Tag: Rat

Modulation of MEK/ERK and PI3K/Akt pathways to the expression of DDR2 and MMP-13 in choroidal neovascularization

Authors: Yang Xiumei,  Wang Yusheng,  Zhang Jian,  Li Yan,  Yao Libo DOI: 10.3760/cma.j.issn.2095-0160.2015.08.002 Published 2015-08-10 Cite as Chin J Exp Ophthalmol, 2015,33(8): 678-685. Abstract                              [Download PDF] [Read Full Text] Background It is estimated that discoidin domain receptor 2 (DDR2) and matrix metalloproteinase-13 […]

Establishment of chronic ocular hypertension rat model by transgoniscope laser photocoagulation to trabecular meshwork and its comparison with translimbal laser photocoagulation

Authors: Ma Di,  Huang Chukai,  Cen Lingping,  Zhang Mingzhi DOI: 10.3760/cma.j.issn.2095-0160.2016.07.002 Published 2016-07-10 Cite as Chin J Exp Ophthalmol, 2016,34(7): 580-584. Abstract                              [Download PDF] [Read Full Text] Background The establishment of chronic ocular hypertension is a basis for the research of glaucoma.Previous laser photocoagulation method to […]

In vitro effects of bone marrow-derived mesenchymal stem cells on the biological behavior of lipopolysaccharide-activated retinal microglia

Authors: Huang Libin,  Xu Guoxing,  Xie Maosong,  Lin Wen,  Cui Yi,  Li Jianbing DOI: 10.3760/cma.j.issn.2095-0160.2016.09.002 Published 2016-09-10 Cite as Chin J Exp Ophthalmol, 2016,34(9): 773-779. Abstract                              [Download PDF] [Read Full Text] Background Retinal microglia(RMG) plays an important role in the pathogenesis of retinal degenerative diseases, while chemokine CX3CL1 participates in the […]

Protective effects of intravitreal injection of nerve growth factor on retinal ganglion cells in early diabetic rats

Authors: Lyu Hang,  Wang Qichang,  Tang Luosheng DOI: 10.3760/cma.j.issn.2095-0160.2019.06.005 Published 2019-06-10 Cite as Chin J Exp Ophthalmol, 2019,37(6): 425-431. Abstract                              [View PDF] [Read Full Text] Objective To investigate the protective effect of intravitreal injection of nerve growth factor (NGF) on apoptosis of retinal ganglion cells (RGCs) in early […]

Distribution of lanosterol synthase and lanosterol in cornea, lens and retina tissue of rats

Authors: Kang Lihua,  Shen Xinyue,  Yang Mei,  Zhang Guowei,  Zhang Junfang,  Qin Bai,  Yang Ling,  Hu Nan,  Guan Huaijin DOI: 10.3760/cma.j.issn.2095-0160.2017.03.003 Published 2017-03-10 Cite as Chin J Exp Ophthalmol, 2017,35(3): 201-206. Abstract                               [Download PDF] [Read Full Text] Background Researches showed that triterpenoids, with a similar structure to lanosterol, has therapeutical effect on many systemic […]