrospinning membrane was prepared […]

Neuroprotective effects of tianmagouteng decoction on retinal ganglion cells in optic nerve crush model

Authors: Li Yujie,  Ma Ke,  Zhang Haijuan,  Wang Haiyan DOI: 10.3760/cma.j.issn.2095-0160.2018.02.004 Published 2018-02-10 Cite as Chin J Exp Ophthalmol, 2018,36(2): 91-95. Abstract                              [Download PDF] [Read Full Text] Objective To investigate the neuroprotective effect and antioxidation mechanism of tianmagouteng decoction on retinal ganglion cells (RGCs) in optic nerve crush model. […]

Protective effects of carnosic acid on retinal ganglion cells in acute ocular hypertension rats model

Authors:  He Liye,  Liang Liang,  Zhu Mengnan,  Xiao Changyi,  Tu Xiaokun DOI: 10.3760/cma.j.issn.2095-0160.2018.04.005 Published 2018-04-10 Cite as Chin J Exp Ophthalmol, 2018,36(4): 254-258. Abstract                               [Download PDF] [Read Full Text] Objective To observe the protective effects of carnosic acid on retinal ganglion cells (RGCs) in acute ocular hypertension rats model. Methods […]