Category: Experimental Science

Effects of lentivirus-mediated knockdown of astrocyte elevated gene-1 on the biological behavior of uveal melanoma

Authors: Mao Ying,  Bai Haixia,  Chang Ying,  Li Bin DOI: 10.3760/cma.j.issn.2095-0160.2018.10.003 Published 2018-10-10 Cite as Chin J Exp Ophthalmol, 2018,36(10): 748-755. Abstract                              [Download PDF] [Read Full Text] Objective To investigate the effects of lentivirus-mediated knockdown of astrocyte elevated gene-1 (AEG-1) on the biological behavior of uveal melanoma(UM). Methods MUM-2B […]

c-Fos expression in visual cortex of infant rhesus monkeys with myopia induced by hyperopic defocus

Authors: Wu Junshu,  Sha Xiangyin,  Zheng Hua,  Liu Yinghui,  Ge Jian DOI: 10.3760/cma.j.issn.2095-0160.2018.11.006 Published 2018-11-10 Cite as Chin J Exp Ophthalmol, 2018,36(11): 847-851. Abstract                               [Download PDF] [Read Full Text] Objective To observe c-Fos expression in visual cortex of infant rhesus monkeys with myopia induced by hyperopic defocus and preliminarily investigate […]

Changes of the immune-microenvironment in retinal degeneration process of RCS rat

Authors:  Tang Huanyu,  Lu Ziyang,  He Juncai,  Gao Yuan,  Yin Zhengqin DOI: 10.3760/cma.j.issn.2095-0160.2018.11.005 Published 2018-11-10 Cite as Chin J Exp Ophthalmol, 2018,36(11): 839-846. Abstract                               [Download PDF] [Read Full Text] Objective To explore the immune-microenvironment of the retinas at different stages of retinal degeneration in Royal College of Surgeon (RCS) rats. […]

Synergism of mesenchymal stem cells and low-dose cyclosporine A on corneal allograft rejection

Authors:  Jia Zhe,  Li Fei,  Lyu Ying,  Zeng Xiaoyu,  Lu Xiaoxiao,  Zhao Shaozhen DOI: 10.3760/cma.j.issn.2095-0160.2018.11.004 Published 2018-11-10 Cite as Chin J Exp Ophthalmol, 2018,36(11): 834-838. Abstract                              [Download PDF] [Read Full Text] Objective To investigate the effect of mesenchymal stem cells (MSCs) combined with low-dose cyclosporin A (CsA) […]

A new method for constructing engineered corneal epithelium based on embryonic stem cells

Authors: Qu Yangluowa,  Ou Shangkun,  Liu Tingting,  Zhang Liying,  Zou Dulei,  Li Juan,  He Hui,  Jia Changkai,  Zuo Chengyou,  Zhang Minjie,  He Xin,  Liu Zuguo,  Li Wei  DOI: 10.3760/cma.j.issn.2095-0160.2018.11.003 Published 2018-11-10 Cite as Chin J Exp Ophthalmol, 2018,36(11): 826-833. Abstract                               [Download PDF] [Read Full Text] Objective To construct engineered corneal epithelium from embryonic stem cells (ESCs) using Rock […]

The reaction pattern rules of mouse retinal ganglion cell under different wavelengths of light stimulation

Authors:  Lin Lixia,  Lou Bingsheng,  Yang Yao,  Zeng Jieting,  Lin Xiaofeng DOI: 10.3760/cma.j.issn.2095-0160.2018.12.007 Published 2018-12-10 Cite as Chin J Exp Ophthalmol, 2018,36(12): 931-935. Abstract                               [Download PDF] [Read Full Text] Objective To explore the reaction pattern rules of mouse retinal ganglion cells potential under different wavelengths of light stimulation. Methods Thirty […]

Inhibition of hepatocyte growth factor on proliferation and transdifferentiation of human Tenon capsule fibroblasts triggered by transforming growth factor-β1in vitro

Authors: Chen Jing,  Wang Yong,  Li Donghao DOI: 10.3760/cma.j.issn.2095-0160.2018.12.006 Published 2018-12-10 Cite as Chin J Exp Ophthalmol, 2018,36(12): 925-930. Abstract                              [Download PDF] [Read Full Text]           Objective To investigate the effects of hepatocyte growth factor (HGF) on proliferation and transdifferentiation […]

The protective effect of paeoniflorin in retina ischemia animal model through regulation of NLRP3 inflammasomes

Authors:  Yang Peiyao,  Zhao Jun,  Zhang Juanmei,  Gao Yunxia,  Zhan Weijiao,  Wang Yun,  Wang Qiang,  Xue Youyu  DOI: 10.3760/cma.j.issn.2095-0160.2018.12.005 Published 2018-12-10 Cite as Chin J Exp Ophthalmol, 2018,36(12): 920-924. Abstract                               [Download PDF] [Read Full Text] Objective To investigate the mechanisms of paeoniflorin in protection of retinal ischemia injury. Methods Fifty-four male specefic pathogen […]

The facilitation of corneal permeability of cyclosporine A loaded on chitosan-graft-cyclodextrin copolymers vector

Authors: Li Jingguo,  Zhou Tianyang,  Li Zhanrong,  Liang Zhen,  Xia Huiyun,  He Jijun,  Zhang Junjie DOI: 10.3760/cma.j.issn.2095-0160.2018.12.004 Published 2018-12-10 Cite as Chin J Exp Ophthalmol, 2018,36(12): 914-919. Abstract                               [Download PDF] [Read Full Text] Objective To investigate the corneal permeability of cyclosprin A (CsA) loaded on polymeric vector after topical application. Methods The […]

Comparision of the pharmacodynamics between different batches of recombinant decoy receptor innovative drug RC28-E in retinal vascular endothelial cells

Authors: Zheng Jialin,  Yang Qianhui,  Sun Jing,  Zhang Hong,  Jiang Jing,  Huang Min,  Li Shenjun,  Fang Jianmin,  Li Xiaorong,  Zhang Yan DOI: 10.3760/cma.j.issn.2095-0160.2018.12.003 Published 2018-12-10 Cite as Chin J Exp Ophthalmol, 2018,36(12): 908-913. Abstract                               [Download PDF] [Read Full Text] Objective To compare the protective effects of pharmacological batch RC28-E1 and pilot batch RC28-E2 on retinal […]