Authors: Tang Jia, Chen Youxin DOI: 10.3760/cma.j.issn.2095-0160.2020.01.013 Published 2020-01-10 Cite as Chin J Exp Ophthalmol, 2020,38(01): 64-67. Abstract [View PDF] [Read Full Text] Vascular endothelial growth factor(VEGF), also known as vascular permeability factor, can promote the proliferation and migration of vascular endothelial cells, and enhance vascular […]
Tag: Vascular endothelial growth factor
MicroRNA in tumor angiogenesis and target therapy
Authors: Yang Jingyan, Wei Wenbin DOI: 10.3760/cma.j.issn.2095-0160.2019.12.018 Published 2019-12-10 Cite as Chin J Exp Ophthalmol, 2019,37(12): 1037-1040. Abstract [View PDF] [Read Full Text] Angiogenesis is a complex process and plays an important role in tumor growth and metastasis.Among the factors of angiogenesis, vascular endothelial growth factor […]
Expression of proline hydroxylase 2 in the membrane of proliferative diabetic retinopathy
Authors: Zhang Han, Lu Qiang, Cui Wei DOI: 10.3760/cma.j.issn.2095-0160.2019.10.003 Published 2019-10-10 Cite as Chin J Exp Ophthalmol, 2019,37(10): 779-784. Abstract [View PDF] [Read Full Text] Objective To investigate the expression of proline hydroxylase 2 (PHD2) in the proliferatine membrane of proliferative diabetic retinopathy (PDR) and its relationship with […]
Inhibition of PTB-associated splicing factor on IGF-1/VEGF signaling pathway in retinal vascular endothelial cells
Authors: Tian Fang, Dong Lijie, Ji jie, Zhou Yu, Li Wenbo, Bai Lingling, Wang Fei, Qi Chen, Su Chang, Zhang Xiaomin, Li Xiaorong DOI: 10.3760/cma.j.issn.2095-0160.2016.01.003 Published 2016-01-10 Cite as Chin J Exp Ophthalmol, 2016,34(1): 11-16. Abstract [Download PDF] [Read Full Text] Background Retinal neovascularization (RNV) is common findings of many fundus diseases.Research showed that insulin-like growth factor-1 […]
Inhibition of CCN1 siRNA on retinal endothelial cells
Authors: Di Yu, Zhang Yiou, Wang Aiyuan, Chen Xiaolong DOI: 10.3760/cma.j.issn.2095-0160.2016.01.005 Published 2016-01-10 Cite as Chin J Exp Ophthalmol, 2016,34(1): 24-29. Abstract [Download PDF] [Read Full Text] Background Cysteine-rich 61(Cyr61)/CCN1 has been reported to stimulate retinal neovascularization (RNV) in retinopathy of prematurity (ROP). However, whether CCN1 small interfering RNA […]
Inhibition of ADP-ribosylation factor antagonist on human retinal vascular endothelial cell tube formation in vitro
Authors: Wu Jing, Liu Gaoqin, Chen Zhigang, Xiao Yanhui, Xu Jing, Lu Peirong DOI: 10.3760/cma.j.issn.2095-0160.2016.01.006 Published 2016-01-10 Cite as Chin J Exp Ophthalmol, 2016,34(1): 30-34. Abstract [Download PDF] [Read Full Text] Background Researches showed that ADP-ribosylation factor (ARF) promotes intracorneal secretion of multiple angiogenesis-related factors, such as vascular endothelial growth factor (VEGF) […]
The changes of aqueous humor vascular endothelial growth factor and pigment epithelium-derived factor levels before and after intravitreal injection of ranibizumab in proliferative diabetic retinopathy
Authors: Wang Yunpeng, Chen Xiaohong, Chen Meizhu DOI: 10.3760/cma.j.issn.2095-0160.2016.01.012 Published 2016-01-10 Cite as Chin J Exp Ophthalmol, 2016,34(1): 60-64. Abstract [Download PDF] [Read Full Text] Background Intraocular neovascularization is a primary cause of visual reduce in proliferative diabetic retinopathy (PDR), and intravitreal injection of ranibizumab is one of […]
Research progress of vascular endothelial growth factor inhibitor in the treatment of corneal neovascularization
Authors: Lin Tianlan, Zhou Shanbi DOI: 10.3760/cma.j.issn.2095-0160.2016.04.018 Published 2016-04-10 Cite as Chin J Exp Ophthalmol, 2016,34(4): 371-374. Abstract [Download PDF] [Read Full Text] Normal cornea is avascular, fully transparent organization, which is important to the eye refraction.However, many eye diseases can destroy the anti-angiogenic factor and […]
Progress on Nrf2 pathway in diabetic retinopathy
Authors: Zhang Siyuan, Lyu Hongbin DOI: 10.3760/cma.j.issn.2095-0160.2016.05.017 Published 2016-05-10 Cite as Chin J Exp Ophthalmol, 2016,34(5): 471-475. Abstract [Download PDF] [Read Full Text] Diabetic retinopathy (DR) is a serious complication of diabetes mellitus, which leads to vision loss or even blindness.Nuclear factor erythroid 2-related factor 2 […]
Protecting effects and mechanism of tert-butyl hydroquinone on retinal cells in type 2 diabetic rats
Authors: Han Peiyan, Zhang Siyuan, Li Jingyan, Huang Qi, Tian Min, Lyu Hongbin DOI: 10.3760/cma.j.issn.2095-0160.2016.06.004 Published 2016-06-10 Cite as Chin J Exp Ophthalmol, 2016,34(6): 496-502. Abstract [Download PDF] [Read Full Text] Background Apoptosis is a primary clinical pathological mechanism of diabetic retinopathy […]