Category: Experimental Science

Ocular safety of intravitreal injection of a novel nanoparticle ciliary neurotrophic factor complex in cynomolgus macaques——a morphological evaluation

Authors: Zhang Tianlu,  Liu Yifan,  Shen Yin DOI: 10.3760/cma.j.cn115989-20220212-00052 Published 2024-07-10 Cite as Chin J Exp Ophthalmol, 2024, 42(7): 613-620. Abstract                             【Download PDF】【Read Full Text】 Objective To evaluate the safety of a novel nanoparticle neurotrophic factor complex for intraocular application in non-human primates. […]

Comparison of the pharmacokinetics of gatifloxacin ophthalmic gel in rabbit ocular tissues with different dosing frequencies

Authors: Wang Xiaotong,  Zhao Xin,  Zu Wei,  Shen Xu,  Chen Shichao,  Yang Qiang DOI: 10.3760/cma.j.cn115989-20220513-00215 Published 2024-07-10 Cite as Chin J Exp Ophthalmol, 2024, 42(7): 621-628. Abstract                            【Download PDF】【Read Full Text】 Objective To establish a method for determining the concentration of gatifloxacin in […]

Efficacy and safety of HA-Mg drainage plate implantation in anterior chamber for intraocular pressure control in rabbit eyes

Authors: Zhu Xiaomin,  Luo Wangdu,  Lin Yi,  Cai Mingming,  Chen Yi,  Xie Lin,  Wang Yong,  Li Xiangji DOI: 10.3760/cma.j.cn115989-20230301-00071 Published 2024-06-10 Cite as Chin J Exp Ophthalmol, 2024, 42(6): 503-510. Abstract                               [Download PDF] [Read Full Text] Objective To evaluate the safety and […]

Proteomic analysis of aqueous humor in patients with exfoliation syndrome

Authors: Xu Zhao,  Wang Liming,  Feng Qiang,  Zhang Dandan,  Ayiguzaili Tuerdimaimaiti,  Guo Ruru,  Dong Lijie,  Wei Ruihua,  Liu Aihua DOI: 10.3760/cma.j.cn115989-20221101-00509 Published 2024-06-10 Cite as Chin J Exp Ophthalmol, 2024, 42(6): 512-519. Abstract                               [Download PDF] [Read Full Text] Objective To analyze the […]

MeCP2-induced alterations of transcriptome and m6A modification in retinal pigment epithelial cell

Authors: Zhang Yongya,  Li Xiaohua,  Zhao Xueru,  Li Xue DOI: 10.3760/cma.j.cn115989-20230920-00105 Published 2024-05-10 Cite as Chin J Exp Ophthalmol, 2024, 42(5): 408-416. Abstract                              [Download PDF] [Read Full Text] Objective To investigate mRNA and N6-methyladenosine (m6A) changes in retinal pigment epithelium (RPE) cells […]

Regulatory role of heat shock transcription factor 1 in antioxidant and anti-aging function of the retinal pigment epithelial cells

Authors: Jiang Mingjun,  Shang Guohui,  Zhang Fengyan,  Yin Fanxiang,  Xue Mengjiao,  Hu Yanzhong,  Peng Xuyan DOI: 10.3760/cma.j.cn115989-20230905-00093 Published 2024-05-10 Cite as Chin J Exp Ophthalmol, 2024, 42(5): 417-427. Abstract                              [Download PDF] [Read Full Text] Objective To investigate the anti-aging and antioxidant effect […]

Protective effect of Qideng Mingmu capsule on retinal vessels in mice with oxygen-induced retinopathy

Authors: Liu Chunmeng,  Ding Shan,  Dong Xuewen,  Zhao Dandan,  Pu Siyuan,  Pei Li,  Zhang Fuwen DOI: 10.3760/cma.j.cn115989-20220426-00181 Published 2024-05-10 Cite as Chin J Exp Ophthalmol, 2024, 42(5): 428-435. Abstract                              [Download PDF] [Read Full Text] Objective To investigate the effect of Qideng Mingmu […]

Effect of light pattern on dopamine transporter in the guinea pig retina

Authors: Wang Jingjing,  Li Kai,  Xiang Kaidi,  Chen Jun,  Du Linlin,  Yang Jinliuxing,  Liu Sichen,  Wang Ling,  He Xiangui DOI: 10.3760/cma.j.cn115989-20231103-00159 Published 2024-04-10 Cite as Chin J Exp Ophthalmol, 2024, 42(4): 309-314. Abstract                           【Download PDF】 【Read Full Text】 Objective To study the distribution and […]

Changes in m6A demethylase ALKBH5 expression in form-deprivation myopic guinea pigs and its significance

Authors: Xiang Xiaoling,  Liao Xuan,  Meng Jiayu,  Zhou Guimei,  Zhou Hong,  Zhou Xianmei DOI: 10.3760/cma.j.cn115989-20231028-00156 Published 2024-04-10 Cite as Chin J Exp Ophthalmol, 2024, 42(4): 315-321. Abstract                          【Download PDF】 【Read Full Text】 Objective To investigate the alteration of m6A demethylase AlkB homolog 5 (ALKBH5) […]

Targets and validation of Salvia miltiorrhiza in myopia through network pharmacology

Authors: Lu Xiaonan,  Li Jie,  An Guangqi,  Liu Zhenhui,  Liang Chunyu,  Dai Shuzhen DOI: 10.3760/cma.j.cn115989-20231209-00205 Published 2024-04-10 Cite as Chin J Exp Ophthalmol, 2024, 42(4): 322-328. Abstract                            【Download PDF】 【Read Full Text】 Objective To explore and validate the targets of Salvia miltiorrhiza in myopia using […]