Category: Experimental Science

Effect of long-term topical administration of prostaglandins on bulbar conjunctival thickness in rabbits

Authors: Ma Kai,  Yin Chengjuan,  Zhang Zhenyong DOI: 10.3760/cma.j.cn115989-20200707-00481 Published 2021-10-10 Cite asChin J Exp Ophthalmol, 2021, 39(10): 857-862. Abstract                              [View PDF] [Read Full Text] Objective To investigate the effect of long-term application of prostaglandin analog drops on bulbar conjunctival thickness in rabbits. Methods Twenty-four […]

Studies on the mechanism of inhibitory effect of lithium chloride on the proliferation of human Tenon capsule fibroblasts

Authors: Zou Huihui,  Liu Shanshan,  Liang Ling,  Fan Xiaojun,  Wang Jibing DOI: 10.3760/cma.j.cn115989-20200324-00196 Published 2021-10-10 Cite asChin J Exp Ophthalmol, 2021, 39(10): 863-868. Abstract                              [View PDF] [Read Full Text] Objective To investigate the effect of lithium chloride (LiCl) on the gap junctional intercellular communication (GJIC) […]

Evaluation of low-quality fundus image enhancement based on cycle-constraint adversarial network

Authors: Zhou Xueting,  Yang Weihua,  Hua Xiao,  You Qijing,  Sun Jing,  Shen Jianxin,  Wan Cheng DOI: 10.3760/cma.j.cn115989-20201028-00718 Published 2021-09-10 Cite asChin J Exp Ophthalmol, 2021, 39(9): 769-775. Abstract                              [View PDF] [Read Full Text] Objective To propose and evaluate the cycle-constraint adversarial network (CycleGAN) for enhancing […]

Regulatory effect of edaravone on the photoreceptor autophagy at the early stage of experimental retinal detachment in rats

Authors: Kang Ziwei,  Ren Xiuyu,  Zhang Yanchun,  Pei Cheng,  Zhang Nana,  Xia Yimin,  Yang Jingru DOI: 10.3760/cma.j.cn115989-20200228-00123 Published 2021-09-10 Cite asChin J Exp Ophthalmol, 2021, 39(9): 776-784. Abstract                              [View PDF] [Read Full Text] Objective To investigate the effect of edaravone, a free radical scavenger, on […]

Evaluation of multi-classification method of color fundus photograph quality based on ResNet50-OC

Authors: Wan Cheng,  Zhou Xueting,  You Qijing,  Shen Jianxin,  Yu Qiuli DOI: 10.3760/cma.j.cn115989-20200107-00011 Published 2021-09-10 Cite asChin J Exp Ophthalmol, 2021, 39(9): 785-790. Abstract                              [View PDF] [Read Full Text] Objective To evaluate the efficiency of ResNet50-OC model based on deep learning for multiple classification of […]

Expression of lncRNA Tsix in a mouse model of N-methyl-D-aspartic acid-induced retinal excitotoxicity and its significance

Authors: Li Yahong,  Geng Chao,  Hei Kaiwen,  Liu Shengnan,  Wang Qi,  Li Xiaorong,  Zhang Yan DOI: 10.3760/cma.j.cn115989-20200119-00033 Published 2021-08-10 Cite asChin J Exp Ophthalmol, 2021, 39(8): 676-685. Abstract                              [View PDF] [Read Full Text] Objective To investigate the damage effect of different concentrations of N-methyl-D-aspartic acid […]

Bioinformatics analysis of transcriptome sequencing after the interference of extremely low frequency electromagnetic field in mouse fibroblasts

Authors: Zhu Maolin,  Zhu Huang DOI: 10.3760/cma.j.cn115989-20200905-00633 Published 2021-08-10 Cite asChin J Exp Ophthalmol, 2021, 39(8): 686-692. Abstract                              [View PDF] [Read Full Text] Objective To analyze the changes in the transcriptome of mouse fibroblasts after exposure to extremely low frequency electromagnetic fields (ELF-EMFs) using next-generation […]

Protective effect of adeno-associated virus vector mediated heme oxygenase-1 overexpression on retinitis pigmentosa in rats

Authors: Liang Yuping,  Chen Weiqi,  Hong Yu,  Gao Xiuyun,  Guo Maosheng DOI: 10.3760/cma.j.cn115989-20201108-00754 Published 2021-08-10 Cite asChin J Exp Ophthalmol, 2021, 39(8): 693-699. Abstract                              [View PDF] [Read Full Text] Objective To investigate the protective effect of adeno-associated virus (AAV) vector-mediated heme oxygenase-1 (HO-1) gene overexpression […]

Relationship between BAP1, FOXO3 and ITPR2 gene expression and metastasis and prognosis of uveal melanoma

Authors: Li Yang,  Feng Yu,  Liu Yueming,  Wei Wenbin DOI: 10.3760/cma.j.cn115989-20200714-00495 Published 2021-08-10 Cite asChin J Exp Ophthalmol, 2021, 39(8): 700-707. Abstract                              [View PDF] [Read Full Text] Objective To explore the potential biomarkers for the metastasis and prognosis of uveal melanoma (UM) from molecular genetics. […]

Protective effect and mechanism of cx3cr1 antibody intravitreal injection in microcirculation of retinal ischemia-reperfusion injury in mice

Authors: Li Juanjuan,  Chen Chen,  Li Yan,  Zhang Liwei DOI: 10.3760/cma.j.cn115989-20200104-00004 Published 2021-07-10 Cite asChin J Exp Ophthalmol, 2021, 39(7): 585-592. Abstract                              [View PDF] [Read Full Text] Objective To investigate the protective effect of C-X3-C motif chemokine receptor 1 (cx3cr1) antibody, a microglia activation inhibitor, […]