Authors: Wang Shanshan, Wang Fenghua DOI: 10.3760/cma.j.issn.2095-0160.2019.11.014 Published 2019-11-10 Cite as Chin J Exp Ophthalmol, 2019,37(11): 926-931. Abstract [View PDF] [Read Full Text] Age-related macular degeneration (AMD) is the major cause of blindness in the elderly, which mainly affects the retinal pigment […]
Tag: Age-related macular degeneration
Effects of ubiqutin-proteasome system in retinopathy and their mechanism
Authors: Wang Shuai, Liu Shengqiang DOI: 10.3760/cma.j.issn.2095-0160.2019.10.015 Published 2019-10-10 Cite as Chin J Exp Ophthalmol, 2019,37(10): 843-848. Abstract [View PDF] [Read Full Text] Ubiquitin-proteasome system (UPS) is the important protein degradation system in eukaryotic cells, participates in cell cycle, gene transcription, antigen-presenting, cell proliferation and differentiation, signal […]
Relationship between macrophage polarization and age-related macular degeneration
Authors: Liu Fang, Li Jiaqing, Ding Xiaoyan DOI: 10.3760/cma.j.issn.2095-0160.2016.01.019 Published 2016-01-10 Cite as Chin J Exp Ophthalmol, 2016,34(1): 89-91. Abstract [Download PDF] [Read Full Text] Age-related macular degeneration (AMD) is one of the leading causes to blindness worldwide in elderly population.Innate immune system elements, such as macrophages and cytokines, […]
Current researches on proteins associated with polypoidal choroidal vasculopathy
Authors: Zhang Yafang, Li Dai DOI: 10.3760/cma.j.issn.2095-0160.2016.03.019 Published 2016-03-10 Cite as Chin J Exp Ophthalmol, 2016,34(3): 284-288. Abstract [Download PDF] [Read Full Text] Polypoidal choroidal vasculopathy (PCV) is one of the ocular fundus diseases and can cause severe visual impairment or blindness.The occurrence of PCV may be related […]
Research progress of autophagy in age-related macular degeneration and retinal detachment
Authors：Xie Jia, Zhu Ruilin, Yang Liu DOI: 10.3760/cma.j.issn.2095-0160.2016.12.021 Published 2016-12-10 Cite as Chin J Exp Ophthalmol, 2016,34(12): 1145-1148. Abstract [Download PDF] [Read Full Text] As a critical self-protection mechanism to maintain the cellular homeostasis and functions, autophagy plays a significant role in growth, adaptation, tumor suppression, aging, innate and acquired […]
Effects of exosomes in pathogenesis of age-related macular degeneration
Authors: Yang Jing, Chen Song DOI: 10.3760/cma.j.issn.2095-0160.2017.01.018 Published 2017-01-10 Cite as Chin J Exp Ophthalmol, 2017,35(1): 83-86. Abstract [Download PDF] [Read Full Text] Exosomes are nanometer membranous vesicles which can be distributed in a variety of biological fluids, including peripheral blood, urine, saliva and so on.Currently, the […]
Pyroptosis and eye disease
Authors: Jin Xin, Zhang Hong DOI: 10.3760/cma.j.issn.2095-0160.2017.12.015 Published 2017-12-10 Cite as Chin J Exp Ophthalmol, 2017,35(12): 1130-1133. Abstract [Download PDF] [Read Full Text] Pyroptosis is a new programmed cell death which has been found recently.Pyroptosis features rapid plasma-membrane rupture and release of pro-inflammatory intracellular contents.Pyroptosis plays a […]
Paying attention to the prognosis guiding effects of CNV dynamic changes based-OCT angiography in neovascular age-related macular degeneration after antiangiogenic therapy
Authors: Zhao Zhi, Sun Xiaodong DOI: 10.3760/cma.j.issn.2095-0160.2018.01.001 Published 2018-01-10 Cite as Chin J Exp Ophthalmol, 2018,36(1): 1-4. Abstract [Download PDF] [Read Full Text] Intravitreal injection of anti-vascular endothelial growth factor (VEGF) agents is a first line therapy for neovascular age-related macular degeneration (nAMD). However, how to predict […]
Analysis of long-term outcomes and causes influencing visual prognosis in eyes receiving anti-VEGF-A for wet age-related macular degeneration
Authors: Yang Shiqi, Sun Xiaodong DOI: 10.3760/cma.j.issn.2095-0160.2018.03.016 Published 2018-03-10 Cite as Chin J Exp Ophthalmol, 2018,36(3): 236-240. Abstract [Download PDF] [Read Full Text] As a progressive chronic disease, age-related macular degeneration (AMD) is the leading cause of blindness worldwide.However, current therapy for AMD shows a dramatic breakthrough.More […]
Research progress of stem cells in the treatment of retinal degenerative diseases
Authors: Zhang Kefan, Qu Xiuxia, Fan Guoping DOI: 10.3760/cma.j.issn.2095-0160.2018.11.011 Published 2018-11-10 Cite as Chin J Exp Ophthalmol, 2018,36(11): 871-877. Abstract [Download PDF] [Read Full Text] Eyes are important human organs, and retinal degenerative diseases can cause irreversible blindness.Up to date, cell transplantation is an important method for the […]