Tag: Epithelial-mesenchymal transition

Regulation and its mechanism of MeCP2 on biological behavior and epithelial-mesenchymal transition of LECs

Authors: Niu Chao,  Wu Zhong,  Huang Yalin,  Zhang Ying,  Wang Yingfei,  Li Xiaohua,  Lu Wenlong DOI: 10.3760/cma.j.issn.2095-0160.2020.01.007 Published 2020-01-10 Cite as Chin J Exp Ophthalmol, 2020,38(01): 32-37. Abstract                               [View PDF]  [Read Full Text]  Objective To investigate the role of methyl-CpG-binding protein 2 (MeCP2) in the regulation […]

In vitro epithelial-mesenchymal transition model for LECs of human posterior capsule opacification

Authors: Yang Baoxia,  Wang Ye,  Zhao Xiaowen,  Liu Ting,  Huang Yusen DOI: 10.3760/cma.j.issn.2095-0160.2016.03.004 Published 2016-03-10 Cite as Chin J Exp Ophthalmol, 2016,34(3): 210-217. Abstract                               [Download PDF] [Read Full Text] Background Epithelial-mesenchymal transition (EMT) is one of the pathogenesis mechanisms of posterior capule opcification (PCO). Studying EMT is of important significance […]

Wnt3a-induced extracellular matrix production and gel contraction in human lens epithelial cells

Authors: Bao Xiuli,  Liu Tingting,  Wang Yanyan,  Li Lin DOI: 10.3760/cma.j.issn.2095-0160.2016.07.005 Published 2016-07-10 Cite as Chin J Exp Ophthalmol, 2016,34(7): 597-601. Abstract                               [Download PDF] [Read Full Text] Background Excessive production, deposition and contraction of extracellular matrix (ECM) of human lens endothelial cells (LECs) is one of […]

Inhibiting effects of Src kinase inhibitor on TGF-β1 induced epithelial-mesenchymal transition of human RPE cells

Authors: He Jianfeng,  Lyu Lixia,  Luo Junjie,  Li Zongyi,  Shen Junhui,  Xu Guotong,  Gao Furong DOI: 10.3760/cma.j.issn.2095-0160.2018.01.002 Published 2018-01-10 Cite as Chin J Exp Ophthalmol, 2018,36(1): 5-11. Abstract                              [Download PDF] [Read Full Text] Objective To investigate the inhibiting effect of CGP77675 (CGP), a Src inhibitor, on epithelial-mesenchymal transition (EMT) of human retinal […]