Authors: Chen Chong, Xu Xun DOI: 10.3760/cma.j.issn.2095-0160.2015.12.017 Published 2015-12-10 Cite as Chin J Exp Ophthalmol, 2015,33(12): 1131-1137. Abstract [Download PDF] [Read Full Text] Drug deliver to the posterior eye segment (retinal tissue and vitreous) via systemic administration is constrained due to the presence […]
Tag: Retinal pigment epithelium
Inhibitory effects of N-acetylcysteine and salubrinal on apoptosis of retinal pigment epithelial cells induced by all-trans-retinoic acid
Authors: Wu Juan, Cui Dongmei, Zeng Junwen DOI: 10.3760/cma.j.cn115989-20200414-00262 Published 2023-01-10 Cite as Chin J Exp Ophthalmol, 2023, 41(1): 16-21. Abstract [Download PDF] [Read Full Text] Objective To observe the effect of the antioxidant N-acetylcysteine (NAC) and selective endoplasmic […]
New insights into the integrity of intercellular junctions between retinal pigment epithelial cells
Authors: Wei Jiayi, Wang Fang DOI: 10.3760/cma.j.cn115989-20201212-00839 Published 2022-07-10 Cite asChin J Exp Ophthalmol, 2022, 40(7): 670-674. Abstract [View PDF] [Read Full Text] Retinal pigment epithelium (RPE) is composed of a layer of highly specialized hexagonal pigment epithelial cells.The apical surface of […]
Effect of ROS/NLRP3/Caspase-1 signaling pathway on the apoptosis of retinal pigment epithelial cells induced by high glucose
Authors: Li Hongsong, Li Rong, Wang Lijun, Liao Dingying, Wang Jianming DOI: 10.3760/cma.j.cn115989-20210420-00267-1 Published 2022-01-10 Cite asChin J Exp Ophthalmol, 2022, 40(1): 6-12. Abstract [View PDF] [Read Full Text] Objective To investigate the effect of the nucleotide-binding domain, leucine-rich-containing family, pyrin […]
Inhibitory effects of NADPH oxidase 4 inhibitor on VEGF expression in hypoxia-induced human RPE cells
Authors: Li Jing, Yang Jing, Kang Qianyan DOI: 10.3760/cma.j.issn.2095-0160.2020.01.002 Published 2020-01-10 Cite as Chin J Exp Ophthalmol, 2020,38(01): 4-9. Abstract [View PDF] [Read Full Text] Objective To observe the inhibitory effects of nicotinamide adenine dinucleotide phosphate oxidase 4 (NOX4) on vascular endothelial […]
Focus on stem cell-based therapy for retinal degenerative diseases
Author: Liu Qinghuai DOI: 10.3760/cma.j.issn.2095-0160.2019.11.001 Published 2019-11-10 Cite as Chin J Exp Ophthalmol, 2019,37(11): 849-853. Abstract [View PDF] [Read Full Text] Retinal degenerative diseases are the common cause of blindness for all ages.Cell replacement therapy is the main strategy for treating retinal […]
Appilcation of polycaprolactone/collagen nanofibrous membranes in constituting tissue engineering retinal pigment epithelium
Authors: Tang Tian, Chen Jie, Deng Hua, Yin Xiaoguang, Fu Yan DOI: 10.3760/cma.j.issn.2095-0160.2019.11.007 Published 2019-11-10 Cite as Chin J Exp Ophthalmol, 2019,37(11): 884-887. Abstract [View PDF] [Read Full Text] Objective To explore the potential of polycaprolactone (PCL)/gelatin nanofibrous composite membrane in constituting tissue engineering retinal pigment […]
Rapid differentiation of human ESCs into RPE cells by defined xeno-free culture system
Authors: Liu Qiuhui, Wang Jing, Tian Rong, Wang Xiao, Cao Di, Lu Jing, Luo Yan DOI: 10.3760/cma.j.issn.2095-0160.2016.06.002 Published 2016-06-10 Cite as Chin J Exp Ophthalmol, 2016,34(6): 484-488. Abstract [Download PDF] [Read Full Text] Background Subretinal transplantation of retinal pigment epithelium (RPE) cells for the treatment of age-related […]
Inhibitory effect of curcumin, salvia miltiorrhiza and matrine on IL-1β-induced proliferation of rabbit RPE cells in vitro
Authors: Liu Liya, Ma Jingxue, An Jianbin, Liu Danyan, Gao Yanjun, Zhou Nalei, Ma Yuelei DOI: 10.3760/cma.j.issn.2095-0160.2016.08.006 Published 2016-08-10 Cite as Chin J Exp Ophthalmol, 2016,34(8): 699-704. Abstract [Download PDF] [Read Full Text] Background Proliferative vitreoretinopathy (PVR) is a common cause of vision loss clinically, and retinal […]
Research progress on correlation between microRNA and retinal development
Authors: Liu Xiaochen, Wu Min DOI: 10.3760/cma.j.issn.2095-0160.2017.08.021 Published 2017-08-10 Cite as Chin J Exp Ophthalmol, 2017,35(8): 764-768. Abstract [Download PDF] [Read Full Text] MicroRNAs (miRNAs) are small, stable RNA molecules that post-transcriptionally regulate gene expression in plants and animals by base pairing to partially complementary sequences on […]