Authors: Sun Yanyan, Yang Xu, An Huijuan, Li Qingfu, Bao Yuzhou DOI: 10.3760/cma.j.issn.2095-0160.2015.09.008 Published 2015-09-10 Cite as Chin J Exp Ophthalmol, 2015,33(9): 805-810. Abstract [Download PDF] [Read Full Text] Background Oxidative stress is a pathophysiological process of retina, so it is very […]
Tag: Cell line
Establishment of mouse model of orbital diffuse large B cell lymphoma
Authors: Li Shiyun, Sun Fengyuan DOI: 10.3760/cma.j.issn.2095-0160.2015.11.005 Published 2015-11-10 Cite as Chin J Exp Ophthalmol, 2015,33(11): 981-984. Abstract [Download PDF] [Read Full Text] Background Recently, the morbidity of orbital lymphoma increased gradually, and we have made deeper research in pathology, therapy and pathogenesis […]
Inhibition of PTB-associated splicing factor on IGF-1/VEGF signaling pathway in retinal vascular endothelial cells
Authors: Tian Fang, Dong Lijie, Ji jie, Zhou Yu, Li Wenbo, Bai Lingling, Wang Fei, Qi Chen, Su Chang, Zhang Xiaomin, Li Xiaorong DOI: 10.3760/cma.j.issn.2095-0160.2016.01.003 Published 2016-01-10 Cite as Chin J Exp Ophthalmol, 2016,34(1): 11-16. Abstract [Download PDF] [Read Full Text] Background Retinal neovascularization (RNV) is common findings of many fundus diseases.Research showed that insulin-like growth factor-1 […]
Rapid differentiation of human ESCs into RPE cells by defined xeno-free culture system
Authors: Liu Qiuhui, Wang Jing, Tian Rong, Wang Xiao, Cao Di, Lu Jing, Luo Yan DOI: 10.3760/cma.j.issn.2095-0160.2016.06.002 Published 2016-06-10 Cite as Chin J Exp Ophthalmol, 2016,34(6): 484-488. Abstract [Download PDF] [Read Full Text] Background Subretinal transplantation of retinal pigment epithelium (RPE) cells for the treatment of age-related […]
Inhibition effects of sulforaphane-induced autophagy flux to cell proliferation on ex vivo human capsular bags
Authors: Liu Hanruo, Yuan Bowei, An Ying, Wan Xiuhua DOI: 10.3760/cma.j.issn.2095-0160.2017.03.009 Published 2017-03-10 Cite as Chin J Exp Ophthalmol, 2017,35(3): 226-232. Abstract [Download PDF] [Read Full Text] Background Sulforaphane (SFN) is an effective chemopreventive agent and can regulate the biological molecular mechanisms to inhibit the overgrowth of cells.Autophagy is […]
Mediated effects of endoplasmic reticulum stress on light-induced apoptosis and inflammation of human retinal pigment epithelial cell
Authors: Jiang Wenjing, Zhang Lina, Yu Xiao, Niu Yingjun DOI: 10.3760/cma.j.issn.2095-0160.2017.09.010 Published 2017-09-10 Cite as Chin J Exp Ophthalmol, 2017,35(9): 816-823. Abstract [Download PDF] [Read Full Text] Background The light damage model of retinal pigment epithelium (RPE) cells is a research direction of retinal degeneration diseases, and RPE cell […]
Neuroprotective effects of brimonidine on retinal ganglion cells induced by oxidative stress mitochondrial dysfunction
Authors: Wang Lu, Lin Binwu, Wang Yan, Pang Long DOI: 10.3760/cma.j.issn.2095-0160.2018.01.003 Published 2018-01-10 Cite as Chin J Exp Ophthalmol, 2018,36(1): 12-15. Abstract [Download PDF] [Read Full Text] Objective To explore whether brimonidine has a protective effect on retinal ganglion cells (RGCs) through improving mitochondrial function under the oxidative stress. […]