Authors: Fan Xue, Rong Weining Corresponding author: Rong Weining, Email: moc.621624gniniewgnor Published:2026-07-10 DOI: 10.3760/cma.j.cn115989-20230731-00054 ABSTRACT Cilia widely exist in most cell types of the human body, and the dysfunction of cilia can affect various organs. The outer segment of the photoreceptor is a kind of highly differentiated primary sensory cilium, and its structure and function […]
Tag: Gene
Application of single-cell RNA sequencing in the study of ophthalmologic diseases
Authors: Jiang Bo, Lu Peirong DOI: 10.3760/cma.j.cn115989-20210419-00265 Published: 2024 -09 -10 Citation: Jiang B, Lu PR. Application of single-cell RNA sequencing in the study of ophthalmologic diseases[J]. Chin J Exp Ophthalmol,2024,42(9):852-857. DOI: 10.3760/cma.j.cn115989-20210419-00265. ABSTRACT [Download PDF] [Read Full Text] Single-cell RNA sequencing (scRNA-seq) is a powerful and rapidly developing emerging technology that allows complete analysis of […]
Next generation sequencing based molecular genetic analysis of a Chinese Han family with autosomal retinitis pigmentosa
Authors: Zhou Xiaomin, Huang Hui, Wang Ying, Wu Jing, Fan Ning, Jiang Shanming, Liu Xuyang DOI: 10.3760/cma.j.issn.2095-0160.2015.08.006 Published 2015-08-10 Cite as Chin J Exp Ophthalmol, 2015,33(8): 699-703. Abstract [Download PDF] [Read Full Text] Background Retinitis pigmeutosa (RP) is a progressive inheritance disease. […]
Advances in molecular genetics of exfoliation syndrome
Authors: Yin Yan, Fan Ning, Liu Xuyang DOI: 10.3760/cma.j.issn.2095-0160.2015.08.019 Published 2015-08-10 Cite as Chin J Exp Ophthalmol, 2015,33(8): 760-763. Abstract [Download PDF] [Read Full Text] Exfoliation syndrome (XFS), one of the most common causes of glaucoma, represents an age related, complex, multifactorial and […]
Monitoring function of microglia in retina and nerve system diseases
Authors: Xu Jia, Jin Zibing DOI: 10.3760/cma.j.cn115989-20200918-00656 Published 2022-08-10 Cite asChin J Exp Ophthalmol, 2022, 40(8): 758-764. Abstract [View PDF] [Read Full Text] Microglia are the resident macrophages in the central nervous system (CNS), like Kupffer cells in the liver and dust […]
Diabetic retinopathy and serum vitamin D level
Authors: Wang Yixin, Yao Yong DOI: 10.3760/cma.j.cn115989-20190115-00012 Published 2022-07-10 Cite asChin J Exp Ophthalmol, 2022, 40(7): 690-694. Abstract [View PDF] [Read Full Text] Diabetic retinopathy (DR) is one of the most severe chronic complications of diabetes, which […]
RNA-seq and its application in diabetic retinopathy
Authors: Nie Zetong, Hu Bojie DOI: 10.3760/cma.j.cn115989-20190806-00337 Published 2021-05-10 Cite asChin J Exp Ophthalmol, 2021, 39(5): 450-453. Abstract [View PDF] [Read Full Text] RNA-seq is a transcriptome analysis method using deep sequencing technology, which uses high-throughput next-generation sequencing technology to investigate, characterize and quantify transcriptome.It […]
Network pharmacology analysis of metformin against diabetic retinopathy
Authors: Chen Yuan, Xing Qian, Huang Zhengru DOI: 10.3760/cma.j.cn115989-20191215-00543 Published 2020-12-10 Cite as Chin J Exp Ophthalmol, 2020,38(12): 1011-1015. Abstract [View PDF] [Read Full Text] Objective To explore the pharmacological molecular mechanisms of metformin against diabetic retinopathy (DR) based on network pharmacology approach. Methods After […]
Association of TLR4 polymorphisms with primary open angle glaucoma in Chinese population
Authors: Shu Yi, Xu Jiaxin, Yang Chen, Chen Yilian, Luo Qian, Gong Bo, Yang Zhenglin, Huang Guo DOI: 10.3760/cma.j.cn115989-20191120-00505 Published 2020-08-10 Cite as Chin J Exp Ophthalmol, 2020,38(08): 659-664. Abstract [View PDF] [Read Full Text] Objective To detect whether Toll-like receptor 4 (TLR4) polymorphisms contributed to […]
Review and analysis on knockout mouse models with cataract
Authors: Wu Zehua, Liu Xiangyuan, Li Yuying, Zhong Zilin, Chen Jianjun DOI: 10.3760/cma.j.cn115989-20190227-00087 Published 2020-08-10 Cite as Chin J Exp Ophthalmol, 2020,38(08): 710-714. Abstract [View PDF] [Read Full Text] Cataract is the leading cause of blindness worldwide, which is a generally clinical and genetic heterogeneity eye […]