Tag: animal

Experimental study on inhibiting graft rejection following high-risk cornea transplatation by resolvinE1 in mice

Authors: Wang Han,  Luo Dan,  Li Ting,  Zhao Min DOI: 10.3760/cma.j.issn.2095-0160.2017.03.005 Published 2017-03-10 Cite as Chin J Exp Ophthalmol, 2017,35(3): 209-215. Abstract                               [Download PDF] [Read Full Text] Background The conventional drugs for preventing and treating graft rejection have the risks of inducing adverse responses.Researches showed that resolvinE1 (RvE1) can […]

Dynamic expression changes of Smad3 and type Ⅰ collagen in sclera of progressive myopia in guinea pigs

Authors: Jiang Bo,  Wu Zhangyou,  Zhu Zicheng,  Hu Wei,  Zhan Xin DOI: 10.3760/cma.j.issn.2095-0160.2017.06.003 Published 2017-06-10 Cite as Chin J Exp Ophthalmol, 2017,35(06): 491-497. Abstract                              [Download PDF] [Read Full Text] Background Sclera remodeling process in axial elongation is one of the main pathological mechanisms of axial myopia progression.Studies confirmed that transforming […]

Inflammatory-promoting roles of thymic stromal lymphopoietin and interleukin-4 in allergic conjunctivitis mice

Authors: Ning Chanhui,  Zheng Xiaofen,  Li Bing DOI: 10.3760/cma.j.issn.2095-0160.2017.09.009 Published 2017-09-10 Cite as Chin J Exp Ophthalmol, 2017,35(9): 811-815. Abstract                              [Download PDF] [Read Full Text] Background Researches showed that thymic stromal lymphopoietin (TSLP) is an interleukin-17-like inflammatory factor and plays important roles in the pathogenesis and development of […]

Inflammation-causing effects and mechanism of natural killer cells in experimental autoimmune uveitis rats

Authors: Li Mohan,  Bao Ning,  Liu Dongwei,  Tao Liming,  Jiang Zhengxuan DOI: 10.3760/cma.j.issn.2095-0160.2017.09.007 Published 2017-09-10 Cite as Chin J Exp Ophthalmol, 2017,35(9): 799-804. Abstract                              [Download PDF] [Read Full Text] Background Experimental autoimmune uveitis (EAU) is a common animal model of uveitis.Natural killer (NK) cells have been confirmed to be a […]

Dynamic expression and mechanism of γδ T cells in the spleen of mouse with experimental autoimmune uveitis

Authors: Wang Beibei,  Tian Qingmei,  Xie Xiaofeng,  Song Jike,  Bi Hongsheng DOI: 10.3760/cma.j.issn.2095-0160.2017.09.006 Published 2017-09-10 Cite as Chin J Exp Ophthalmol, 2017,35(9): 793-798. Abstract                              [Download PDF] [Read Full Text] Background Previous studies showed that the pathogenesis of uveitis is related to γδ T cells.However, it remains unclear that how these […]

Degeneration of short-wavelength cone cells in rd12 mice

Authors: Li Xia,  Zhang Hua,  Dai Xufeng,  Pang Jijing DOI: 10.3760/cma.j.issn.2095-0160.2017.11.003 Published 2017-11-10 Cite as Chin J Exp Ophthalmol, 2017,35(11): 970-975. Abstract                              [Download PDF] [Read Full Text] Background Retinitis pigmentosa (RP) is one of the causes of congenital blindness.It is well known that the degeneration process of rod cells […]

Inhibitory effects of bevacizumab on corneal neovascularization and scarring in mice with herpes simplex keratitis

Authors: Zhou Hongwei,  Wang Tongsong,  Zhang Songmei,  Xie Lixin DOI: 10.3760/cma.j.issn.2095-0160.2017.12.007 Published 2017-12-10 Cite as Chin J Exp Ophthalmol, 2017,35(12): 1085-1091. Abstract                               [Download PDF] [Read Full Text] Background Corneal neovascularization and inflammation occur in herpes simplex keratitis (HSK). Aciclovir (ACV) is an antiviral medication which is primarily used for […]

Animal models of oxygen-induced retinopathy

Authors: Yang Ning,  Xing Yiqiao DOI: 10.3760/cma.j.issn.2095-0160.2018.01.013 Published 2018-01-10 Cite as Chin J Exp Ophthalmol, 2018,36(1): 61-64. Abstract                              [Download PDF] [Read Full Text] Models of oxygen-induced retinopathy (OIR) have been built on several animals, including kitten, mouse, rat, rabbit, puppy and zebrafish.These models play an important role in […]

Promoting repair effects of chitosan/gelatin electrospinning membrane implantation on rabbit conjunctival injury

Authors: Zheng Yuqiang,  Wang Zhuoshi,  Xu Ling,  Wang Liansong,  He Wei DOI: 10.3760/cma.j.issn.2095-0160.2018.02.006 Published 2018-02-10 Cite as Chin J Exp Ophthalmol, 2018,36(2): 102-106. Abstract                              [Download PDF] [Read Full Text] Objective To investigate the promoting repair effects of chitosan/gelatin electrospinning membrane implantation on conjunctival injury. Methods Chitosan/gelatin electrospinning membrane was prepared […]

Protective effects of carnosic acid on retinal ganglion cells in acute ocular hypertension rats model

Authors:  He Liye,  Liang Liang,  Zhu Mengnan,  Xiao Changyi,  Tu Xiaokun DOI: 10.3760/cma.j.issn.2095-0160.2018.04.005 Published 2018-04-10 Cite as Chin J Exp Ophthalmol, 2018,36(4): 254-258. Abstract                               [Download PDF] [Read Full Text] Objective To observe the protective effects of carnosic acid on retinal ganglion cells (RGCs) in acute ocular hypertension rats model. Methods […]