Tag: Pathogenesis

Characteristics of autosomal dominant retinal diseases and gene therapy strategies

Authors: Liu Yanbo, Pang Jijing DOI: 10.3760/cma.j.cn115989-20210329-00215 Published 2021-08-10 Cite asChin J Exp Ophthalmol, 2021, 39(8): 755-760. Abstract                              [View PDF] [Read Full Text] Inherited retinal diseases (IRDs), one type of the major eye diseases resulting in blindness, can be caused by more than 270 identified […]

Progress in pathogenesis and treatment of the elevated intraocular pressure resulted from thyroid associated ophthalmopathy

Authors: Guo Zhenfeng,  Zhao Liang,  Sun Fengyuan DOI: 10.3760/cma.j.cn115989-20191022-00459 Published 2021-07-10 Cite asChin J Exp Ophthalmol, 2021, 39(7): 661-664. Abstract                              [View PDF] [Read Full Text] In adult orbital diseases, thyroid associated ophthalmopathy (TAO) is of very high incidence rate, and it can seriously affect patients’ […]

Research updates on strabismus associated with congenital cataract

Authors: Wu Yazhen,  Yan Hong DOI: 10.3760/cma.j.cn115989-20190401-00159 Published 2021-04-10 Cite asChin J Exp Ophthalmol, 2021, 39(4): 346-350. Abstract                              [View PDF] [Read Full Text] Patients with congenital cataract often present strabismus simultaneously.Strabismus is closely related to the occurrence of cataract, and is one of the main […]

The importance of basic research and drug development for thyroid-associated ophthalmopathy

Author: Fan Xianqun DOI: 10.3760/cma.j.cn115989-20200812-00582 Published 2020-11-10 Cite as Chin J Exp Ophthalmol, 2020,38(11): 905-909. Abstract                               [View PDF] [Read Full Text] Thyroid-associated ophthalmopathy (TAO) is an organ specific autoimmune disease with complex pathogenesis.In recent years, great progress has been made in the pathogenesis of TAO […]

Treatment on retinopathy of prematurity

Authors: Fang Siwen,  Ma Xiang DOI: 10.3760/cma.j.issn.2095-0160.2020.01.016 Published 2020-01-10 Cite as Chin J Exp Ophthalmol, 2020,38(01): 77-80. Abstract                              [View PDF]  [Read Full Text]  Retinopathy of prematurity (ROP) as a leading cause of blindness in children in both developed and developing countries, is […]

Treatment on retinopathy of prematurity

Authors: Fang Siwen,  Ma Xiang DOI: 10.3760/cma.j.issn.2095-0160.2020.01.016 Published 2020-01-10 Cite as Chin J Exp Ophthalmol, 2020,38(01): 77-80. Abstract Retinopathy of prematurity (ROP) as a leading cause of blindness in children in both developed and developing countries, is a type of proliferative retinopathy that occurs in preterm and low birth mass infants.Early treatment can effectively save the […]

Detection and analysis of differential gene expression between benign lymphoepithelial lesion of lacrimal gland and orbital cavernous hemangioma

Authors:Li Jing,  Ge Xin,  Ma Jianmin,  Wang Xiaona,  Liu Xiao DOI: 10.3760/cma.j.issn.2095-0160.2016.10.003 Published 2016-10-10 Cite as Chin J Exp Ophthalmol, 2016,34(10): 878-882. Abstract                            [Download PDF] [Read Full Text] Background Benign lymphoepithelial lesion of lacrimal gland is not a common orbital disease in clinic, which mainly presented as […]

Effects of exosomes in pathogenesis of age-related macular degeneration

Authors: Yang Jing,  Chen Song DOI: 10.3760/cma.j.issn.2095-0160.2017.01.018 Published 2017-01-10 Cite as Chin J Exp Ophthalmol, 2017,35(1): 83-86. Abstract                              [Download PDF] [Read Full Text] Exosomes are nanometer membranous vesicles which can be distributed in a variety of biological fluids, including peripheral blood, urine, saliva and so on.Currently, the […]

The role of integrin-linked kinase in the pathogenesis of cataract

Authors: Yu Jingjing,  Zheng Zhi DOI: 10.3760/cma.j.issn.2095-0160.2017.03.021 Published 2017-03-10 Cite as Chin J Exp Ophthalmol, 2017,35(3): 282-285. Abstract                               [Download PDF] [Read Full Text] Integrin is a cell surface receptor that is widely expressed in mammals.Integrin-linked kinase (ILK) is a key kinase of the integrin signaling pathway which […]

Paying attention to the concept and research of pachychoroid disease spectrum

Authors: Zhang Xinyuan,  Timothy Y.Y.Lai. DOI: 10.3760/cma.j.issn.2095-0160.2017.05.001 Published 2017-05-10 Cite as Chin J Exp Ophthalmol, 2017,35(5): 385-390. Abstract                              [Download PDF] [Read Full Text] Pachychoroid disease spectrum is a novel concept in ophthalmology upon the development of ocular diagnosis and treatment.Recent breakthroughs and advancements in OCT imaging technology […]