Authors: Wu Wei, Qu Ya, Wang Lei, Zeng Yuxiao, Xu Haiwei, Yin Zhengqin DOI: 10.3760/cma.j.issn.2095-0160.2016.09.004 Published 2016-09-10 Cite as Chin J Exp Ophthalmol, 2016,34(9): 786-790. Abstract [Download PDF] [Read Full Text] Background Normal ultrastructure is the anatomical basis of retinal pigment epithelial(RPE)cells to perform normal physiological function.At present the precipitation method […]
Tag: Rats
The efficiency and safety assessment of Entranster™ nanoparticle carrier for CD25 siRNA transfection in rat cornea
Authors：Qin Qin, Shi Yunjie, Zhao Min DOI: 10.3760/cma.j.issn.2095-0160.2016.10.005 Published 2016-10-10 Cite as Chin J Exp Ophthalmol, 2016,34(10): 888-895. Abstract [Download PDF] [Read Full Text] Background Gene transfection is an effective therapeutic avenue to target many kinds of eye diseases.Non-viral vectors with high transfection efficiency, long-term expression, […]
The effects of fluoxetine and its machanism on the restores of visual cortex plasticity in the adult rats by visual electrophysiological research
Authours：Xie Laiqing, Xu Guoxu, Ni Yong, Wei Xiaohong, Lou Hui DOI: 10.3760/cma.j.issn.2095-0160.2016.11.002 Published 2016-11-10 Cite as Chin J Exp Ophthalmol, 2016,34(11): 965-970. Abstract [Download PDF] [Read Full Text] Background Fluoxetine (Flx), a selective serotonin reuptake inhibitor, promotes neurogenesis and synaptogenesis in the adult hippocampus.So it is inferred that Flx plays a role […]
Inhibitory effects of α-crystallin on optic nerve astrocytes proliferation, activation and secretion stimulated by lipopolysaccharide
Authors：Liu Xiao, Shao Weiyang, Gu Xianliang, Wang Yi DOI: 10.3760/cma.j.issn.2095-0160.2016.12.007 Published 2016-12-10 Cite as Chin J Exp Ophthalmol, 2016,34(12): 1082-1086. Abstract [Download PDF] [Read Full Text] Background Glial scaring induced by the activation and proliferation of astrocytes after optical nerve damage is one of causes of neural axons difficult to regeneration.Researches […]
Application of modified retinal flatmount combined with immunofluorescence staining in oxygen-induced retinopathy model
Authors：Li Rong, Yao Guomin, Wang Xiaodi DOI: 10.3760/cma.j.issn.2095-0160.2016.12.005 Published 2016-12-10 Cite as Chin J Exp Ophthalmol, 2016,34(12): 1077-1080. Abstract [Download PDF] [Read Full Text] Background Retinal flatmount of oxygen-induced retinopathy (OIR) animal models is a useful tool in the study of ischemic retinopathy.The retinas of OIR of rat or mouse […]
Inhibitory effects of jiajianzhujing decoction containing serum on proliferation of rat choroidal vascular endothelial cells
Authors：Liu Yanjiang, Kang Zefeng, Xing Kai, Liu Jian DOI: 10.3760/cma.j.issn.2095-0160.2016.12.003 Published 2016-12-10 Cite as Chin J Exp Ophthalmol, 2016,34(12): 1065-1071. Abstract [Download PDF] [Read Full Text] Background Choroidal neovascularization (CNV) of macular zone is one of blinding eye diseases.Conventional treatment methods include photodynamic therapy and intravitreal injection of anti-vascular endothelial growth […]
Protection of sericin to retinal microvessels and its mechanism in diabetic rats
Authors: Yu Hongfei, Dong Zhijun, Zhang Tiemin, Yang Fan DOI: 10.3760/cma.j.issn.2095-0160.2017.01.007 Published 2017-01-10 Cite as Chin J Exp Ophthalmol, 2017,35(1): 32-37. Abstract [Download PDF] [Read Full Text] Background Diabetic retinopathy (DR) is a chronic inflammatory disease, with pathological changes of retinal microvessels.Studies demonstrated that sericin has anti-inflammation and anti-oxidation […]
Promoting ocular surface restoration effects and anti-inflammatory mechanism of thymosin beta 4 in rat dry eye
Authors: Zhang Huiqin, Li Ying, Feng Lina, Xu Yonggen DOI: 10.3760/cma.j.issn.2095-0160.2017.02.005 Published 2017-02-10 Cite as Chin J Exp Ophthalmol, 2017,35(2): 114-121. Abstract [Download PDF] [Read Full Text] Background Studies showed that inflammation is associated with the pathogenesis and development of dry eyes, and tumor necrosis […]
Establishment of human scleral fibroblasts-seeded collagen matrix and its mechanical properties
Authors: Hu Shoulong, Li Li, Cui Dongmei, Zeng Junwen DOI: 10.3760/cma.j.issn.2095-0160.2017.02.004 Published 2017-02-10 Cite as Chin J Exp Ophthalmol, 2017,35(2): 108-113. Abstract [Download PDF] [Read Full Text] Background Excessive elongation of axis and expansion of sclera is one of the hot topics in the study of the pathogenesis of […]
Proventive effects of astaxanthin on metabolic cataract and its mechanism in type 1 diabetic rats
Authors: Yang Ming, Wang Zhiju, Deng Tingting, Pan Lin DOI: 10.3760/cma.j.issn.2095-0160.2017.03.007 Published 2017-03-10 Cite as Chin J Exp Ophthalmol, 2017,35(3): 217-224. Abstract [Download PDF] [Read Full Text] Background The pathogenesis mechanism of diabetic cataract has not been fully elucidated.Researches showed that multiple biological pathways participate in the pathogenesis of […]