Author: Guo Kai, Luo Yan, Li Tao, Tian Jingyi, Sun Wei, Lin Shaofen, Tang Shibo DOI: 10.3760/cma.j.issn.2095-0160.2015.09.006 Published 2015-09-10 Cite as Chin J Exp Ophthalmol, 2015,33(9): 794-797. Abstract [Download PDF] [Read Full Text] Background Stem cell transplantation represents a promising treatment option […]
Tag: Mice
In vitro-expansion of induced regulatory T cells and its inhibitory effects on corneal allograft rejection
Authors: Wei Tongxin, Li Guangling, Guo Xuming DOI: 10.3760/cma.j.issn.2095-0160.2015.10.007 Published 2015-10-10 Cite as Chin J Exp Ophthalmol, 2015,33(10): 896-901. Abstract [Download PDF] [Read Full Text] Background Researches showed that CD4+ CD25+ natural regulatory T cells (nTregs) play an important role in maintaining peripheral immune […]
Construction of murine model of TAO by immunification with recombinant extracellular domain of human thyrotropin receptor in cationic liposomes
Authors: Yang Yuli, Luo Qingli, Lyu Hongbin DOI: 10.3760/cma.j.issn.2095-0160.2015.11.004 Published 2015-11-10 Cite as Chin J Exp Ophthalmol, 2015,33(11): 974-980. Abstract [Download PDF] [Read Full Text] Background Thyroid-associated ophthalmopathy (TAO) is a kind of clinically common and incurable ocular disease, and its incidence […]
Establishment of mouse model of orbital diffuse large B cell lymphoma
Authors: Li Shiyun, Sun Fengyuan DOI: 10.3760/cma.j.issn.2095-0160.2015.11.005 Published 2015-11-10 Cite as Chin J Exp Ophthalmol, 2015,33(11): 981-984. Abstract [Download PDF] [Read Full Text] Background Recently, the morbidity of orbital lymphoma increased gradually, and we have made deeper research in pathology, therapy and pathogenesis […]
Analysis of protein expression profiling in a mouse model of oxygen-induced retinopathy
Authors: Qi Chen, Han Qian, Bo Qiyu, Liu Xun, Wang Fei, Zhang Yan, Li Xiaorong DOI: 10.3760/cma.j.issn.2095-0160.2015.12.004 Published 2015-12-10 Cite as Chin J Exp Ophthalmol, 2015,33(12): 1069-1075. Abstract [Download PDF] [Read Full Text] Background Retinal neovascularization (RNV) is one of the major […]
Effects of macrophages and monocyte chemoattractant protein-1 during experimental choroidal neovascularization
Authors: Zhang Shukun, Xie Ping, Yuan Dongqing, Liu Qinghuai DOI: 10.3760/cma.j.issn.2095-0160.2015.12.009 Published 2015-12-10 Cite as Chin J Exp Ophthalmol, 2015,33(12): 1095-1101. Abstract [Download PDF] [Read Full Text] Background Choroidal neovascularization (CNV) is one of the primary causes leading to visual damage in […]
Modification and evaluation of ameliorative oxygen-induced retinopathy mouse model
Authors: Liu Aihua, Sun Jing, Zhang Hong DOI: 10.3760/cma.j.issn.2095-0160.2015.12.012 Published 2015-12-10 Cite as Chin J Exp Ophthalmol, 2015,33(12): 1108-1112. Abstract [Download PDF] [Read Full Text] Background Retinal neovascularization is associated with various disorders.Studying the pathogenesis of retinal neovascularization is of important significance.Oxygen-induced retinopathy(OIR) […]
Inhibitory effect of gamma-secretase inhibitor on retinal neovascularization and regulative mechanism of Notch1 signal pathway
Authors: Cheng Zhixing, Xie Jie, Meng Qianli DOI: 10.3760/cma.j.cn115989-20220820-00384 Published 2022-11-10 Cite asChin J Exp Ophthalmol, 2022, 40(11): 1031-1037. Abstract [View PDF] [Read Full Text] Objective To investigate the inhibitory effect and underlying mechanism of gamma-secretase inhibitor blocking Notch1 signaling on […]
Establishment of lens opacity model in Grx2 knockout mice based on CRISPR/cas9 system and the role of Grx2 in the pathogenesis of cataract
·Experimental Research· Establishment of a lens opacity model in Grx2 knockout mice based on the CRISPR/cas9 system and the role of Grx2 in cataract pathogenesis Guo Yong1, Guo Chenjun2, Zhang Jie2, Ning Xiaona2, Chen Xi3, Yan Hong1 1Department of Ophthalmology, Xi’an People’s Hospital, Xi’an Fourth Hospital, Shaanxi Eye Hospital, Xi’an 710004, China; 2Department of Ophthalmology, […]
Advances in rodent models of retinal neovascularization
Authors: Xu Qianhui, Chen Jun, Shao Yi DOI: 10.3760/cma.j.cn115989-20200211-00064 Published 2022-10-10 Cite asChin J Exp Ophthalmol, 2022, 40(10): 996-998. Abstract [View PDF] [Read Full Text] Retinal neovascularization (RNV) originating from retinal blood vessels is one of the main pathological features of many ocular […]