Tag: Oxidative stress

Inhibitory effect of specnuezhenide on high glucose-induced human retinal microvascular endothelial cell injury and its mechanism

Authors: Liu Qian,  Feng Xiaomei,  Liu Changgeng,  Li Haijun,  Yang Xiaoyuan,  Ren Jing,  Zhang Ying DOI: 10.3760/cma.j.cn115989-20211130-00662 Published 2023-04-10 Cite as Chin J Exp Ophthalmol, 2023, 41(4): 312-320. Abstract                              [Download PDF] [Read Full Text] Objective To investigate the effect of specnuezhenide on […]

Inhibitory effect of phloretin on inflammation and oxidative stress in IL-1β induced orbital fibroblasts in Graves orbitopathy and its mechanism

Authors: Jin Wei,  Zhang Li,  Li Qian,  Ni Yao,  Chai Chang DOI: 10.3760/cma.j.cn115989-20220606-00266 Published 2023-03-10 Cite as Chin J Exp Ophthalmol, 2023, 41(3): 233-240. Abstract                              [Download PDF]  [Read Full Text] Objective To investigate the inhibitory effect of phloretin on inflammation and oxidative […]

Inhibitory effect of ranibizumab on retinal oxidative stress in a rat model of choroidal neovascularization and its mechanism

Authors: Yang Yanzhen,  Zhuang Xianli,  Li Shujie,  Zhang Ying,  Yang Jiagan,  Li Lulu DOI: 10.3760/cma.j.cn115989-20210930-00543 Published 2023-01-10 Cite as Chin J Exp Ophthalmol, 2023, 41(1): 22-28. Abstract                                    [Download PDF] [Read Full Text] Objective To study the effect of ranibizumab […]

Focusing on antioxidant treatment of dry eye and novel drug study

Authors: Hong Jiaxu,  Xu Jianjiang,  Zhou Xujiao DOI: 10.3760/cma.j.cn115989-20220303-00086 Published 2022-12-10 Cite as Chin J Exp Ophthalmol, 2022, 40(12): 1119-1124. Abstract                              [View PDF] [Read Full Text] Dry eye is becoming more common worldwide.Its pathophysiology is complicated, and its condition is chronic.Treatment options […]

Role of mitophagy in diabetic corneal endothelial lesion

Authors: Chen Chen,  Zhou Qingjun,  Xie Lixin DOI: 10.3760/cma.j.cn115989-20191211-00539 Published 2022-12-10 Cite as Chin J Exp Ophthalmol, 2022, 40(12): 1181-1185. Abstract                              [View PDF] [Read Full Text] Diabetic keratopathy is one of the common ocular complications of diabetes, and diabetic patients are often […]

Inhibitory effect of ZhuJing pill variant formula medicated serum on H2O2-induced epithelial-mesenchymal transition of human RPE cells and its mechanism

Authors: Shao Yan,  Zhang Yuanzhong,  Yang Ning,  Hang Li,  Chen Chunming,  Li Min,  Xu Xinrong DOI: 10.3760/cma.j.cn115989-20210907-00501 Published 2022-11-10 Cite asChin J Exp Ophthalmol, 2022, 40(11): 1013-1022. Abstract                            [View PDF] [Read Full Text] Objective To study the effect of ZhuJing pill variant […]

Correlation between nitric oxide and oxidative stress in diabetic retinopathy

Authors: Wang Juan,  Xiang Xiaohong,  Lyu Hongbin DOI: 10.3760/cma.j.cn115989-20191206-00528 Published 2022-11-10 Cite asChin J Exp Ophthalmol, 2022, 40(11): 1095-1099. Abstract                              [View PDF] [Read Full Text] Diabetic retinopathy (DR) is a common microvascular complication of diabetes mellitus, with capillary occlusion, microaneurysms, and […]

Protective effect of myricitrin on retinal microvascular endothelial cells induced by high glucose and its regulation mechanism

·Experimental Research· Protective effect of myricitrin on retinal microvascular endothelial cells induced by high glucose and its regulation mechanism Liu Qian, Liu Changgeng, Li Haijun, Dong Yangzeng, Zhang Ying Department of Ophthalmology, Henan Provincial People’s Hospital, People’ s Hospital of Zhengzhou University, Henan Eye Hospital, Henan Eye Institute, Zhengzhou 450003, China Corresponding author: Liu Qian, […]

Inhibitory effect of siRNA-KCNQ1OT1 on human lens epithelial cell apoptosis by targeting miR-199a-5p

Authors: Lu Cheng,  Zhang Fengyan,  Zhang Yuhang,  Zhang Jiajuan DOI: 10.3760/cma.j.cn115989-20210427-00280 Published 2022-06-10 Cite asChin J Exp Ophthalmol, 2022, 40(6): 514-523. Abstract                              [View PDF]  [Read Full Text] Objective To explore the inhibitory effect of long non-coding RNA (lncRNA) KCNQ1 overlapping transcript […]

Regulation of miR-155 in H2O2-induced oxidative stress in lens epithelial cells via targeting SIRT1

Authors: Niu Yantao,  Zhang Li,  Xie Wenfang DOI: 10.3760/cma.j.cn115989-20201104-00735 Published 2022-05-10 Cite asChin J Exp Ophthalmol, 2022, 40(5): 404-413. Abstract                              [View PDF] [Read Full Text] Objective To investigate the role of microRNA (miR)-155 in hydrogen peroxide (H2O2)-induced oxidative stress injury in lens epithelial cells (LECs) […]