Category: Experimental Science

Preventive and therapeutic effects of resveratrol on lens opacification in diabetic rats and its mechanism

Authors: Ge Xiaofang,  Zhu Daqiang,  Liu Yadong,  Luo Nali DOI: 10.3760/cma.j.cn115989-20200922-00660 Published 2023-06-10 Cite as Chin J Exp Ophthalmol, 2023, 41(6): 545-553. Abstract                              [Download PDF] [Read Full Text] Objective To investigate the preventive and therapeutic effects of resveratrol on lens opacification in […]

Regulatory effect of CCCTC binding factor on Bcl-2 gene in pterygium and its mechanism

Authors: Yin Xiuqin,  Yu Li,  Yi Lu,  Fang Jiahua DOI: 10.3760/cma.j.cn115989-20211108-00611 Published 2023-05-10 Cite as Chin J Exp Ophthalmol, 2023, 41(5): 421-427. Abstract                              [Download PDF] [Read Full Text] Objective To investigate the regulation of transcription factor CCCTC binding factor (CTCF) on the […]

Inhibitory effect of astaxanthin on oxidative stress damage in lens epithelial cells and its mechanism

Authors: Li Yong,  Liu Zhaochen,  Peng Huacong DOI: 10.3760/cma.j.cn115989-20200624-00448 Published 2023-05-10 Cite as Chin J Exp Ophthalmol, 2023, 41(5): 428-435. Abstract                              [Download PDF] [Read Full Text] Objective To investigate the regulatory effect of astaxanthin on oxidative stress injury induced by hydrogen peroxide […]

Comparison of ocular microbiomes between patients with and without dry eye

Authors: Song Yu,  Qi Yun,  Zhang Ming,  Kang Qianyan,  Li Li DOI: 10.3760/cma.j.cn115989-20211228-00718 Published 2023-05-10 Cite as Chin J Exp Ophthalmol, 2023, 41(5): 436-441. Abstract                              [Download PDF] [Read Full Text] Objective To explore the difference in ocular surface microbiota between patients with […]

Inhibition of roscovitine on the activity of Cdk5/p25 and phosphorylation of tau in retina of RCS rats after intravitreal injection

Authors: Zhang Jinjin,  Sheng Xunlun,  Ren Yinghua,  Rong Weining,  Li Huiping,  Liu Yani DOI: 10.3760/cma.j.issn.2095-0160.2015.01.002 Published 2015-01-10 Cite as Chin J Exp Ophthalmol, 2015,33(1): 5-9. Abstract                              [Download PDF] [Read Full Text] Background Study determined that retinitis pigmentosa has a similar pathogenesis mechanism […]

Regulation of microRNA to the expression of matrix metalloproteinases in bone marrow-derived cells in mice with choroidal neovascularization

Authors: Lyu Yang,  Hou Huiyuan,  Wang Yusheng DOI: 10.3760/cma.j.issn.2095-0160.2015.01.003 Published 2015-01-10 Cite as Chin J Exp Ophthalmol, 2015,33(1): 10-15. Abstract                              [Download PDF] [Read Full Text] Background Matrix metalloproteinases (MMPs) play important roles in the formation of choroidal neovascularization (CNV), but its mail […]

Mitochondrial pathway of retinal pigment epithelial cell apoptosis induced by blue light in vitro

Authors: Li Hong,  Lyu Jianping,  Cai Shanjun,  Su Gang,  Wu Zhipeng,  Gong Xin DOI: 10.3760/cma.j.issn.2095-0160.2015.01.004 Published 2015-01-10 Cite as Chin J Exp Ophthalmol, 2015,33(1): 16-20. Abstract                              [Download PDF] [Read Full Text] Background Studies determined that blue light exposure causes apoptosis of human […]

Epithelial-mesenchymal transition of human retinal pigment epithelial cells under the high glucose condition in vitro

Authors: Hou Dingshan,  Li Ruishu,  Fan Yan,  Bi Wenjiao,  Zhang Xiaomei DOI: 10.3760/cma.j.issn.2095-0160.2015.01.005 Published 2015-01-10 Cite as Chin J Exp Ophthalmol, 2015,33(1): 21-26. Abstract                              [Download PDF] [Read Full Text] Background Several types of cells participate in the formation of proliferative membrane in […]

Inhibitory effect of ursolic acid on high oxygen-induced mouse retinal neovascularization by intravitreal injection

Authors: He Ling,  Zheng Xiaolong,  Zhang Jie,  Zhang Shanfeng,  Yu Xiaohong,  Tian Fang DOI: 10.3760/cma.j.issn.2095-0160.2015.01.006 Published 2015-01-10 Cite as Chin J Exp Ophthalmol, 2015,33(1): 27-32. Abstract                             [Download PDF] [Read Full Text] Background Retinal neovascular diseases affect visual function.Although many drugs have been used […]

Promoting proliferation and inhibiting apoptosis effects of sphingosine-1-phospate on human retinal pigment epithelium cells under the hypoxic condition

Authors: Fan Yan,  Lu Hong,  Hou Dingshan,  Bi Wenjiao,  Zhang Xiaomei DOI: 10.3760/cma.j.issn.2095-0160.2015.01.007 Published 2015-01-10 Cite as Chin J Exp Ophthalmol, 2015,33(1): 33-37. Abstract                            [Download PDF] [Read Full Text] Background Sphingosine-1-phospate (S1P) is a bioactive lipid and important messenger molecule in cells.It participates […]