Tag: Diabetic retinopathy

Protective effect of asiatic acid on blood-retinal barrier in diabetic rats

Authors: Fang Mengyuan,  Li Qiuming,  Yang Xin,  Wan Weiwei,  Long Yang,  Liu Hongzhuo,  Wan Wencui DOI: 10.3760/cma.j.cn115989-20201024-00713 Published 2021-07-10 Cite asChin J Exp Ophthalmol, 2021, 39(7): 593-601. Abstract                              [View PDF] [Read Full Text] Objective To investigate the protective effect of asiatic acid (AA) on blood-retinal […]

Inhibitory effect of miR-146a on high glucose-induced apoptosis of retinal microvascular endothelial cells and its mechanism

Authors:  Gao Fei,  Wu Zhipeng,  Ruan Yihua DOI: 10.3760/cma.j.cn115989-20190703-00286 Published 2021-05-10 Cite asChin J Exp Ophthalmol, 2021, 39(5): 398-403. Abstract                               [View PDF] [Read Full Text] Objective To investigate the effect of microRNA-146a (miR-146a) on apoptosis of human retinal microvascular endothelial cells (HRMECs) induced by high […]

RNA-seq and its application in diabetic retinopathy

Authors: Nie Zetong,  Hu Bojie DOI: 10.3760/cma.j.cn115989-20190806-00337 Published 2021-05-10 Cite asChin J Exp Ophthalmol, 2021, 39(5): 450-453. Abstract                              [View PDF] [Read Full Text] RNA-seq is a transcriptome analysis method using deep sequencing technology, which uses high-throughput next-generation sequencing technology to investigate, characterize and quantify transcriptome.It […]

Research progress in biomarkers of diabetic macular edema on optical coherence tomography

Authors: Jiang Jingwen,  Chen Changzheng DOI: 10.3760/cma.j.cn115989-20190617-00264 Published 2021-01-10 Cite as Chin J Exp Ophthalmol, 2021,39(01): 89-92. Abstract                               [View PDF] [Read Full Text] Diabetic retinopathy (DR) is a common ocular complication in patients with diabetes, and diabetic macular edema (DME) is the main cause of […]

Network pharmacology analysis of metformin against diabetic retinopathy

Authors: Chen Yuan,  Xing Qian,  Huang Zhengru DOI: 10.3760/cma.j.cn115989-20191215-00543 Published 2020-12-10 Cite as Chin J Exp Ophthalmol, 2020,38(12): 1011-1015. Abstract                               [View PDF] [Read Full Text] Objective To explore the pharmacological molecular mechanisms of metformin against diabetic retinopathy (DR) based on network pharmacology approach. Methods After […]

Inhibitory effects of miR-146a on retinal inflammation induced by high glucose in human retinal endothelial cells

Authors: Gu Shun,  Zhan Pengfei,  Wang Wenjuan,  Wang Xiaolu,  Wei Tingting,  Zhu Lingpeng,  Wang Yangningzhi,  Yin Li,  Xie Tianhua,  Yao Yong DOI: 10.3760/cma.j.cn115989-20190213-00051 Published 2020-09-10 Cite as Chin J Exp Ophthalmol, 2020,38(09): 733-739. Abstract                               [View PDF] [Read Full Text] Objective To observe the effects of […]

Interpretation of Diabetic Retinopathy Preferred Practice Pattern®

Authors: Li Xiaorong,  Yang Qianhui DOI: 10.3760/cma.j.cn115989-20200518-00350 Published 2020-09-10 Cite as Chin J Exp Ophthalmol, 2020,38(09): 795-798. Abstract                               [View PDF] [Read Full Text] The numbers of population with diabetes have risen sharply worldwide.China has become a country with high incidence of diabetes.Diabetic retinopathy (DR), as […]

Research progress of exosomes in diabetic retinopathy

Authors: Zhang Hui,  Zhang Xiaomin,  Li Xiaorong DOI: 10.3760/cma.j.cn115989-20200424-00285 Published 2020-09-10 Cite as Chin J Exp Ophthalmol, 2020,38(09): 799-803. Abstract                               [View PDF] [Read Full Text] Exosomes are small extracellular vesicles secreted by cells and carry many biological molecules, such as mRNA, microRNA, proteins, and transcription […]

Changes of serum complement factors in patients with diabetic retinopathy

Authors: Sun Hongyan,  Ma Ruirui,  Chen Jiayu,  Yu Xuhui,  Yang Mingming DOI: 10.3760/cma.j.cn115989-2019051-00212 Published 2020-09-10 Cite as Chin J Exp Ophthalmol, 2020,38(09): 754-759. Abstract                               [View PDF] [Read Full Text] Objective To detect the changes of serum complement factors C3 and C4 in diabetic retinopathy (DR) […]

Changes of brain function in resting-state in patients with nonproliferative diabetic retinopathy assessed by fractional low-frequency amplitude technique

Authors: Qi Chenxing,  Huang Xin,  Tong Yan,  Shen Yin DOI: 10.3760/cma.j.cn115989-20190920-00406 Published 2020-09-10 Cite as Chin J Exp Ophthalmol, 2020,38(09): 760-765. Abstract                               [View PDF] [Read Full Text] Objective To study the changes of brain function in patients with diabetic retinopathy (DR) by using resting-state functional […]