Authors: Hu Xinxin, Dai Yi, Sun Xinghuai DOI: 10.3760/cma.j.issn.2095-0160.2018.07.003 Published 2018-07-10 Cite as Chin J Exp Ophthalmol, 2018,36(7): 494-499. Abstract [Download PDF] [Read Full Text] Objective To investigate the ultrastructural changes of mitochondria and dynamic changes of mitochondrial dynamics related genes in chronic ocular hypertension rat models. Methods […]
Category: Experimental Science
Effect of Eylea on recombinant AAV2-VEGF-induced choroidal neovascularization
Authors: Jiang Laisheng, Liao Qin, Cai Keyang, Sun Huiye, Sun Yunxia DOI: 10.3760/cma.j.issn.2095-0160.2018.08.008 Published 2018-08-10 Cite as Chin J Exp Ophthalmol, 2018,36(8): 608-612. Abstract [Download PDF] [Read Full Text] Objective To evaluate the effect of Eylea (aflibercept) on recombinant adeno-associated virus 2(AAV2)-vascular endothelial growth factor (VEGF)-induced choroidal neovascularization (CNV). Methods […]
The suppression mechanisms of quercetin in retinal and choroidal neovascularization through integrin signal pathway
Authors: Yue Yankun, Wang Haiwei, Deng Yu, Tian Mo, Wang Yinlin, Zhang Enkui DOI: 10.3760/cma.j.issn.2095-0160.2018.08.007 Published 2018-08-10 Cite as Chin J Exp Ophthalmol, 2018,36(8): 602-607. Abstract [Download PDF] [Read Full Text] Objective To investigate the mechanisms of quercetin in retinal angiogenesis via in vitro and in vivo studies. Methods Human umbilical […]
The dynamic expression of CD146 in corneal neovascularization and its significance
Authors: Wang He, Li Mingxin DOI: 10.3760/cma.j.issn.2095-0160.2018.08.005 Published 2018-08-10 Cite as Chin J Exp Ophthalmol, 2018,36(8): 596-600. Abstract [Download PDF] [Read Full Text] Objective To investigate the expression and localization of CD146 in corneal neovascularization. Methods Fifty SPF male SD rats with the […]
Changes of Kir4.1 and TASK-1 expression in rat Müller cell induced by SCH442416 at an elevated hydrostatic pressure in vitro
Authors: Yang Zijian, Cheng Yu, Yao Huiping, Shen Ting, Chen Yanwei, Zhong Yisheng DOI: 10.3760/cma.j.issn.2095-0160.2018.08.003 Published 2018-08-10 Cite as Chin J Exp Ophthalmol, 2018,36(8): 590-594. Abstract [Download PDF] [Read Full Text] Objective To evaluate the effect of adenosine receptor antagonist SCH442416 on the expression of Kir2.1, Kir4.1 and TASK-1 in rat […]
Comparison of pharmacodynamics between different batches of recombinant decoy receptor innovative drug RC28-E1 and RC28-E2 in retinal angiogenesis and neovascularization and its mechanism
Authors: Gu Zhongxiu, Jiang Jing, Huang Min, Wu Mianmian, Guo Fang, Li Shenjun, Fang Jianmin, Zhao Shaozhen, Zhang Yan DOI: 10.3760/cma.j.issn.2095-0160.2018.08.002 Published 2018-08-10 Cite as Chin J Exp Ophthalmol, 2018,36(8): 581-589. Abstract [Download PDF] [Read Full Text] Objective To compare the pharmacodynamics between different batches of recombinant decoy receptor innovative drug RC28-E1 and RC28-E2 […]
Growth characteristics of Aspergillus isolated from clinical infective cornea
Authors: Li Yingyu, Zhang Pei, Huang Chen, Liu Ziyuan, Liu Cong, Zhang Wei, Dong Xuhe, Wang Wei DOI: 10.3760/cma.j.issn.2095-0160.2018.09.006 Published 2018-09-10 Cite as Chin J Exp Ophthalmol, 2018,36(9): 683-687. Abstract [Download PDF] [Read Full Text] Objective To analyze the growth characteristics of the clinical isolates of Aspergillus compared to standard strains in vitro. […]
Expression of p53 and its effect on microRNA-29b expression in the process of normal human conjunctival fibroblasts transforming to myofibroblast
Authors: Yan Weiling, Liao Rongfeng, Li Ning DOI: 10.3760/cma.j.issn.2095-0160.2018.09.004 Published 2018-09-10 Cite as Chin J Exp Ophthalmol, 2018,36(9): 676-681. Abstract [Download PDF] [Read Full Text] Objective To investigate the relationship between p53 and miR-29b in myofibroblasts (MFs) induced from human Tenon fibroblasts (HTFs). Methods Human Tenon tissues were […]
Establishment of apoptosis model in mouse cone cell line 661W cells and the primary research on protective effects of autophagy
Authors: Gao Wenna, Xie Jia, Du Jiantong, Zhu Ruilin, Yang Liu DOI: 10.3760/cma.j.issn.2095-0160.2018.09.003 Published 2018-09-10 Cite as Chin J Exp Ophthalmol, 2018,36(9): 666-675. Abstract [Download PDF] [Read Full Text] Objective To establish the apoptosis model in mouse cone cell line 661W cells and to investigate the viability of 661W cells […]
Pulsed and continuous accelerated scleral cross-linking using riboflavin and ultraviolet A irradiation for the prevention of myopia progression in a guinea pig model
Authors: Xu Haiming, Liu Hui, Yu Jie, He Jinjing DOI: 10.3760/cma.j.issn.2095-0160.2018.10.006 Published 2018-10-10 Cite as Chin J Exp Ophthalmol, 2018,36(10): 767-772. Abstract [Download PDF] [Read Full Text] Objective To evaluated the effect of oral administration of riboflavin combined with pulsed and continuous light accelerated scleral cross-linking on the histological […]