Authors: Tang Haoqiong, Feng Lixia, Tao Tianchang, Zeng Yige DOI: 10.3760/cma.j.cn115989-20231017-00137 Published 2024-08-10 Cite as Chin J Exp Ophthalmol, 2024, 42(8): 698-704. Abstract [Download PDF] [Read Full Text] Objective To investigate the damage of visual function in the […]
Tag: Mice
Metabolomics study of kidney tissue in a mouse model of oxygen-induced retinopathy
Authors: Dong Lijun, Qi Hui, Yang Yuhang, Mao Xingxing, Zhang Guoming, Zhang Shaochong, Lei Hetian DOI: 10.3760/cma.j.cn115989-20220526-00248 Published 2024-01-10 Cite as Chin J Exp Ophthalmol, 2024, 42(1): 19-28. Abstract [Download PDF] [Read Full Text] Objective To explore the effects of hyperoxic environments […]
Value of virtual operating system for visual behavioral assessment in mice models of visual disease
Authors: Jiao Yang, Shao Zhengbo DOI: 10.3760/cma.j.cn115989-20210524-00315 Published 2023-08-10 Cite as Chin J Exp Ophthalmol, 2023, 41(8): 822-826. Abstract [Download PDF] [Read Full Text] Visual behaviorally operant method is one of the main detections for identifying animal models of visual diseases, which […]
Relationship between regression of the hyaloid vessels and development of retinal vessels in mice
Authors: Qin Jiahui, Guo Yatu, Zhang Wei DOI: 10.3760/cma.j.cn115989-20210409-00241 Published 2023-07-10 Cite as Chin J Exp Ophthalmol, 2023, 41(7): 623-629. Abstract [Download PDF] [Read Full Text] Objective To explore the process of regression of the hyaloid vessels and development of retinal vessels […]
Inhibitory effect of gamma-secretase inhibitor on retinal neovascularization and regulative mechanism of Notch1 signal pathway
Authors: Cheng Zhixing, Xie Jie, Meng Qianli DOI: 10.3760/cma.j.cn115989-20220820-00384 Published 2022-11-10 Cite asChin J Exp Ophthalmol, 2022, 40(11): 1031-1037. Abstract [View PDF] [Read Full Text] Objective To investigate the inhibitory effect and underlying mechanism of gamma-secretase inhibitor blocking Notch1 signaling on […]
Establishment of lens opacity model in Grx2 knockout mice based on CRISPR/cas9 system and the role of Grx2 in the pathogenesis of cataract
·Experimental Research· Establishment of a lens opacity model in Grx2 knockout mice based on the CRISPR/cas9 system and the role of Grx2 in cataract pathogenesis Guo Yong1, Guo Chenjun2, Zhang Jie2, Ning Xiaona2, Chen Xi3, Yan Hong1 1Department of Ophthalmology, Xi’an People’s Hospital, Xi’an Fourth Hospital, Shaanxi Eye Hospital, Xi’an 710004, China; 2Department of Ophthalmology, […]
Advances in rodent models of retinal neovascularization
Authors: Xu Qianhui, Chen Jun, Shao Yi DOI: 10.3760/cma.j.cn115989-20200211-00064 Published 2022-10-10 Cite asChin J Exp Ophthalmol, 2022, 40(10): 996-998. Abstract [View PDF] [Read Full Text] Retinal neovascularization (RNV) originating from retinal blood vessels is one of the main pathological features of many ocular […]
Therapeutic effect of anti-IL-12/IL-23 p40 on experimental autoimmune uveitis and its mechanism
·Experimental Research· Therapeutic effect of anti-IL-12/IL-23 p40 on experimental autoimmune uveitis and associated mechanism Cui Xuexue, Zhang Zhihui, Wu Lingzi, Li Yongtao, Chen Shuang, Chen Nu, Zhang Xiaomin Tianjin Key Laboratory of Retinal Functions and Diseases, Tianjin Branch of National Clinical Research Center for Ocular Disease, Eye Institute and School of Optometry, Tianjin Medical University […]