Category: Experimental Science

Efficiency and safety of genipin collagen crosslinking on rabbit cornea stroma model in vivo

Authors: Tang Yun,  Song Wenjing,  Qiao Jing,  Rong Bei,  Li Haili,  Yang Songlin,  Yan Xiaoming DOI: 10.3760/cma.j.issn.2095-0160.2019.03.002 Published 2019-03-10 Cite as Chin J Exp Ophthalmol, 2019,37(3): 164-170. Abstract                              [Download PDF] [Read Full Text] Objective To evaluate the efficiency and safety of genipin collagen crosslinking (G-CXL) on rabbit corneas in vivo. Methods Forty […]

Effects of Krüppel-like factor 6 overexpression towards apoptosis of human lens epithelial cells with ultra violetradiation B treatment

Authors: Tian Fang,  Zhao Jinzhi,  Huang Liangyu,  Xu Manhong,  Zhang Zhe,  Teng He,  Zhang Xiaomin,  Li Xiaorong,  Dong Lijie,  Zhang Hong DOI: 10.3760/cma.j.issn.2095-0160.2019.04.004 Published 2019-04-10 Cite as Chin J Exp Ophthalmol, 2019,37(4): 257-262. Abstract                              [View PDF] [Read Full Text] Objective To investigate the effect of the overexpression of Krüppel-like factor 6 (KLF6) towards the apoptosis of […]

The inhibitory effect of decorin on apoptosis of human lens epithelial cells under high glucose condition and its mechanism

Authors: Xie Dandan,  Du Shanshan,  Qi Ying,  Shao Jingzhi,  Zhang Fengyan DOI: 10.3760/cma.j.issn.2095-0160.2019.04.003 Published 2019-04-10 Cite as Chin J Exp Ophthalmol, 2019,37(4): 252-256. Abstract                              [View PDF] [Read Full Text] Objective To investigate the effects of decorin (DCN) on apoptosis and oxidative stress in human lens epithelial cells (LECs) under high […]

Inhibitory effects of glutathione 2 on excessive migration of human lens epithelial cells induced by hyperoxia

Authors: Ning Xiaona,  Yan Hong,  Guo Chenjun,  Liu Fuwei,  Dong Qian DOI: 10.3760/cma.j.issn.2095-0160.2019.04.002 Published 2019-04-10 Cite as Chin J Exp Ophthalmol, 2019,37(4): 245-251. Abstract                              [View PDF] [Read Full Text] Objective To observe the influences of hyperoxia on the migration of human lens epithelial cells (HLECs) and the inhibitory effects of […]

Construction of lentivirus-mediated mito-OGG1 gene overexpression and OGG1 gene knockdown model in 661W cells

Authors: Li Han,  Ma Wei,  Shi Kangpei,  Wang Lei,  Huang Hao,  Wu Wenbin,  Zhang Xiaotong,  Zhu Xiaobo DOI: 10.3760/cma.j.issn.2095-0160.2019.05.006 Published 2019-05-10 Cite as Chin J Exp Ophthalmol, 2019,37(5): 348-356. Abstract                                  [View PDF] [Read Full text] Objective To construct and authenticate the lentiviral-mediated overexpression of mouse […]

Inhibitory effect of Tanshinone ⅡA on the proliferation of human retinal pigment epithelial cells in hypoxia and its mechanism

Authors: Lei Xiang,  Li Zhanrong,  Fan Ke DOI: 10.3760/cma.j.issn.2095-0160.2019.05.005 Published 2019-05-10 Cite as Chin J Exp Ophthalmol, 2019,37(5): 342-347. Abstract                                  [View PDF] [Read Full text] Objective To investigate the effect of Tanshinone ⅡA on the proliferation and the signaling pathway of human retinal pigment epithelial […]

Effect of adenosine kinase small interfering RNA modified corneal endothelial cells on the proliferation and secretion of regulatory T cells

Authors: Zhang Wanhong,  Jiao Huiying,  Ruan Yanfei,  Liu Yuanzhen Published 2019-05-10 DOI: 10.3760/cma.j.issn.2095-0160.2019.05.004 Cite as Chin J Exp Ophthalmol, 2019,37(5): 337-341. Abstract                                  [View PDF] [Read Full text] Objective To investigate the role of adenosine kinase (ADK)small interfering RNA(siRNA) modified corneal endothelial cells on the proliferation […]

Effects of matrine on human Tenon capsule fibroblast in vitro

Authors: Ji Fangfang,  Shuai Jie,  Liang Ya,  Yu Qiuli,  Sun Zhenyan,  Yuan Zhilan DOI: 10.3760/cma.j.issn.2095-0160.2019.05.003 Published 2019-05-10 Cite as Chin J Exp Ophthalmol, 2019,37(5): 332-336. Abstract                                  [View PDF] [Read Full text] Objective To investigate the role of adenosine kinase (ADK)small […]

Inhibitory effect of miR-34a on biological behavior of uveal melanoma cells and its mechanism

Authors: Zhang Ke, Zhu Yu, Wang Lili, Wang Jing DOI: 10.3760/cma.j.issn.2095-0160.2019.05.002 Published 2019-05-10 Cite as Chin J Exp Ophthalmol, 2019,37(5): 326-331. Abstract                                    [View PDF] [Read Full text] Objective To study the effect of microRNA-34a(miR-34a) on the biological behavior […]

Inhibition of hepatocyte growth factor on proliferation and transdifferentiation of human Tenon capsule fibroblasts triggered by transforming growth factor-β1in vitro

Authors: Chen Jing,  Wang Yong,  Li Donghao DOI: 10.3760/cma.j.issn.2095-0160.2018.12.006 Published 2018-12-10 Cite as Chin J Exp Ophthalmol, 2018,36(12): 925-930. Abstract Objective To investigate the effects of hepatocyte growth factor (HGF) on proliferation and transdifferentiation of human Tenon capsule fibroblasts induced by transforming growth factor -β1 (TGF-β1) in vitro. Methods Human Tenon capsule fibroblasts were cultured and divided into […]