Authors: Zhang Fang, Xu Xun DOI: 10.3760/cma.j.cn115989-20211209-00678 Published 2022-01-10 Cite asChin J Exp Ophthalmol, 2022, 40(1): 1-5. Abstract Diabetes mellitus (DM) is a chronic metabolic disease caused by multiple etiologies. Diabetic retinopathy (DR), as a primary ocular complication of DM, is the leading cause of blindness among working-age adults in the world.With the rapid increase […]
Category: 2022, No. 01
Effect of ROS/NLRP3/Caspase-1 signaling pathway on the apoptosis of retinal pigment epithelial cells induced by high glucose
Authors: Li Hongsong, Li Rong, Wang Lijun, Liao Dingying, Wang Jianming DOI: 10.3760/cma.j.cn115989-20210420-00267-1 Published 2022-01-10 Cite asChin J Exp Ophthalmol, 2022, 40(1): 6-12. Abstract Objective To investigate the effect of the nucleotide-binding domain, leucine-rich-containing family, pyrin domain-containing 3 (NLRP3) inflammasome on the proliferation and apoptosis of human retinal pigment epithelial cell line ARPE-19 exposed to […]
Proteomic analysis of optic nerve in the rat model of non-arteritic anterior ischemic optic neuropathy
Authors: Hu Liying, Li Zhiqing, Shao Xianfeng, Guo Xiaoxue, Yu Dawei, Dong Lijie, Li Xiaorong DOI: 10.3760/cma.j.cn115989-20201104-00745 Published 2022-01-10 Cite asChin J Exp Ophthalmol, 2022, 40(1): 13-20. Abstract Objective To quantitatively analyze the protein expression changes of the optic nerve in an SD rat model of non-arteritic anterior ischemic optic neuropathy (NAION), and to make […]
Effect of human umbilical cord derived mesenchymal stem cells on apoptosis of rat retinal ganglion cells under high glucose and on the regulation of p38MAPK pathway
Authors: Liu Xi, Sun Xiaoping, Yang Jianwei, Zhu Dongmei, Wang Yuan DOI: 10.3760/cma.j.cn115989-20200804-00559 Published 2022-01-10 Cite asChin J Exp Ophthalmol, 2022, 40(1): 21-28. Abstract Objective To investigate the effect of human umbilical cord mesenchymal stem cells (hUC-MSC) on the apoptosis of retinal ganglion cells (RGCs) in diabetic retinopathy (DR) model rats and on the regulation […]
Expression and significance of Jagged1 in fibrovascular membranes of proliferative diabetic retinopathy
Authors: Guo Qingmin, Meng Xuxia, Yang Kun, Yu Chuan DOI: 10.3760/cma.j.cn115989-20191018-00453 Published 2022-01-10 Cite asChin J Exp Ophthalmol, 2022, 40(1): 29-34. Abstract Objective To observe the expression and significance of Jagged1 in fibrovascular membranes of proliferative diabetic retinopathy (PDR). Methods Sixty preretinal fibrovascular membrane specimens collected from fifty-seven patients (60 eyes) with PDR during vitrectomy […]
Application value assessment of intraoperative optical coherence tomography in vitreoretinal surgery
Authors: Tao Jiwei, Chen Huan, Shen Lijun, Lin Jingjing, Chen Yiqi, Mao Jianbo, Fang Jia DOI: 10.3760/cma.j.cn115989-20190715-00309 Published 2022-01-10 Cite asChin J Exp Ophthalmol, 2022, 40(1): 35-40. Abstract Objective To evaluate the application of intraoperative optical coherence tomography (iOCT) in vitreoretinal surgery. Methods An observational case series study was conducted.A total of 316 patients (316 […]
Comparison of efficacy between intravitreal injection of conbercept with and without macular photocoagulation for diabetic macular edema
Authors: Jiang Li, Luo Xiaoling, Qin Bo, Deng Tingming, Yang Mingming DOI: 10.3760/cma.j.cn115989-20201104-00746 Published 2022-01-10 Cite asChin J Exp Ophthalmol, 2022, 40(1): 41-46. Abstract Objective To compare the clinical efficiency and safety between intravitreal injection of conbercept with and without macular photocoagulation for diabetic macular edema (DME). Methods A non-random controlled study was conducted.Sixty patients […]
Comparison of long-term macular morphology after laser retinal photocoagulation and anti-VEGF therapy and their effects on vision prognosis for type 1 ROP
Authors: Guo Lili, Cheng Yong, Deng Xun, Linghu Dandan, Zhu Xuemei, Shi Xuan, Li Xiaoxin, Liang Jianhong DOI: 10.3760/cma.j.cn115989-20210913-00508 Published 2022-01-10 Cite asChin J Exp Ophthalmol, 2022, 40(1): 47-53. Abstract Objective To evaluate and compare the foveal microvascular morphology and central foveal thickness (CFT) after laser retinal photocoagulation and intravitreal injection of anti-vascular endothelial growth […]
Quantification analysis of macular microcirculation in early diabetic patients and its correlation with visual acuity
Authors: Xu Min, Nie Lujuan, Zhang Xue, Chen Fang DOI: 10.3760/cma.j.cn115989-20210419-00263 Published 2022-01-10 Cite asChin J Exp Ophthalmol, 2022, 40(1): 54-61. Abstract Objective To analyze the change of macular microcirculation in early diabetic patients and its correlation with visual acuity. Methods A cross-sectional study was performed.Seventy-five eyes from 75 patients with non-diabetic retinopathy (NDR) and […]
Effects of internal limiting membrane peeling on post-vitrectomy epiretinal membrane and visual prognosis of rhegmatogenous retinal detachment
Authors: Fu Yan, Xie Tianhao, Yang Na, Li Liying, Zhang Yueling, Gu Zhaohui DOI: 10.3760/cma.j.cn115989-20190428-00188 Published 2022-01-10 Cite asChin J Exp Ophthalmol, 2022, 40(1): 62-66. Abstract Objective To analyze the effect of vitrectomy combined with internal limiting membrane (ILM) peeling on the prevention of post-vitrectomy epiretinal membrane (ERM) in macular-off rhegmatogenous retinal detachment (RRD) and […]