Authors: Xu Wen, Li Shuyi DOI: 10.3760/cma.j.issn.2095-0160.2016.03.001 Published 2016-03-10 Cite as Chin J Exp Ophthalmol, 2016,34(3): 193-198. Abstract [Download PDF] [Read Full Text] Cataract is still the main blinding eye disease, and it is a major goal of fighting blindness in China.In the past years, the diagnosis, […]
Category: 2016, No. 03
Construction of Smac siRNA lentiviral vector and its silencing effect on Smac gene in human LECs
Authors: Li Yun, Zheng Guangying, Jiang Yu DOI: 10.3760/cma.j.issn.2095-0160.2016.03.002 Published 2016-03-10 Cite as Chin J Exp Ophthalmol, 2016,34(3): 199-204. Abstract [Download PDF] [Read Full Text] Background Research comfirmed that second mitochondrial activator of caspase (Smac) is a promoting tumor cell apoptosis protein.Our previous study showed that the expression […]
Expression and its significance of aquaporin0 and 1 in lens with age-related cataract
Authors: Zhan Zhiyun, Xu Guoxing, Xie Maosong DOI: 10.3760/cma.j.issn.2095-0160.2016.03.003 Published 2016-03-10 Cite as Chin J Exp Ophthalmol, 2016,34(3): 205-209. Abstract [Download PDF] [Read Full Text] Background Age-related cataract is a common cause of blindness.However, its cause and pathogenic mechanism have not been fully understood.Recent studies revealed that aquaporin 1 […]
In vitro epithelial-mesenchymal transition model for LECs of human posterior capsule opacification
Authors: Yang Baoxia, Wang Ye, Zhao Xiaowen, Liu Ting, Huang Yusen DOI: 10.3760/cma.j.issn.2095-0160.2016.03.004 Published 2016-03-10 Cite as Chin J Exp Ophthalmol, 2016,34(3): 210-217. Abstract [Download PDF] [Read Full Text] Background Epithelial-mesenchymal transition (EMT) is one of the pathogenesis mechanisms of posterior capule opcification (PCO). Studying EMT is of important significance […]
The regulation of estradiol on growth dynamics of human LECs affected by increasing telomerase activity
Authors: Wang Jie, Kang Gangjin, Yuan Xuefeng, Xu Manhua, Jiang Yan, Luo Bo DOI: 10.3760/cma.j.issn.2095-0160.2016.03.006 Published 2016-03-10 Cite as Chin J Exp Ophthalmol, 2016,34(3): 219-225. Abstract [Download PDF] [Read Full Text] Background Human LECs can express telomerase activity, which participates in the formation of cataract.It is reported that estrogen can increase […]
Anti-oxydative effects of miR-204 on LECs in age-related cataract
Authors: Su Xianhua, Wang Ye, Huang Yusen DOI: 10.3760/cma.j.issn.2095-0160.2016.03.008 Published 2016-03-10 Cite as Chin J Exp Ophthalmol, 2016,34(3): 227-233. Abstract [Download PDF] [Read Full Text] Background miRNAs are a group of non-coding small RNA molecules, and they play an important role in regulating the apoptosis of LECs.The biological effects […]
Negative regulation of exogeneous polyl-4-hydroxylase domain proteins on hypoxia-inducible factor pathway in human RPE cells
Authors: Ma Yu, Tang Shaohua, Jiang Yanrong, Shi Xuan DOI: 10.3760/cma.j.issn.2095-0160.2016.03.009 Published 2016-03-10 Cite as Chin J Exp Ophthalmol, 2016,34(3): 234-238. Abstract [Download PDF] [Read Full Text] Background Anti-VEGF drugs are generally applied in the treatment of ocular neovascular diseases.However, the therapy effect is unsatisfactory […]
Clinical outcomes and safety of intra-capsular bag soft-shell technique during phacoemulsification for hard nuclear cataract
Authors: Han Wei, Chen Binchuan, Li Jiajia DOI: 10.3760/cma.j.issn.2095-0160.2016.03.010 Published 2016-03-10 Cite as Chin J Exp Ophthalmol, 2016,34(3): 239-243. Abstract [Download PDF] [Read Full Text] Background Phacoemulsification for hard nuclear cataract is easy to cause corneal edema and posterior capsular rupture.Researches determined that soft-shell technique phacoemulsification can effectively […]
Identification of novel compound heterozygous mutations of USH2A gene in a RP pedigree by targeted-capture next generation sequencing
Authors: Wang Ying, Huang Hui, Fan Ning, Wu Jing, Zhou Xiaomin, Yin Yan, Wang Yun, Liu Xuyang DOI: 10.3760/cma.j.issn.2095-0160.2016.03.011 Published 2016-03-10 Cite as Chin J Exp Ophthalmol, 2016,34(3): 244-247. Abstract [Download PDF] [Read Full Text] Background RP is the term given to a set of hereditary retinal diseases.RP has […]
Optical quality evaluation of pseudophakic eyes implanted different materials of IOL by optical quality analysis system
Authors: Wei Yinjuan, Song Hui, Tang Xin DOI: 10.3760/cma.j.issn.2095-0160.2016.03.012 Published 2016-03-10 Cite as Chin J Exp Ophthalmol, 2016,34(3): 248-253. Abstract [Download PDF] [Read Full Text] Background Phacoemulsification with IOL implantation can reduce the light scattering caused by cataract, but many patients with IOLs implantation complained of glare or […]