Tag: Sigma-1 receptor

Research advances in neuroprotective role of sigma-1 receptor in retina

Authors: Ma Xiaochen,  Liu Hongling DOI: 10.3760/cma.j.cn115989-20200110-00017 Published 2023-05-10 Cite as Chin J Exp Ophthalmol, 2023, 41(5): 512-515. Abstract                              [Download PDF] [Read Full Text] Retinal degenerative diseases are a major contributor to visual impairment worldwide, and research related to retinal degenerative diseases […]

Inhibiting effect of retinal Sigma-1 receptor antagonist on the form deprivation myopia in guinea pigs and its mechanism

Authors: Chen Yuanyuan,  Xie Fujuan,  Li Haibo,  Guan Yuxin,  Mao Junfeng DOI: 10.3760/cma.j.cn115989-20200615-00433 Published 2021-06-10 Cite asChin J Exp Ophthalmol, 2021, 39(6): 477-482. Abstract                              [View PDF] [Read Full Text] Objective To investigate the role and mechanism of retinal Sigma-1 receptor antagonist N, N-diethyl-2-[4-methoxy-3-(2-phenylethoxy)phenyl]ethanaminehydrochloride (NE-100) in […]