Tag: Proliferation

Inhibitory effects of α-crystallin on optic nerve astrocytes proliferation, activation and secretion stimulated by lipopolysaccharide

Authors:Liu Xiao,  Shao Weiyang,  Gu Xianliang,  Wang Yi DOI: 10.3760/cma.j.issn.2095-0160.2016.12.007 Published 2016-12-10 Cite as Chin J Exp Ophthalmol, 2016,34(12): 1082-1086. Abstract                              [Download PDF] [Read Full Text] Background Glial scaring induced by the activation and proliferation of astrocytes after optical nerve damage is one of causes of neural axons difficult to regeneration.Researches […]

The proliferative inhibition and apoptosis promotion of Smac on human lens epithelial cells

Authors: Kong Deqian,  Zheng Guangying,  Li Li,  Liu Yue,  Cai Fangfei DOI: 10.3760/cma.j.issn.2095-0160.2017.03.010 Published 2017-03-10 Cite as Chin J Exp Ophthalmol, 2017,35(3): 233-238. Abstract                            [Download PDF] [Read Full Text] Background Posterior capsular opacification (PCO) is a primary complication after extracapsular cataract extraction.The mechanism of PCO is associated with proliferation, migration and […]

The inhibitory effects of baicalein on overexpression of proline hydroxylase 2 in hypoxia-induced retinal glial cells

Authors: Yang Ning,  Lu Qiang,  Yuan Mengke,  Zhang Han,  Cui Wei DOI: 10.3760/cma.j.issn.2095-0160.2017.11.007 Published 2017-11-10 Cite as Chin J Exp Ophthalmol, 2017,35(11): 990-996. Abstract                              [Download PDF] [Read Full Text] Background Proline hydroxylase 2 (PHD2) is a degrading enzyme of hypoxia-inducible factor-1α (HIF-1α) and can regulate the expression of vascular endothelial […]

Comparision of the pharmacodynamics between different batches of recombinant decoy receptor innovative drug RC28-E in retinal vascular endothelial cells

Authors: Zheng Jialin,  Yang Qianhui,  Sun Jing,  Zhang Hong,  Jiang Jing,  Huang Min,  Li Shenjun,  Fang Jianmin,  Li Xiaorong,  Zhang Yan DOI: 10.3760/cma.j.issn.2095-0160.2018.12.003 Published 2018-12-10 Cite as Chin J Exp Ophthalmol, 2018,36(12): 908-913. Abstract                               [Download PDF] [Read Full Text] Objective To compare the protective effects of pharmacological batch RC28-E1 and pilot batch RC28-E2 on retinal […]

Inhibitory effect of Tanshinone ⅡA on the proliferation of human retinal pigment epithelial cells in hypoxia and its mechanism

Authors: Lei Xiang,  Li Zhanrong,  Fan Ke DOI: 10.3760/cma.j.issn.2095-0160.2019.05.005 Published 2019-05-10 Cite as Chin J Exp Ophthalmol, 2019,37(5): 342-347. Abstract                                  [View PDF] [Read Full text] Objective To investigate the effect of Tanshinone ⅡA on the proliferation and the signaling pathway of human retinal pigment epithelial […]