Authors: Liang Yuping, Chen Weiqi, Hong Yu, Gao Xiuyun, Guo Maosheng DOI: 10.3760/cma.j.cn115989-20201108-00754 Published 2021-08-10 Cite asChin J Exp Ophthalmol, 2021, 39(8): 693-699. Abstract [View PDF] [Read Full Text] Objective To investigate the protective effect of adeno-associated virus (AAV) vector-mediated heme oxygenase-1 (HO-1) gene overexpression […]
Tag: Retinitis pigmentosa
Genotypic and phenotypic analysis of RHO gene variants in a Chinese Han autosomal dominant retinitis pigmentosa family
Authors: Zhang Yuwei, Lou Guiyu, Yang Ke, Yang Lin, Zhu Qing, Lei Bo DOI: 10.3760/cma.j.cn115989-20201217-00848 Published 2021-08-10 Cite asChin J Exp Ophthalmol, 2021, 39(8): 708-713. Abstract [View PDF] [Read Full Text] Objective To analyze the pathogenic genes and clinical phenotypes of a Chinese Han family […]
Identification of novel compound heterozygous mutations of USH2A gene in a RP pedigree by targeted-capture next generation sequencing
Authors: Wang Ying, Huang Hui, Fan Ning, Wu Jing, Zhou Xiaomin, Yin Yan, Wang Yun, Liu Xuyang DOI: 10.3760/cma.j.issn.2095-0160.2016.03.011 Published 2016-03-10 Cite as Chin J Exp Ophthalmol, 2016,34(3): 244-247. Abstract [Download PDF] [Read Full Text] Background RP is the term given to a set of hereditary retinal diseases.RP has […]
Gene mutation spectrum analysis of retinitis pigmentosa patients in Ningxia Region of China
Authors:Rong Weining, Qi Rui, Wang Xiaoguang, Fang Xinhe, Sheng Xunlun DOI: 10.3760/cma.j.issn.2095-0160.2019.09.013 Published 2019-09-10 Cite as Chin J Exp Ophthalmol, 2019,37(9): 750-754. Abstract [View PDF] [Read Full Text] Objective To analysis the gene mutation spectrum of retinitis pigmentosa (RP) patients in Ningxia Region of China. Methods […]
Progress in developing a sodium iodate-induced retinitis pigmentosa animal model
Authors: Fan Meihua, Chen Yongxiong DOI: 10.3760/cma.j.issn.2095-0160.2016.09.018 Published 2016-09-10 Cite as Chin J Exp Ophthalmol, 2016,34(9): 860-864. Abstract [Download PDF] [Read Full Text] Retinitis pigmentosa (RP) is a group of clinically and genetically heterogeneous retinal degenerative hereditary diseases that cause severe vision impairment […]
Dynamic changes of FasL protein expression in retinal tissue with aging in retinal degeneration mice
Authors: Tian J, Li Genlin DOI: 10.3760/cma.j.issn.2095-0160.2017.01.004 Published 2017-01-10 Cite as Chin J Exp Ophthalmol, 2017,35(1): 17-21. Abstract [Download PDF] [Read Full Text] Background Retinal transplantation is a new approach to the treatment of retinal degeneration diseases, and how to avoid or reduce the immune rejection after […]
Current advances on the brain-derived neurotrophic factor in therapy of retinitis pigmentosa
Authors: Yan Bojing, Li Genlin DOI: 10.3760/cma.j.issn.2095-0160.2017.03.017 Published 2017-03-10 Cite as Chin J Exp Ophthalmol, 2017,35(3): 267-271. Abstract [Download PDF] [Read Full Text] Brain-derived neurotrophic factor (BDNF) is a kind of small molecule basic protein mainly synthesized in cortical areas and widely expressed in central nervous system.According […]
Update on mutations of precursor mRNA splicing factor genes linked to retinitis pigmentosa
Authors: Xia Weiyi, Zhao Chen DOI: 10.3760/cma.j.issn.2095-0160.2017.08.018 Published 2017-08-10 Cite as Chin J Exp Ophthalmol, 2017,35(8): 752-755. Abstract [Download PDF] [Read Full Text] Retinitis pigmentosa (RP), one of the common forms of hereditary retinal dystrophies (HRD), is typified by significant genetic heterogeneities.Executed by the spliceosome, precursor mRNA […]
Advances in basic researches of pharmacological approachs of retinitis pigmentosa
Authors: Gao Qing, Shen Yin DOI: 10.3760/cma.j.issn.2095-0160.2018.01.015 Published 2018-01-10 Cite as Chin J Exp Ophthalmol, 2018,36(1): 70-74. Abstract [Download PDF] [Read Full Text] Retinitis pigmentosa (RP) is a hereditary ocular disease that can cause blindness.There is no effective treatment currently.Although new technologies, such as gene therapy, stem […]
Research progress of stem cells in the treatment of retinal degenerative diseases
Authors: Zhang Kefan, Qu Xiuxia, Fan Guoping DOI: 10.3760/cma.j.issn.2095-0160.2018.11.011 Published 2018-11-10 Cite as Chin J Exp Ophthalmol, 2018,36(11): 871-877. Abstract [Download PDF] [Read Full Text] Eyes are important human organs, and retinal degenerative diseases can cause irreversible blindness.Up to date, cell transplantation is an important method for the […]