Tag: Epigenetics

Research progress on the regulatory effect of lncRNA MALAT1 on neovascularization in ischemic retinopathy

Authors: Li Zhaojin, Di Yu DOI: 10.3760/cma.j.cn115989-20211130-00661 Published: 2025 -01 -10 Citation Li Zhaojin, Di Yu. Research progress on the regulatory effect of lncRNA MALAT1 on neovascularization in ischemic retinopathy[J]. Chin J Exp Ophthalmol, 2025, 43(01):92-96. DOI: 10.3760/cma.j.cn115989-20211130-00661. ABSTRACT                    [Download PDF] [Read Full Text] Ischemic retinopathies (IRs) […]

Epigenetic mechanism of myopia

Authors: Gong Wei, Liu Kun, He Xiangui DOI: 10.3760/cma.j.cn115989-20210330-00221 Published 2023-09-10 Cite as Chin J Exp Ophthalmol, 2023, 41(9): 939-943. Abstract                          【Download PDF】 【Read Full Text】 Myopia has become a serious public health problem, but its pathogenesis is still unclear, and effective interventions […]

Association between MeCP2 and proliferative vitreoretinopathy under the regulation of tumor necrosis factor

Authors: Xu Yuejuan,  Li Xiaohua DOI: 10.3760/cma.j.cn115989-20191111-00491 Published 2020-06-10 Cite as Chin J Exp Ophthalmol, 2020,38(06): 548-552. Abstract                               [View PDF] [Read Full Text] Proliferative vitreoretinopathy (PVR) is an ocular fundus disease involving multiple cytokines.Its important pathological process is epithelial-mesenchymal transition (EMT) of retinal pigment epithelium (RPE) […]

Changes in DNA methylation of retinal gene promoter regions and their significance in type 1 diabetic rats

Authors: Li Yahong,  Geng Chao,  Liu Shengnan,  Wang Qi,  Li Xiaorong,  Zhang Yan DOI: 10.3760/cma.j.cn115985-20190616-00262 Published 2020-04-10 Cite as Chin J Exp Ophthalmol, 2020,38(04): 291-299. Abstract                              [View PDF] [Read Full Text] Objective To study the methylation level of retinal gene promoter region […]

Relationship between microRNAs and myopia

Authors:Xiao Dan,  Lan Changjun,  Liao Xuan DOI: 10.3760/cma.j.issn.2095-0160.2019.07.014 Published 2019-07-10 Cite as Chin J Exp Ophthalmol, 2019,37(7): 569-572. Abstract                              [View PDF] [Read Full Text] MicroRNA (miRNA) is a kind of non-coding small RNAs, which can regulate target mRNA at post-transcriptional level and […]

Epigenetics—the new era of biomedical and ophthalmological research

Authors:He Shikun,  Ouyang Sha DOI: 10.3760/cma.j.issn.2095-0160.2016.10.001 Published 2016-10-10 Cite as Chin J Exp Ophthalmol, 2016,34(10): 865-873. Abstract                               [Download PDF] [Read Full Text] Epigenetics is a researching hot topic of worldwide now.Increasing evidence shows that the pathogenesis of human diseases is not […]