Tag: Inflammasomes

Role of NLRP3 inflammasome signaling pathway in the occurrence and development of diabetic keratopathy

Authors: Wan Luqin,  Zhou Qingjun,  Xie Lixin DOI: 10.3760/cma.j.cn115989-20190618-00266 Published 2022-07-10 Cite asChin J Exp Ophthalmol, 2022, 40(7): 680-684. Abstract                                       [View PDF] [Read Full Text] Diabetic keratopathy is a chronic complication of diabetes caused by abnormal metabolites accumulation, oxidative stress, abnormal inflammation […]

Effect of ROS/NLRP3/Caspase-1 signaling pathway on the apoptosis of retinal pigment epithelial cells induced by high glucose

Authors: Li Hongsong,  Li Rong,  Wang Lijun,  Liao Dingying,  Wang Jianming DOI: 10.3760/cma.j.cn115989-20210420-00267-1 Published 2022-01-10 Cite asChin J Exp Ophthalmol, 2022, 40(1): 6-12. Abstract                              [View PDF]  [Read Full Text] Objective To investigate the effect of the nucleotide-binding domain, leucine-rich-containing family, pyrin […]

NLRP3 inflammasome and its role in age-related macular degeneration

Authors: Chen Lu,  Xie Ping,  Hu Zizhong DOI: 10.3760/cma.j.cn115989-20210922-00527 Published 2022-01-10 Cite as Chin J Exp Ophthalmol, 2022, 40(1): 73-77. Abstract                               [View PDF] [Read Full Text] Age-related macular degeneration (AMD), the leading cause of central vision loss among people aged 50 years […]