Category: Experimental Science

Metabolomics study of kidney tissue in a mouse model of oxygen-induced retinopathy

Authors: Dong Lijun,  Qi Hui,  Yang Yuhang,  Mao Xingxing,  Zhang Guoming,  Zhang Shaochong,  Lei Hetian DOI: 10.3760/cma.j.cn115989-20220526-00248 Published 2024-01-10 Cite as Chin J Exp Ophthalmol, 2024, 42(1): 19-28. Abstract                              [Download PDF] [Read Full Text] Objective To explore the effects of hyperoxic environments […]

Inhibitory effect of curcumin on malignant biological behavior and Wnt/β-catenin pathway of uveal melanoma cells

Authors: Sheng Xiaohong,  Wang Liming,  Zhao Xin,  Xin Xiangyang DOI: 10.3760/cma.j.cn115989-20220419-00170 Published 2024-01-10 Cite as Chin J Exp Ophthalmol, 2024, 42(1): 29-37. Abstract                              [Download PDF] [Read Full Text] Objective To explore the inhibitory effect of curcumin on the malignant biological behavior of […]

Mechanism of curcumin in the treatment of diabetic retinopathy based on network pharmacology and molecular docking

Authors: Du Yuanyuan,  Wang Yiyun,  Zhao Rong,  Zhang Ji,  Ji Xiaoyan,  Lu Jiayu,  Ji Fangfang,  Lou Hui,  Jiang Ziyuan,  Huang Jiang DOI: 10.3760/cma.j.cn115989-20220314-00105 Published 2023-12-10 Cite as Chin J Exp Ophthalmol, 2023, 41(12): 1152-1159. Abstract                              [Download PDF] [Read Full Text] Objective To […]

Inhibitory effect of indocyanine green on biological behavior and transdifferentiation of human lens epithelial cells and its mechanism

Authors: Liu Yajun,  Zhao Yingdi,  Zhang Wenwen,  Zhang Si,  He Zifang,  Chen Feifei,  Xie Zhenggao DOI: 10.3760/cma.j.cn115989-20220817-00380 Published 2023-12-10 Cite as Chin J Exp Ophthalmol, 2023, 41(12): 1160-1168. Abstract                              [Download PDF] [Read Full Text] Objective To investigate the inhibitory effect of indocyanine […]

Detrimental effects of soot from air pollution on tear film function in mice

Authors: Jiao Jingyi,  Liu Lin,  Xiao Kang,  Liu Qian,  Long Qin DOI: 10.3760/cma.j.cn115989-20221206-00573 Published 2023-11-10 Cite as Chin J Exp Ophthalmol, 2023, 41(11): 1059-1064. Abstract                            【Download PDF】 【Read Full Text】 Objective To observe the detrimental effect of airborne black carbon suspension solution of […]

Protective effect of COG1410 on the survival of retinal ganglion cells in mice with retinal ischemia-reperfusion injury and its mechanism

Authors: Zhao Ru,  Luo Jinyuan,  He Tao,  Xing Yiqiao DOI: 10.3760/cma.j.cn115989-20221116-00534 Published 2023-11-10 Cite as Chin J Exp Ophthalmol, 2023, 41(11): 1065-1075. Abstract                            【Download PDF】 【Read Full Text】 Objective To explore the effects of apolipoprotein E-mimetic peptide COG1410 on M1/M2 microglia polarization and […]

Dedifferentiation and regulation mechanism of TNF-α on orbital fibroblasts in thyroid-associated ophthalmopathy

Authors: Jing Yapeng,  Huang Xiaoming,  Wu Tong,  Jian Tianming,  Shi Shuangshuang,  Zhao Liang,  Sun Fengyuan,  Tang Dongrun DOI: 10.3760/cma.j.cn115989-20210119-00051 Published 2023-11-10 Cite as Chin J Exp Ophthalmol, 2023, 41(11): 1076-1083. Abstract                            【Download PDF】 【Read Full Text】 Objective To investigate the effect of tumor […]

Investigation of the tissue-damaging effects and mechanisms of neutrophil-derived MMP-8 in Fusarium keratitis

Authors: Dong Junlu,  Jin Xin,  Liu Hua,  Jian Shoujun,  Yue Juan,  Zhang Hongmin,  Wang Liya DOI: 10.3760/cma.j.cn115989-20210714-00412 Published 2023-10-10 Cite as Chin J Exp Ophthalmol, 2023, 41(10): 961-969. Abstract                              【Download PDF】 【Read Full Text】 Objective To investigate the mechanism of tissue damage […]

Inhibitory effect of miR-27b-3p and Nrf2 regulation on metabolic memory formation in human RPE cells

Authors: Lai Qiaoling,  Xie Ting,  Huang Yan DOI: 10.3760/cma.j.cn115989-20201208-00831 Published 2023-10-10 Cite as Chin J Exp Ophthalmol, 2023, 41(10): 970-979. Abstract                              【Download PDF】 【Read Full Text】 Objective To investigate the effect of microRNA-27b-3p (miR-27b-3p)/nuclear factor-E2-related factor 2 (Nrf2) on metabolic memory impairment […]

Inhibitory effect of GALNT2 gene knockdown on apoptosis of human retinal vascular endothelial cells in high glucose culture and its mechanism

Authors: Sun Tianyang,  Geriletu,  Zhang Yufeng,  Li Chunyu,  Jin Lin,  Bao Lingjun,  Wang Jiale DOI: 10.3760/cma.j.cn115989-20221207-00576 Published 2023-09-10 Cite as Chin J Exp Ophthalmol, 2023, 41(9): 846-853. Abstract                            【Download PDF】 【Read Full Text】 Objective To investigate the effect of polypeptide N-acetylgalactosaminaminyltransferase 2 (GALNT2) […]