Authors: Guo Jing, Chen Song, Wang Yun, Liang Xu DOI: 10.3760/cma.j.issn.2095-0160.2017.10.013 Published 2017-10-10 Cite as Chin J Exp Ophthalmol, 2017,35(10): 914-919. Abstract [Download PDF] [Read Full Text] Background Vitreoretinal surgery (VRS) is the main treatment of severe proliferative diabetic retinopathy (PDR), intravitreal injection of anti-VEGF drugs before VRS on […]
Tag: Vascular endothelial growth factor
Expression of CD147 in laser-induced rat choroidal neovascularization model
Authors: Wang Wenqiu, Lu Fengqing, Wang Hong, Sun Xiaodong DOI: 10.3760/cma.j.issn.2095-0160.2017.10.007 Published 2017-10-10 Cite as Chin J Exp Ophthalmol, 2017,35(10): 890-893. Abstract [Download PDF] [Read Full Text] Background The pathology of choroidal neovascularization (CNV) is not clear.CD147 plays a critical role in angiogenesis through activating […]
Effect of Cathepsin B and vascular endothelial growth factor on the retinal neovascularization induced by hyperoxia
Authors: Wang Wenjuan, Zhou Guohong DOI: 10.3760/cma.j.issn.2095-0160.2017.10.003 Published 2017-10-10 Cite as Chin J Exp Ophthalmol, 2017,35(10): 873-877. Abstract [Download PDF] [Read Full Text] Background Vascular endothelial growth factor (VEGF) plays a key role in the vascular development and neovascularization.Studies have proved that Cathepsin B is related to […]
The inhibitory effects of baicalein on overexpression of proline hydroxylase 2 in hypoxia-induced retinal glial cells
Authors: Yang Ning, Lu Qiang, Yuan Mengke, Zhang Han, Cui Wei DOI: 10.3760/cma.j.issn.2095-0160.2017.11.007 Published 2017-11-10 Cite as Chin J Exp Ophthalmol, 2017,35(11): 990-996. Abstract [Download PDF] [Read Full Text] Background Proline hydroxylase 2 (PHD2) is a degrading enzyme of hypoxia-inducible factor-1α (HIF-1α) and can regulate the expression of vascular endothelial […]
The effects of recombinant human platelet derived growth factor-BB on biological behaviours of human retinal vascular endothelial cells
Authors: Li Dan, Liu Gaoqin, Chen Lei, Wang Mengjiao, Lu Peirong DOI: 10.3760/cma.j.issn.2095-0160.2018.01.008 Published 2018-01-10 Cite as Chin J Exp Ophthalmol, 2018,36(1): 34-39. Abstract [Download PDF] [Read Full Text] Objective This study was to investigate the role of recombinant human platelet derived growth factor-BB(rhPDGF-BB) in the proliferation and migration of […]
Inhibitory effects of Genistein on hyperoxia-induced retinal neovascularization
Authors: He Ronghua, Zhou Guohong, Kong Li, Li Chenyu DOI: 10.3760/cma.j.issn.2095-0160.2018.01.007 Published 2018-01-10 Cite as Chin J Exp Ophthalmol, 2018,36(1): 29-33. Abstract [Download PDF] [Read Full Text] Objective To investigate the effect of Genistein, a tyrosinase inhibitor, on retinal neovascularization in mice. Methods Thirty-six 7-day-old C57BL/6J mice were randomly […]
Paying attention to the prognosis guiding effects of CNV dynamic changes based-OCT angiography in neovascular age-related macular degeneration after antiangiogenic therapy
Authors: Zhao Zhi, Sun Xiaodong DOI: 10.3760/cma.j.issn.2095-0160.2018.01.001 Published 2018-01-10 Cite as Chin J Exp Ophthalmol, 2018,36(1): 1-4. Abstract [Download PDF] [Read Full Text] Intravitreal injection of anti-vascular endothelial growth factor (VEGF) agents is a first line therapy for neovascular age-related macular degeneration (nAMD). However, how to predict […]
Analysis of long-term outcomes and causes influencing visual prognosis in eyes receiving anti-VEGF-A for wet age-related macular degeneration
Authors: Yang Shiqi, Sun Xiaodong DOI: 10.3760/cma.j.issn.2095-0160.2018.03.016 Published 2018-03-10 Cite as Chin J Exp Ophthalmol, 2018,36(3): 236-240. Abstract [Download PDF] [Read Full Text] As a progressive chronic disease, age-related macular degeneration (AMD) is the leading cause of blindness worldwide.However, current therapy for AMD shows a dramatic breakthrough.More […]
Recent advances of bevacizumab as an adjunct to trabeculectomy
Authors: Chen Juan, Yu Wenzhen DOI: 10.3760/cma.j.issn.2095-0160.2018.08.015 Published 2018-08-10 Cite as Chin J Exp Ophthalmol, 2018,36(8): 649-652. Abstract [Download PDF] [Read Full Text] Glaucoma is a group of diseases characterized by progressive optic nerve damage and characteristic visual field defect.Increased intraocular pressure is the main risk factor […]
Research progress of pathological relevant cytokines of neovascular eye diseases
Authors: Han Mengyu, Wang Zhijun, Jin Ming DOI: 10.3760/cma.j.issn.2095-0160.2018.08.013 Published 2018-08-10 Cite as Chin J Exp Ophthalmol, 2018,36(8): 636-642. Abstract [Download PDF] [Read Full Text] Neovascular eye diseases, with highly complicated and refractory, are one group of the most difficult problems for domestic and overseas clinical oculists in […]