Authors: Hong Jiaxu, Xu Jianjiang, Zhou Xujiao DOI: 10.3760/cma.j.cn115989-20220303-00086 Published 2022-12-10 Cite as Chin J Exp Ophthalmol, 2022, 40(12): 1119-1124. Abstract [View PDF] [Read Full Text] Dry eye is becoming more common worldwide.Its pathophysiology is complicated, and its condition is chronic.Treatment options […]
Tag: Oxidative stress
Role of mitophagy in diabetic corneal endothelial lesion
Authors: Chen Chen, Zhou Qingjun, Xie Lixin DOI: 10.3760/cma.j.cn115989-20191211-00539 Published 2022-12-10 Cite as Chin J Exp Ophthalmol, 2022, 40(12): 1181-1185. Abstract [View PDF] [Read Full Text] Diabetic keratopathy is one of the common ocular complications of diabetes, and diabetic patients are often […]
Inhibitory effect of ZhuJing pill variant formula medicated serum on H2O2-induced epithelial-mesenchymal transition of human RPE cells and its mechanism
Authors: Shao Yan, Zhang Yuanzhong, Yang Ning, Hang Li, Chen Chunming, Li Min, Xu Xinrong DOI: 10.3760/cma.j.cn115989-20210907-00501 Published 2022-11-10 Cite asChin J Exp Ophthalmol, 2022, 40(11): 1013-1022. Abstract [View PDF] [Read Full Text] Objective To study the effect of ZhuJing pill variant […]
Correlation between nitric oxide and oxidative stress in diabetic retinopathy
Authors: Wang Juan, Xiang Xiaohong, Lyu Hongbin DOI: 10.3760/cma.j.cn115989-20191206-00528 Published 2022-11-10 Cite asChin J Exp Ophthalmol, 2022, 40(11): 1095-1099. Abstract [View PDF] [Read Full Text] Diabetic retinopathy (DR) is a common microvascular complication of diabetes mellitus, with capillary occlusion, microaneurysms, and […]
Protective effect of myricitrin on retinal microvascular endothelial cells induced by high glucose and its regulation mechanism
·Experimental Research· Protective effect of myricitrin on retinal microvascular endothelial cells induced by high glucose and its regulation mechanism Liu Qian, Liu Changgeng, Li Haijun, Dong Yangzeng, Zhang Ying Department of Ophthalmology, Henan Provincial People’s Hospital, People’ s Hospital of Zhengzhou University, Henan Eye Hospital, Henan Eye Institute, Zhengzhou 450003, China Corresponding author: Liu Qian, […]
Inhibitory effect of siRNA-KCNQ1OT1 on human lens epithelial cell apoptosis by targeting miR-199a-5p
Authors: Lu Cheng, Zhang Fengyan, Zhang Yuhang, Zhang Jiajuan DOI: 10.3760/cma.j.cn115989-20210427-00280 Published 2022-06-10 Cite asChin J Exp Ophthalmol, 2022, 40(6): 514-523. Abstract [View PDF] [Read Full Text] Objective To explore the inhibitory effect of long non-coding RNA (lncRNA) KCNQ1 overlapping transcript […]
Regulation of miR-155 in H2O2-induced oxidative stress in lens epithelial cells via targeting SIRT1
Authors: Niu Yantao, Zhang Li, Xie Wenfang DOI: 10.3760/cma.j.cn115989-20201104-00735 Published 2022-05-10 Cite asChin J Exp Ophthalmol, 2022, 40(5): 404-413. Abstract [View PDF] [Read Full Text] Objective To investigate the role of microRNA (miR)-155 in hydrogen peroxide (H2O2)-induced oxidative stress injury in lens epithelial cells (LECs) […]
Promoting effect of miR-15a on high glucose-induced oxidative stress in human lens epithelial cells and its mechanism
·Experimental Research· Promoting effect of miR-15a on high glucose-induced oxidative stress in human lens epithelial cells and its mechanism Nan Anchao, Nan Jianru, Liu Yadong, Liu Xiangling Department of Ophthalmology, the Second Affiliated Hospital of Zhengzhou University, Zhengzhou 450014, China Corresponding author: Nan Anchao, Email: nananchao0208@163.com Abstract […]
Effect of ROS/NLRP3/Caspase-1 signaling pathway on the apoptosis of retinal pigment epithelial cells induced by high glucose
Authors: Li Hongsong, Li Rong, Wang Lijun, Liao Dingying, Wang Jianming DOI: 10.3760/cma.j.cn115989-20210420-00267-1 Published 2022-01-10 Cite asChin J Exp Ophthalmol, 2022, 40(1): 6-12. Abstract [View PDF] [Read Full Text] Objective To investigate the effect of the nucleotide-binding domain, leucine-rich-containing family, pyrin […]