Tag: Retinal ganglion cells

Protective effect of NLRP12 knockdown on retinal damage in rats with ocular hypertension and its mechanism of inhibiting cell pyroptosis

Authors: Song Weiqiong,  He Fang,  Du Lingfang,  Tan Huaxia,  Liu Dan DOI: 10.3760/cma.j.cn115989-20211021-00572 Published 2023-02-10 Cite as Chin J Exp Ophthalmol, 2023, 41(2): 110-118. Abstract                              [Download PDF] [Read Full Text] Objective To investigate the effect and mechanism of NOD-like receptor family pyrin […]

Regulation of the non-image-forming visual circuit on physiological activity and behavior

Authors: Yuan Man,  Shen Yin DOI: 10.3760/cma.j.cn115989-20201222-00859 Published 2023-02-10 Cite as Chin J Exp Ophthalmol, 2023, 41(2): 192-195. Abstract                              [Download PDF] [Read Full Text] Retinal ganglion cells (RGCs) are final output neurons from the retina to the brain, which can transmit light […]

Pressure-induced differentiation of rabbit retinal stem cells into retinal ganglion cells

Authors: Dai Min,  Kang Zefeng,  Hu Zhulin,  Li Yan DOI: 10.3760/cma.j.cn115989-20200519-00361 Published 2022-12-10 Cite as Chin J Exp Ophthalmol, 2022, 40(12): 1134-1140. Abstract                              [View PDF] [Read Full Text] Objective To investigate the effect of pressure on the differentiation of rabbit retinal stem […]

Research progress on protective strategies for optic nerve injury

Authors: Yu Jinhai,  Liao Hongfei,  Wang Yaohua DOI: 10.3760/cma.j.cn115989-20191226-00559 Published 2022-11-10 Cite asChin J Exp Ophthalmol, 2022, 40(11): 1090-1094. Abstract                              [View PDF] [Read Full Text] Traumatic optic neuropathy and glaucoma can cause optic nerve degenerative changes leading to a significant decline […]

New paradigms of immune regulation in glaucoma during the whole clinical process

Authors: Wu Jian,  Su Wenru,  Zhuo Yehong DOI: 10.3760/cma.j.cn115989-20220314-00104 Published 2022-04-10 Cite asChin J Exp Ophthalmol, 2022, 40(4): 289-293. Abstract                              [View PDF] [Read Full Text] Glaucoma is an irreversible blinding eye disease caused by the structural and functional damage of optic nerve induced by pathological […]

Inhibitory effect of necrostatin-1 on necroptosis of retinal ganglion cells in rats with acute ocular hypertension

Authors: Jing Yuanyuan,  Ma Yi,  Wang Kai,  Liu Zhuqing DOI: 10.3760/cma.j.cn115989-20191108-00488 Published 2022-04-10 Cite asChin J Exp Ophthalmol, 2022, 40(4): 310-315. Abstract                              [View PDF] [Read Full Text] Objective To investigate the inhibitory effect of specific inhibitor of necroptosis necrostatin-1 (Nec-1) on […]

Effect of human umbilical cord derived mesenchymal stem cells on apoptosis of rat retinal ganglion cells under high glucose and on the regulation of p38MAPK pathway

Authors: Liu Xi,  Sun Xiaoping,  Yang Jianwei,  Zhu Dongmei,  Wang Yuan DOI: 10.3760/cma.j.cn115989-20200804-00559 Published 2022-01-10 Cite asChin J Exp Ophthalmol, 2022, 40(1): 21-28. Abstract                              [View PDF] [Read Full Text] Objective To investigate the effect of human umbilical cord mesenchymal stem cells (hUC-MSC) […]

Research progress of autophagy in the pathogenesis of glaucoma

Authors: Xu Yaohan,  Han Wei DOI: 10.3760/cma.j.cn115989-20210712-00407 Published 2021-10-10 Cite asChin J Exp Ophthalmol, 2021, 39(10): 923-928. Abstract                               [View PDF] [Read Full Text] Glaucoma, a neurodegenerative disease characterized by progressive death of retinal ganglion cells (RGCs) and chronic axonal degeneration, is often associated with elevated […]

Repair effect of platelet-rich plasma on traumatic optic nerve injury in rabbits and its mechanism

Authors: Li Linling,  Xing Yiqiao DOI: 10.3760/cma.j.cn115989-20200701-00468 Published 2021-03-10 Cite as Chin J Exp Ophthalmol, 2021, 39(3): 198-206. Abstract                               [View PDF] [Read Full Text] Objective To study the therapeutic effect and mechanism of autologous platelet-rich plasma (PRP) on rabbit traumatic optic neuropathies (TON) and retina. […]

Inhibitory effects of resveratrol on high glucose-induced apoptosis of retinal cells

Authors: Li Qingchun,  Li Dai,  Xing Yiqiao DOI: 10.3760/cma.j.cn115989-20200519-00351 Published 2020-11-10 Cite as Chin J Exp Ophthalmol, 2020,38(11): 929-935. Abstract                               [View PDF] [Read Full Text] Objective To investigate the inhibitory effects of resveratrol (Res) on the apoptosis of retinal neurons of diabetic rats and ARPE-19 […]