Category: Experimental Science

Protective effect of COG1410 on the survival of retinal ganglion cells in mice with retinal ischemia-reperfusion injury and its mechanism

Authors: Zhao Ru,  Luo Jinyuan,  He Tao,  Xing Yiqiao DOI: 10.3760/cma.j.cn115989-20221116-00534 Published 2023-11-10 Cite as Chin J Exp Ophthalmol, 2023, 41(11): 1065-1075. Abstract                            【Download PDF】 【Read Full Text】 Objective To explore the effects of apolipoprotein E-mimetic peptide COG1410 on M1/M2 microglia polarization and […]

Dedifferentiation and regulation mechanism of TNF-α on orbital fibroblasts in thyroid-associated ophthalmopathy

Authors: Jing Yapeng,  Huang Xiaoming,  Wu Tong,  Jian Tianming,  Shi Shuangshuang,  Zhao Liang,  Sun Fengyuan,  Tang Dongrun DOI: 10.3760/cma.j.cn115989-20210119-00051 Published 2023-11-10 Cite as Chin J Exp Ophthalmol, 2023, 41(11): 1076-1083. Abstract                            【Download PDF】 【Read Full Text】 Objective To investigate the effect of tumor […]

Investigation of the tissue-damaging effects and mechanisms of neutrophil-derived MMP-8 in Fusarium keratitis

Authors: Dong Junlu,  Jin Xin,  Liu Hua,  Jian Shoujun,  Yue Juan,  Zhang Hongmin,  Wang Liya DOI: 10.3760/cma.j.cn115989-20210714-00412 Published 2023-10-10 Cite as Chin J Exp Ophthalmol, 2023, 41(10): 961-969. Abstract                              【Download PDF】 【Read Full Text】 Objective To investigate the mechanism of tissue damage […]

Inhibitory effect of miR-27b-3p and Nrf2 regulation on metabolic memory formation in human RPE cells

Authors: Lai Qiaoling,  Xie Ting,  Huang Yan DOI: 10.3760/cma.j.cn115989-20201208-00831 Published 2023-10-10 Cite as Chin J Exp Ophthalmol, 2023, 41(10): 970-979. Abstract                              【Download PDF】 【Read Full Text】 Objective To investigate the effect of microRNA-27b-3p (miR-27b-3p)/nuclear factor-E2-related factor 2 (Nrf2) on metabolic memory impairment […]

Inhibitory effect of GALNT2 gene knockdown on apoptosis of human retinal vascular endothelial cells in high glucose culture and its mechanism

Authors: Sun Tianyang,  Geriletu,  Zhang Yufeng,  Li Chunyu,  Jin Lin,  Bao Lingjun,  Wang Jiale DOI: 10.3760/cma.j.cn115989-20221207-00576 Published 2023-09-10 Cite as Chin J Exp Ophthalmol, 2023, 41(9): 846-853. Abstract                            【Download PDF】 【Read Full Text】 Objective To investigate the effect of polypeptide N-acetylgalactosaminaminyltransferase 2 (GALNT2) […]

Inhibitory effect of miR-497 on the repair of diabetic mice corneal epithelial damage by targeting wnt3a

Authors: Huang Yuqing,  Yang Yanning,  Wang Yang,  Pan Yumiao,  Cheng Simin DOI: 10.3760/cma.j.cn115989-20220108-00005 Published 2023-09-10 Cite as Chin J Exp Ophthalmol, 2023, 41(9): 856-863. Abstract                           【Download PDF】 【Read Full Text】 Objective To investigate the inhibitory effect of miR-497 on the corneal epithelial healing in […]

Digital measurement of corneal curvature and eccentricity of guinea pigs using Python

Authors: Di Yue,  Li Xinyue,  Fang Wangyi,  Huang Ying,  Luo Wenting,  Ye Haiyun,  Qiao Zhongbao,  Qiao Tong DOI: 10.3760/cma.j.cn115989-20220727-00349 Published 2023-08-10 Cite as Chin J Exp Ophthalmol, 2023, 41(8): 724-729. Abstract                               [Download PDF] [Read Full Text] Objective To investigate an accurate and […]

Inhibitory effect of blue light intervention on lens-induced myopia development in guinea pigs and the mechanism of cone density change

Authors: Zou Leilei,  Liu Rui,  Liu Hong,  Dai Jinhui DOI: 10.3760/cma.j.cn115989-20221018-00484 Published 2023-08-10 Cite as Chin J Exp Ophthalmol, 2023, 41(8): 730-738. Abstract                               [Download PDF] [Read Full Text] Objective To observe the effects of blue light intervention on the development of optical […]

Retinal photoreceptor cell damage caused by diabetes through down-regulation of glutathione peroxidase 4 and its mechanism

Authors: Xiao Ke,  Yu Huimin,  Sun Xufang,  Chen Xuhui DOI: 10.3760/cma.j.cn115989-20220928-00459 Published 2023-08-10 Cite as Chin J Exp Ophthalmol, 2023, 41(8): 739-745. Abstract                               [Download PDF] [Read Full Text] Objective To investigate the changes of glutathione peroxidase 4 (GPX4) in retinal photoreceptor cells, […]

Relationship between regression of the hyaloid vessels and development of retinal vessels in mice

Authors: Qin Jiahui,  Guo Yatu,  Zhang Wei DOI: 10.3760/cma.j.cn115989-20210409-00241 Published 2023-07-10 Cite as Chin J Exp Ophthalmol, 2023, 41(7): 623-629. Abstract                              [Download PDF] [Read Full Text] Objective To explore the process of regression of the hyaloid vessels and development of retinal vessels […]