Authors: Qi Yun, Bai Yujing, Li Xiaoxin, Shi Xuan DOI: 10.3760/cma.j.issn.2095-0160.2016.01.004 Published 2016-01-10 Cite as Chin J Exp Ophthalmol, 2016,34(1): 17-23. Abstract [Download PDF] [Read Full Text] Background Choroidal neovascularization (CNV) is the primary pathogenic cause of many fundus diseases.Oxidative stress injury of retinal pigment epithelial (RPE) cells plays important […]
Tag: Choroidal neovascularization
The sustained releasing ability of CEL-PLGA-MS in vitro and its inhibitory effects on experimental choroidal neovascularization after intravitreal injection
Authors: Chen Pengfei, Hao Yuhua, Yang Na, An Jianbin, Liu Liya, Ma Jingxue DOI: 10.3760/cma.j.issn.2095-0160.2016.06.003 Published 2016-06-10 Cite as Chin J Exp Ophthalmol, 2016,34(6): 489-495. Abstract [Download PDF] [Read Full Text] Background Choroidal neovascularization (CNV) is a common pathological basis of many ocular fundus diseases.Some treating methods […]
Clinical safety and efficacy of conbercept intravitreal injection on high myopic choroidal neovascularization
Authors: Jiao Mingfei, Li Xiaorong DOI: 10.3760/cma.j.issn.2095-0160.2016.08.013 Published 2016-08-10 Cite as Chin J Exp Ophthalmol, 2016,34(8): 725-728. Abstract [Download PDF] [Read Full Text] Background choroidal neovascularization (CNV) is the common reason of visual acuity impairment in high myopia patients, which usually leads to irreversible central visual impairment. […]
Aspirin and the formation of eye neovascularization
Authors: Jiang Mengnan, Shen Yin, Xing Yiqiao DOI: 10.3760/cma.j.issn.2095-0160.2017.02.019 Published 2017-02-10 Cite as Chin J Exp Ophthalmol, 2017,35(2): 184-188. Abstract [Download PDF] [Read Full Text] Aspirin is one of the most important non-steroidal anti-inflammatory drugs, could inhibit cyclooxygenase.It has the antipyretic-analgesic, anti-inflammatory and anti-platelet effects, and has been […]
Expression of CD147 in laser-induced rat choroidal neovascularization model
Authors: Wang Wenqiu, Lu Fengqing, Wang Hong, Sun Xiaodong DOI: 10.3760/cma.j.issn.2095-0160.2017.10.007 Published 2017-10-10 Cite as Chin J Exp Ophthalmol, 2017,35(10): 890-893. Abstract [Download PDF] [Read Full Text] Background The pathology of choroidal neovascularization (CNV) is not clear.CD147 plays a critical role in angiogenesis through activating […]
Research progress of long noncoding RNAs in ocular proliferative diseases
Authors: Huang Xiaobo, Zou Haidong DOI: 10.3760/cma.j.issn.2095-0160.2017.12.017 Published 2017-12-10 Cite as Chin J Exp Ophthalmol, 2017,35(12): 1135-1138. Abstract [Download PDF] [Read Full Text] Ocular proliferative diseases, such as proliferative vitreous retinopathy (PVR), diabetic retinopathy (DR), choroidal neovascularization, corneal neovascularization and so on, […]
The promoting effects of SNAI1 activating matrix metalloproteinase on choroidal neovascularization under hypoxia
Authors: Sun Jiaxing, Dou Guorui, Chang Tianfang, Li Manhong, Yang Ziyan, Yan Xianchun, Liu Yuan, Han Hua, Wang Yusheng DOI: 10.3760/cma.j.issn.2095-0160.2018.01.004 Published 2018-01-10 Cite as Chin J Exp Ophthalmol, 2018,36(1): 16-22. Abstract [Download PDF] [Read Full Text] Objective To investigate whether vascular endothelial cells in choroidal neovascularization whether hypoxia condition can up-regulate SNAI1 and […]
Analysis of long-term outcomes and causes influencing visual prognosis in eyes receiving anti-VEGF-A for wet age-related macular degeneration
Authors: Yang Shiqi, Sun Xiaodong DOI: 10.3760/cma.j.issn.2095-0160.2018.03.016 Published 2018-03-10 Cite as Chin J Exp Ophthalmol, 2018,36(3): 236-240. Abstract [Download PDF] [Read Full Text] As a progressive chronic disease, age-related macular degeneration (AMD) is the leading cause of blindness worldwide.However, current therapy for AMD shows a dramatic breakthrough.More […]
Effect of Eylea on recombinant AAV2-VEGF-induced choroidal neovascularization
Authors: Jiang Laisheng, Liao Qin, Cai Keyang, Sun Huiye, Sun Yunxia DOI: 10.3760/cma.j.issn.2095-0160.2018.08.008 Published 2018-08-10 Cite as Chin J Exp Ophthalmol, 2018,36(8): 608-612. Abstract [Download PDF] [Read Full Text] Objective To evaluate the effect of Eylea (aflibercept) on recombinant adeno-associated virus 2(AAV2)-vascular endothelial growth factor (VEGF)-induced choroidal neovascularization (CNV). Methods […]
The suppression mechanisms of quercetin in retinal and choroidal neovascularization through integrin signal pathway
Authors: Yue Yankun, Wang Haiwei, Deng Yu, Tian Mo, Wang Yinlin, Zhang Enkui DOI: 10.3760/cma.j.issn.2095-0160.2018.08.007 Published 2018-08-10 Cite as Chin J Exp Ophthalmol, 2018,36(8): 602-607. Abstract [Download PDF] [Read Full Text] Objective To investigate the mechanisms of quercetin in retinal angiogenesis via in vitro and in vivo studies. Methods Human umbilical […]