Tag: Gene transfer techniques

Construction of Smac siRNA lentiviral vector and its silencing effect on Smac gene in human LECs

Authors: Li Yun,  Zheng Guangying,  Jiang Yu DOI: 10.3760/cma.j.issn.2095-0160.2016.03.002 Published 2016-03-10 Cite as Chin J Exp Ophthalmol, 2016,34(3): 199-204. Abstract                              [Download PDF] [Read Full Text] Background Research comfirmed that second mitochondrial activator of caspase (Smac) is a promoting tumor cell apoptosis protein.Our previous study showed that the expression […]

The efficiency and safety assessment of Entranster™ nanoparticle carrier for CD25 siRNA transfection in rat cornea

Authors:Qin Qin,  Shi Yunjie,  Zhao Min DOI: 10.3760/cma.j.issn.2095-0160.2016.10.005 Published 2016-10-10 Cite as Chin J Exp Ophthalmol, 2016,34(10): 888-895. Abstract                              [Download PDF] [Read Full Text] Background Gene transfection is an effective therapeutic avenue to target many kinds of eye diseases.Non-viral vectors with high transfection efficiency, long-term expression, […]