Category: 2022, No. 03

Attaching importance to the genetic diagnosis of early-onset high myopia

Author: Sheng Xunlun DOI: 10.3760/cma.j.cn115989-20210915-00517 Published 2022-03-10 Cite asChin J Exp Ophthalmol, 2022, 40(3): 193-198. Abstract According to the onset age, high myopia can be divided into late-onset high myopia (loHM) and early-onset high myopia (eoHM). Numerous genetic studies have shown that eoHM is different from loHM.EoHM, a special type of high myopia before school […]

Promoting effect of conditioned medium of human bone mesenchymal stem cells on proliferation, adhesion and neuronal differentiation of immortalized human Müller cell line

Authors: Ge Lingling,  Li Yijian,  Li Qiyou,  Gu Xianliang,  Huang Xiaona,  Tao Zui,  Xu Haiwei DOI: 10.3760/cma.j.cn115989-20210702-00386 Published 2022-03-10 Cite asChin J Exp Ophthalmol, 2022, 40(3): 199-209. Abstract Objective To explore the effects of conditioned medium of human bone marrow mesenchymal stem cells (BMSCs) on the proliferation, adhesion and differentiation of immortalized human Müller cell […]

Screening, identification and functional analysis of differential expression genes in rat visual cortex after monocular deprivation by RNA-Seq technique

Authors: Sun Yaling,  Yan Xingke,  Liu Anguo DOI: 10.3760/cma.j.cn115989-20201106-00750 Published 2022-03-10 Cite asChin J Exp Ophthalmol, 2022, 40(3): 210-215. Abstract Objective To screen differentially expressed genes (DEGs) in rat visual cortex after monocular deprivation by RNA sequencing technology, and to analyze the function of the DEGs. Methods Eighteen 14-day-old SD rats were randomly divided into […]

Protective effects of Slit2 on corneal epithelium and nerves in diabetic mice and its mechanism

Authors: Tian Le,  Li Dewei,  Xie Lixin,  Zhou Qingjun DOI: 10.3760/cma.j.cn115989-20200228-00119 Published 2022-03-10 Cite asChin J Exp Ophthalmol, 2022, 40(3): 216-226. Abstract Objective To explore the promoting effects of slit guidance ligand 2 (Slit2) on the repair of corneal epithelium and nerve damage in diabetic mice and possible molecular mechanism. Methods Sixty SPF C57BL/6 mice […]

Comparison of clinical outcome between femtosecond laser-assisted LASIK and SMILE for myopic astigmatism by vector analysis

Authors: Wang Shulin,  Pang Chenjiu,  Wang Hao,  Zhang Bo,  Gu Yuwei,  Li Jin DOI: 10.3760/cma.j.cn115989-20201206-00827 Published 2022-03-10 Cite asChin J Exp Ophthalmol, 2022, 40(3): 227-234. Abstract Objective To compare the accuracy and stability between corneal topography-guided femtosecond laser-assisted laser in situ keratomileusis (FS-LASIK) and small incision lenticule extraction (SMILE) for myopic astigmatism by vector analysis. […]

Multimodal imaging characteristics of combined hamartoma of retina and retinal pigment epithelium

Authors: Zhang Juan,  Cui Xiaoyan,  Li Juanjuan,  Li Hua,  Hu Zhulin,  Ma Yinyan,  Zhang Xiaofan DOI: 10.3760/cma.j.cn115989-20190928-00423 Published 2022-03-10 Cite asChin J Exp Ophthalmol, 2022, 40(3): 235-240. Abstract Objective To observe the multimodal imaging characteristics of combined hamartoma of the retina and retinal pigment epithelium (CHRRPE). Methods A cross-sectional study was conducted.Sixteen eyes of 16 […]

Agreement evaluation between adaptive optics visual simulator and conventional refraction methods

Authors: Zhou Guimei,  Tan Qingqing,  Liao Xuan,  Qian Jiulin,  Lan Changjun DOI: 10.3760/cma.j.cn115989-20200526-00375 Published 2022-03-10 Cite asChin J Exp Ophthalmol, 2022, 40(3): 241-246. Abstract Objective To evaluate the difference and agreement of cycloplegic refraction between adaptive optics visual simulator (VAO) and conventional refraction methods. Methods A diagnostic test study was conducted.Thirty-one eyes of 31 healthy […]

Promoting effects of Difrarel® on retinal function following panretinal photocoagulation in diabetic retinopathy

Authors: Zhang Moli,  Wei Wenbin,  Tian Bei DOI: 10.3760/cma.j.cn115989-20210325-00205 Published 2022-03-10 Cite asChin J Exp Ophthalmol, 2022, 40(3): 247-252. Abstract Objective To investigate the promoting effect of Difrarel® on retinal function following panretinal photocoagulation (PRP) in the eyes with diabetic retinopathy. Methods A non-randomized controlled study was performed.A total of 108 eyes of 108 patients […]

A randomized controlled clinical study of 0.01% and 0.02% atropine eye drops on myopia development in adolescents

Authors: Fu Aicun,  Rong Junbo,  Wang Weiqun,  Wei Li,  Zhang Junjie,  Zhao Bingxin,  Lyu Yong DOI: 10.3760/cma.j.cn115989-20190112-00007 Published 2022-03-10 Cite asChin J Exp Ophthalmol, 2022, 40(3): 253-259. Abstract Objective To compare the clinical efficacy and safety of 0.01% and 0.02% atropine eye drops on myopia development in adolescents. Methods A randomized controlled double-blind study was […]

Risk factors analysis of age-related macular degeneration in Tibetan of plateau area and establishment of nomogram prediction model

Authors: Zhang Xiaoying,  Guan Ruijuan,  Yan Xin,  Li Ling DOI: 10.3760/cma.j.cn115989-20200711-00487 Published 2022-03-10 Cite asChin J Exp Ophthalmol, 2022, 40(3): 260-265. Abstract Objective To determine the prevalence and risk factors for age-related macular degeneration (AMD) in Tibetan of plateau area, and to establish a nomogram prediction model. Methods A cross-sectional study was carried out.The 40-year-old […]