·Experimental Research· Therapeutic effect of anti-IL-12/IL-23 p40 on experimental autoimmune uveitis and associated mechanism Cui Xuexue, Zhang Zhihui, Wu Lingzi, Li Yongtao, Chen Shuang, Chen Nu, Zhang Xiaomin Tianjin Key Laboratory of Retinal Functions and Diseases, Tianjin Branch of National Clinical Research Center for Ocular Disease, Eye Institute and School of Optometry, Tianjin Medical University […]
Tag: Mice
Damage of blue-light exposure to retinal morphology and function in mice
Authors: Yang Daidi, Sun Ruxu, Chen Xue, Liu Qinghuai DOI: 10.3760/cma.j.issn.2095-0160.2020.01.003 Published 2020-01-10 Cite as Chin J Exp Ophthalmol, 2020,38(01): 10-15. Abstract [View PDF] [Read Full Text] Objective To study the damage effects of blue-light exposure on retinal morphology and function in mouse. Methods Twenty 8-week-old […]
Protective effects of folic acid on retina in diabetic mice and its anti-oxidative stress mechanism
Authors: Li Yinglan, Wu Min, Xue Xiaoqin, Li Changxing, Lei Youfang, Dai Dongfang DOI: 10.3760/cma.j.issn.2095-0160.2020.01.005 Published 2020-01-10 Cite as Chin J Exp Ophthalmol, 2020,38(01): 23-30. Abstract [View PDF] [Read Full Text] Objective To explore the protective effects of folic acid on retinas and its anti-oxidative stress […]
Differential expression and bioinformation analysis of retinal proteins in mice with experimental autoimmune uveitis
Authors: Chen Shuang, Shao Xianfeng, Zhang Zhihui, Chen Nu, Wu Lingzi, Cui Xuexue, Li Xiaorong, Zhang Xiaomin DOI: 10.3760/cma.j.issn.2095-0160.2019.12.003 Published 2019-12-10 Cite as Chin J Exp Ophthalmol, 2019,37(12): 949-955. Abstract [View PDF] [Read Full Text] Objective To observe the expression of retinal […]
Expression changes of brain-derived neurotrophic factor in retina of oxygen-induced retinopathy
Authors: Duan Haixia, Guo Kai, Wang Banwei DOI: 10.3760/cma.j.issn.2095-0160.2016.01.011 Published 2016-01-10 Cite as Chin J Exp Ophthalmol, 2016,34(1): 56-59. Abstract [Download PDF] [Read Full Text] Background Neovascular diseases such as retinopathy of prematurity often leads to irreversible vision loss.The study on oxidative damage mechanism is becoming more and […]
Dysfunction of tear film and ultrastructural changes of corneal epithelial cells in castrated male mice
Authors: Li Li, Wang Shuangmei, Zheng Xuan, Kang Qianyan DOI: 10.3760/cma.j.issn.2095-0160.2016.02.002 Published 2016-02-10 Cite as Chin J Exp Ophthalmol, 2016,34(2): 103-107. Abstract [Download PDF] [Read Full Text] Background Studies indicate that the decline of androgen level affects the secretion function of epithelial cells of meibomian glands and lacrimal glands, which […]
Isolation and culture of corneal neovascular endothelial cells and expression of chemokine receptors
Authors: Liu Gaoqin, Xiao Yanhui, Chen Zhigang, Xu Jing, Lu Peirong DOI: 10.3760/cma.j.issn.2095-0160.2016.02.008 Published 2016-02-10 Cite as Chin J Exp Ophthalmol, 2016,34(2): 132-136. Abstract [Download PDF] [Read Full Text] Background The pathogenesis and mechanism research of corneal neovascularization is of important significance for the prevention and management of corneal neovascularization. Some […]
Research progress of Cre/LoxP system in the eyes of animal model
Authors:Lou Xiangfeng, Luo Xue, Shen Yin DOI: 10.3760/cma.j.issn.2095-0160.2019.09.015 Published 2019-09-10 Cite as Chin J Exp Ophthalmol, 2019,37(9): 759-763. Abstract [View PDF] [Read Full Text] Cre/LoxP system has been widely used as new type of gene targeting, which can transform genes in specific tissues and organs, remove specific […]
Promoting effect of Toll like receptor 4 on oxygen-induced retinal neovascularization and its mechanism
Authors: Xu Wenqin, Yin Jie, Wang Yusheng DOI: 10.3760/cma.j.issn.2095-0160.2016.04.007 Published 2016-04-10 Cite as Chin J Exp Ophthalmol, 2016,34(4): 317-323. Abstract [Download PDF] [Read Full Text] Background Studies showed that Toll like receptors (TLRs) play an important role in the development of retinal angiogenesis.However, the effect and […]
Response properties of neurons and synaptic plasticity during pre-critical period of visual development in mouse visual cortex
Authors: Shi Xuefeng, Zhao Kanxing DOI: 10.3760/cma.j.issn.2095-0160.2016.04.003 Published 2016-04-10 Cite as Chin J Exp Ophthalmol, 2016,34(4): 298-304. Abstract [Download PDF] [Read Full Text] Background The visual development is completed during the critical period in human and mammals.However, the critical period is not the initial of receiving […]