Tag: Oxidative damage

Establishment of lens opacity model in Grx2 knockout mice based on CRISPR/cas9 system and the role of Grx2 in the pathogenesis of cataract

2022, No. 10, Experimental Science

·Experimental Research· Establishment of a lens opacity model in Grx2 knockout mice based on the CRISPR/cas9 system and the role of Grx2 in cataract pathogenesis Guo Yong1, Guo Chenjun2, Zhang Jie2, Ning Xiaona2, Chen Xi3, Yan Hong1 1Department of Ophthalmology, Xi’an People’s Hospital, Xi’an Fourth Hospital, Shaanxi Eye Hospital, Xi’an 710004, China; 2Department of Ophthalmology, […]

Inhibitory effect of melatonin on pyroptosis of lens epithelium cells and its mechanism

2022, No. 05, Experimental Science

Authors: Yang Xin,  Liu Xuhui,  Meng Jia,  Fang Mengyuan,  Zhang Fengyan DOI: 10.3760/cma.j.cn115989-20210516-00307 Published 2022-05-10 Cite asChin J Exp Ophthalmol, 2022, 40(5): 414-421. Abstract                              [View PDF] [Read Full Text] Objective To investigate the inhibitory effect of melatonin on pyroptosis of lens epithelium cells (HLECs) induced […]