Authors: Ding Jie, Xin Xiangyang, Zhao Xin DOI: 10.3760/cma.j.cn115989-20241207-00337 Published: 2025 -07 -10 Citation Ding Jie, Xin Xiangyang, Zhao Xin. Inhibitory effect of asparagine synthetase knockdown on retinal pigment epithelial cell senescence and its underlying mechanism[J]. Chin J Exp Ophthalmol, 2025, 43(7):592-602. DOI: 10.3760/cma.j.cn115989-20241207-00337. ABSTRACT [Download PDF] [View Full Text] Objective […]
Tag: Macular degeneration
The current study, challenges and application of stem cell transplantation in ophthalmology
Authors: Yin Zhengqin, Li Shiying, Jian Qian DOI: 10.3760/cma.j.issn.2095-0160.2015.09.001 Published 2015-09-10 Cite as Chin J Exp Ophthalmol, 2015,33(9): 769-773. Abstract [Download PDF] [Read Full Text] Stem cells are a group of undifferentiated cells with indefinite self-renewal and pluripotent differentiation ability. They are able […]
Research progress in autophagy on dry age-related macular degeneration
Authors: Yan Quan, Sun Xiaodong DOI: 10.3760/cma.j.issn.2095-0160.2015.10.018 Published 2015-10-10 Cite as Chin J Exp Ophthalmol, 2015,33(10): 949-952. Abstract [Download PDF] [Read Full Text] Age-related macular degeneration (AMD) is a common cause of vision loss and living quality impairment in elderly people.Dry AMD […]
Molecular mechanism of lutein protecting Müller cells against oxidative stress induced by H2O2
Authors: Yang Xu, Wang Mingchen, Sun Yanyan, An Huijuan, Li Qingfu, Bao Yuzhou DOI: 10.3760/cma.j.issn.2095-0160.2015.11.010 Published 2015-11-10 Cite as Chin J Exp Ophthalmol, 2015,33(11): 1009-1014. Abstract [Download PDF] [Read Full Text] Background Oxidative stress is a main cause of age-related macular degeneration (AMD). […]
Inhibitory effect of ranibizumab on retinal oxidative stress in a rat model of choroidal neovascularization and its mechanism
Authors: Yang Yanzhen, Zhuang Xianli, Li Shujie, Zhang Ying, Yang Jiagan, Li Lulu DOI: 10.3760/cma.j.cn115989-20210930-00543 Published 2023-01-10 Cite as Chin J Exp Ophthalmol, 2023, 41(1): 22-28. Abstract [Download PDF] [Read Full Text] Objective To study the effect of ranibizumab […]
Inhibitory effect of ZhuJing pill variant formula medicated serum on H2O2-induced epithelial-mesenchymal transition of human RPE cells and its mechanism
Authors: Shao Yan, Zhang Yuanzhong, Yang Ning, Hang Li, Chen Chunming, Li Min, Xu Xinrong DOI: 10.3760/cma.j.cn115989-20210907-00501 Published 2022-11-10 Cite asChin J Exp Ophthalmol, 2022, 40(11): 1013-1022. Abstract [View PDF] [Read Full Text] Objective To study the effect of ZhuJing pill variant […]
Critical guiding role of OCT angiography in long-term treatment and follow-up of neovascular AMD
Authors: Bo Qiyu, Sun Xiaodong DOI: 10.3760/cma.j.cn115989-20220617-00282 Published 2022-07-10 Cite asChin J Exp Ophthalmol, 2022, 40(7): 604-608. Abstract [View PDF] [Read Full Text] The pathogenesis of neovascular age-related macular degeneration (nAMD) is complex and macular neovascularization (MNV), a key pathogenic factor in […]
NLRP3 inflammasome and its role in age-related macular degeneration
Authors: Chen Lu, Xie Ping, Hu Zizhong DOI: 10.3760/cma.j.cn115989-20210922-00527 Published 2022-01-10 Cite as Chin J Exp Ophthalmol, 2022, 40(1): 73-77. Abstract [View PDF] [Read Full Text] Age-related macular degeneration (AMD), the leading cause of central vision loss among people aged 50 years […]
Research progress of purinergic signaling in dry age-related macular degeneration
Authors: Hu Yifan, Sun Xiaodong DOI: 10.3760/cma.j.cn115989-20190717-00316 Published 2022-01-10 Cite asChin J Exp Ophthalmol, 2022, 40(1): 78-82. Abstract [View PDF] [Read Full Text] Age-related macular degeneration (AMD) is one of the major causes of visual loss in people over 65 years […]
Role of retinal microglia-mediated parainflammation in age-related macular degeneration
Authors: Wang Yuwei, Li Jing DOI: 10.3760/cma.j.cn115989-20210922-00526 Published 2021-11-10 Cite asChin J Exp Ophthalmol, 2021, 39(11): 1021-1024. Abstract [View PDF] [Read Full Text] Age-related macular degeneration (AMD) is a disease caused by multiple factors such as age, genetics and environmental risks.Inflammation plays an important role […]