Authors: Dou Zexia, Ru Yusha, Liu Huijuan, Zeng Xiaoyu, Meng Zhu, Gu Zhongxiu, Zhang Yan, Zhao Shaozhen DOI: 10.3760/cma.j.issn.2095-0160.2017.06.004 Published 2017-06-10 Cite as Chin J Exp Ophthalmol, 2017,35(06): 498-505. Abstract [Download PDF] [Read Full Text] Background Reasearches showed that α-melanocyte-stimulating hormone (α-MSH) inhibits inflammation and ameliorates the ocular surface abnormalities in a scopolamine-induced […]
Tag: Rats
Protection of polysaccharides of dendrobium candidum on blood-retinal barrier in diabatic rats and its mechanism
Authors: Li Jingwen, Li Guowen, Lu Jun, Li Chunxia DOI: 10.3760/cma.j.issn.2095-0160.2017.07.008 Published 2017-07-10 Cite as Chin J Exp Ophthalmol, 2017,35(07): 611-616. Abstract [Download PDF] [Read Full Text] Background The pathogenesis of diabetic retinopathy (DR) involves a variety of biological pathways.Recently, inflammation factor has been thought to paly an important […]
Regulation of high glucose to the expression of Toll-like receptor 4 in retinal ganglion cells and its significance
Authors: Hu Lili, Ai Ming, Yang Hongxia, Jiang Shuanghong DOI: 10.3760/cma.j.issn.2095-0160.2017.07.005 Published 2017-07-10 Cite as Chin J Exp Ophthalmol, 2017,35(07): 597-602. Abstract [Download PDF] [Read Full Text] Background Studies show that retinal neurodegeneration may precede retinal microvascular changes in diabetes mellitus.The apoptosis of retinal ganglion cells (RGCs) is an […]
Photobiomodulation of light emitting diode irradiation on apoptosis of retinal neuronal cells induced by high-glucose
Authors: Zhang Limin, Zhang Fengjiu, Lin Anling, Peng Xiangdong, Yang Jianling, Yu Lingyan, Wang Haiming, Gao Shikai DOI: 10.3760/cma.j.issn.2095-0160.2017.07.004 Published 2017-07-10 Cite as Chin J Exp Ophthalmol, 2017,35(07): 591-596. Abstract [Download PDF] [Read Full Text] Background To study the pathogenesis and management of diabetic retinopathy (DR) has an important clinical significance.With the development […]
Aggravation effects of JAK-STAT signaling pathway in retinal ischemia reperfusion injury
Authors: Yang Le, Shi Rui, Shen Jiaquan, Xue Yushun DOI: 10.3760/cma.j.issn.2095-0160.2017.08.004 Published 2017-08-10 Cite as Chin J Exp Ophthalmol, 2017,35(8): 690-694. Abstract [Download PDF] [Read Full Text] Background Retinal ischemia reperfusion injury (RIRI) is a common pathological process of many retinal vascular diseases with comprehensive pathogenesis mechanism.Researches showed that […]
Inflammation-causing effects and mechanism of natural killer cells in experimental autoimmune uveitis rats
Authors: Li Mohan, Bao Ning, Liu Dongwei, Tao Liming, Jiang Zhengxuan DOI: 10.3760/cma.j.issn.2095-0160.2017.09.007 Published 2017-09-10 Cite as Chin J Exp Ophthalmol, 2017,35(9): 799-804. Abstract [Download PDF] [Read Full Text] Background Experimental autoimmune uveitis (EAU) is a common animal model of uveitis.Natural killer (NK) cells have been confirmed to be a […]
Regulation of sericin on retinal endoplasmic reticulum stress specific caspase-12 dependent pathway and inhibition on apoptosis in diabetic rat
Authors: Dong Zhijun, Yang Nan, Chen Zhihong, Yang Fan, Yu Hongfei, Dong Weili, Zhang Tiemin DOI: 10.3760/cma.j.issn.2095-0160.2017.12.003 Published 2017-12-10 Cite as Chin J Exp Ophthalmol, 2017,35(12): 1067-1072. Abstract [Download PDF] [Read Full Text] Background Endoplasmic reticulum stress (ERS) specific caspase-12 dependent pathway plays a key role in cell apoptosis, and apoptosis is […]
Neuroprotective effects of tianmagouteng decoction on retinal ganglion cells in optic nerve crush model
Authors: Li Yujie, Ma Ke, Zhang Haijuan, Wang Haiyan DOI: 10.3760/cma.j.issn.2095-0160.2018.02.004 Published 2018-02-10 Cite as Chin J Exp Ophthalmol, 2018,36(2): 91-95. Abstract [Download PDF] [Read Full Text] Objective To investigate the neuroprotective effect and antioxidation mechanism of tianmagouteng decoction on retinal ganglion cells (RGCs) in optic nerve crush model. […]
Protective effects of carnosic acid on retinal ganglion cells in acute ocular hypertension rats model
Authors: He Liye, Liang Liang, Zhu Mengnan, Xiao Changyi, Tu Xiaokun DOI: 10.3760/cma.j.issn.2095-0160.2018.04.005 Published 2018-04-10 Cite as Chin J Exp Ophthalmol, 2018,36(4): 254-258. Abstract [Download PDF] [Read Full Text] Objective To observe the protective effects of carnosic acid on retinal ganglion cells (RGCs) in acute ocular hypertension rats model. Methods […]