Authors: Yang Huihui, Lei Xiang, Meng Zijun, Liu Huihong, Yu Lu, Yuan Huijuan DOI: 10.3760/cma.j.cn115989-20241128-00327 Published: 2025 -05 -10 Citation Yang Huihui, Lei Xiang, Meng Zijun, et al. Effect of circBPTF targeting miR-224-3p on high glucose induced human retinal vascular endothelial cells injury[J]. Chin J Exp Ophthalmol, 2025, 43(05):422-429. DOI: 10.3760/cma.j.cn115989-20241128-00327. [Download PDF] [View Full Text] ABSTRACT Objective […]
Tag: Apoptosis
Effect of 7, 8-dihydroxyflavone on NMDA-induced apoptosis of retinal ganglion cells
Authors: Zhu Jing, Huang Keke, Guo Juan DOI: 10.3760/cma.j.cn115989-20240201-00030 Published: 2025 -05 -10 Citation Zhu Jing, Huang Keke, Guo Juan. Effect of 7, 8-dihydroxyflavone on NMDA-induced apoptosis of retinal ganglion cells[J]. Chin J Exp Ophthalmol, 2025, 43(05):430-437. DOI: 10.3760/cma.j.cn115989-20240201-00030. [Download PDF] [View Full Text] ABSTRACT Objective To investigate the effect of intravitreal injection of 7, 8-dihydroxyflavone (DHF) on N-methyl-D-aspartate […]
Research progress on the role of lncRNAs in the occurrence and development of glaucoma
Authors: Guan Ruijuan, Yan Xin, Kang Zefeng DOI: 10.3760/cma.j.cn115989-20220221-00068 Published: 2025 -05 -10 Citation Guan Ruijuan, Yan Xin, Kang Zefeng. Research progress on the role of lncRNAs in the occurrence and development of glaucoma[J]. Chin J Exp Ophthalmol, 2025, 43(05):466-470. DOI: 10.3760/cma.j.cn115989-20220221-00068. [Download PDF] [View Full Text] ABSTRACT Glaucoma refers to a group of heterogeneous eye diseases, which […]
Expression of long-chain non-coding RNA-P21 in hydrogen peroxide induced human lens epithelial cells damage
Authors: Dong Xiaoming, Liu Yuxuan, Ji Liyang, Wang Jing, Zhang Jinsong DOI: 10.3760/cma.j.cn115989-20221109-00522 Published 2024-03-10 Cite as Chin J Exp Ophthalmol, 2024, 42(3): 232-239. Abstract [Download PDF] [Read Full Text] Objective To detect the changes in the biological activity and expression of […]
Research progress on the inhibition of photoreceptor cell apoptosis by the pentose phosphate pathway and its molecular mechanism
Authors: Han Siyang, Sun Xiaodong DOI: 10.3760/cma.j.cn115989-20210317-00179 Published 2024-01-10 Cite as Chin J Exp Ophthalmol, 2024, 42(1): 72-75. Abstract [Download PDF] [Read Full Text] Photoreceptor cells are a special type of neuroepithelial cells, which play an important role in the generation and […]
Inhibitory effect of specnuezhenide on high glucose-induced human retinal microvascular endothelial cell injury and its mechanism
Authors: Liu Qian, Feng Xiaomei, Liu Changgeng, Li Haijun, Yang Xiaoyuan, Ren Jing, Zhang Ying DOI: 10.3760/cma.j.cn115989-20211130-00662 Published 2023-04-10 Cite as Chin J Exp Ophthalmol, 2023, 41(4): 312-320. Abstract [Download PDF] [Read Full Text] Objective To investigate the effect of specnuezhenide on […]
Antagonistic effect of SC79 on high glucose-induced apoptosis of RPE cells and its regulatory mechanism on AKT-XIAP signaling pathway
Authors: Zheng Lei, Ma Dahui, Chen Miaohong, Zhang Guoming DOI: 10.3760/cma.j.cn115989-20210710-00405 Published 2023-03-10 Cite as Chin J Exp Ophthalmol, 2023, 41(3): 226-232. Abstract [Download PDF] [Read Full Text] Objective To investigate the antagonistic effect and potential mechanism of specific AKT activator SC79 […]
Promoting effect of AGTR1 blocker olmesartan on the apoptosis of HTF and its mechanism
Authors: Wang Lijun, Li Hongsong, Zhang Wenyi, Shao Meilin, Ren Meimei, Wang Jianming DOI: 10.3760/cma.j.cn115989-20220601-00262 Published 2023-02-10 Cite as Chin J Exp Ophthalmol, 2023, 41(2): 119-126. Abstract [Download PDF] [Read Full Text] Objective To study the effect and mechanism of angiotensin type 1 […]
Inhibitory effects of N-acetylcysteine and salubrinal on apoptosis of retinal pigment epithelial cells induced by all-trans-retinoic acid
Authors: Wu Juan, Cui Dongmei, Zeng Junwen DOI: 10.3760/cma.j.cn115989-20200414-00262 Published 2023-01-10 Cite as Chin J Exp Ophthalmol, 2023, 41(1): 16-21. Abstract [Download PDF] [Read Full Text] Objective To observe the effect of the antioxidant N-acetylcysteine (NAC) and selective endoplasmic […]
Protective effect of tert-butylhydroquinone on retinal morphology and function in early diabetic rats and its mechanism
·Experimental Research· Protective effects of tert-butylhydroquinone on retinal structure, function and mechanism in early diabetic rat models Wang Juan1, Wei Fang2, Cao Yang1, Tian Min1, Lyu Hongbin1 1Department of Ophthalmology, the Affiliated Hospital of Southwest Medical University, Luzhou 646000, China; 2Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, […]