Tag: RNA

Transcriptomics-based analysis of potential pathogenic mechanisms in presenile cataract

Authors: Xu Su, Si Wei, Zhang Yuhang, Huang Yuelin, Li Fuzhen, Shao Jingzhi, Mao Yi, Du Shanshan, Qi Ying, Zhang Fengyan DOI: 10.3760/cma.j.cn115989-20250425-00136 Published: 2026 -03 -10 Citation Xu Su, Si Wei, Zhang Yuhang, et al. Transcriptomics-based analysis of potential pathogenic mechanisms in presenile cataract[J]. Chin J Exp Ophthalmol, 2026, 44(3):260-267. DOI: 10.3760/cma.j.cn115989-20250425-00136. ABSTRACT            […]

Inhibitory effect of radixin shRNA on retinal neovascularization induced by hyperoxia in mice

Authors: Wang Longmei,  Yang Xia,  Yan Lin,  Liu Ting,  Dong Xiaoguang,  Xu Haifeng DOI: 10.3760/cma.j.issn.2095-0160.2015.12.008 Published 2015-12-10 Cite as Chin J Exp Ophthalmol, 2015,33(12): 1089-1094. Abstract                              [Download PDF] [Read Full Text] Background Retinal neovascularization is pathological basis of a variety of fundus […]

Inhibition of CCN1 siRNA on retinal endothelial cells

Authors: Di Yu,  Zhang Yiou,  Wang Aiyuan,  Chen Xiaolong DOI: 10.3760/cma.j.issn.2095-0160.2016.01.005 Published 2016-01-10 Cite as Chin J Exp Ophthalmol, 2016,34(1): 24-29. Abstract                              [Download PDF] [Read Full Text] Background Cysteine-rich 61(Cyr61)/CCN1 has been reported to stimulate retinal neovascularization (RNV) in retinopathy of prematurity (ROP). However, whether CCN1 small interfering RNA […]

Construction of Smac siRNA lentiviral vector and its silencing effect on Smac gene in human LECs

Authors: Li Yun,  Zheng Guangying,  Jiang Yu DOI: 10.3760/cma.j.issn.2095-0160.2016.03.002 Published 2016-03-10 Cite as Chin J Exp Ophthalmol, 2016,34(3): 199-204. Abstract                              [Download PDF] [Read Full Text] Background Research comfirmed that second mitochondrial activator of caspase (Smac) is a promoting tumor cell apoptosis protein.Our previous study showed that the expression […]

The promoting effects of insulin-like growth factor 1 on the biological behaviour of human retinal vascular endothelial cells

Authors: Wang Mengjiao,  Liu Gaoqin,  Xu Jing,  Li Dan,  Lu Peirong DOI: 10.3760/cma.j.issn.2095-0160.2017.05.007 Published 2017-05-10 Cite as Chin J Exp Ophthalmol, 2017,35(5): 417-422. Abstract                               [Download PDF] [Read Full Text] Background The suppression of retinal angiogenesis is one of primary treatment targets for retinal vascular diseases, so seeking the intervention targets […]