Category: Experimental Science

The inhibitory effect of decorin on apoptosis of human lens epithelial cells under high glucose condition and its mechanism

Authors: Xie Dandan,  Du Shanshan,  Qi Ying,  Shao Jingzhi,  Zhang Fengyan DOI: 10.3760/cma.j.issn.2095-0160.2019.04.003 Published 2019-04-10 Cite as Chin J Exp Ophthalmol, 2019,37(4): 252-256. Abstract                              [View PDF] [Read Full Text] Objective To investigate the effects of decorin (DCN) on apoptosis and oxidative stress in human lens epithelial cells (LECs) under high […]

Inhibitory effects of glutathione 2 on excessive migration of human lens epithelial cells induced by hyperoxia

Authors: Ning Xiaona,  Yan Hong,  Guo Chenjun,  Liu Fuwei,  Dong Qian DOI: 10.3760/cma.j.issn.2095-0160.2019.04.002 Published 2019-04-10 Cite as Chin J Exp Ophthalmol, 2019,37(4): 245-251. Abstract                              [View PDF] [Read Full Text] Objective To observe the influences of hyperoxia on the migration of human lens epithelial cells (HLECs) and the inhibitory effects of […]

Construction of lentivirus-mediated mito-OGG1 gene overexpression and OGG1 gene knockdown model in 661W cells

Authors: Li Han,  Ma Wei,  Shi Kangpei,  Wang Lei,  Huang Hao,  Wu Wenbin,  Zhang Xiaotong,  Zhu Xiaobo DOI: 10.3760/cma.j.issn.2095-0160.2019.05.006 Published 2019-05-10 Cite as Chin J Exp Ophthalmol, 2019,37(5): 348-356. Abstract                                  [View PDF] [Read Full text] Objective To construct and authenticate the lentiviral-mediated overexpression of mouse […]

Inhibitory effect of Tanshinone ⅡA on the proliferation of human retinal pigment epithelial cells in hypoxia and its mechanism

Authors: Lei Xiang,  Li Zhanrong,  Fan Ke DOI: 10.3760/cma.j.issn.2095-0160.2019.05.005 Published 2019-05-10 Cite as Chin J Exp Ophthalmol, 2019,37(5): 342-347. Abstract                                  [View PDF] [Read Full text] Objective To investigate the effect of Tanshinone ⅡA on the proliferation and the signaling pathway of human retinal pigment epithelial […]

Effect of adenosine kinase small interfering RNA modified corneal endothelial cells on the proliferation and secretion of regulatory T cells

Authors: Zhang Wanhong,  Jiao Huiying,  Ruan Yanfei,  Liu Yuanzhen Published 2019-05-10 DOI: 10.3760/cma.j.issn.2095-0160.2019.05.004 Cite as Chin J Exp Ophthalmol, 2019,37(5): 337-341. Abstract                                  [View PDF] [Read Full text] Objective To investigate the role of adenosine kinase (ADK)small interfering RNA(siRNA) modified corneal endothelial cells on the proliferation […]