Authors: Kong Deqian, Zheng Guangying, Li Li, Liu Yue, Cai Fangfei DOI: 10.3760/cma.j.issn.2095-0160.2017.03.010 Published 2017-03-10 Cite as Chin J Exp Ophthalmol, 2017,35(3): 233-238. Abstract [Download PDF] [Read Full Text] Background Posterior capsular opacification (PCO) is a primary complication after extracapsular cataract extraction.The mechanism of PCO is associated with proliferation, migration and […]
Tag: Human
Co-expression of GRP78 and Myocilin in trabecular meshwork cells of primary open angle glaucoma
Authors: Chai Fang, Ai Hua, Li Juan, Yang Xinguang DOI: 10.3760/cma.j.issn.2095-0160.2017.04.004 Published 2017-04-10 Cite as Chin J Exp Ophthalmol, 2017,35(4): 300-305. Abstract [Download PDF] [Read Full Text] Background Misfolding of Myocilin protein plays an important role in the pathogenesis of primary open angle glaucoma (POAG). GRP78 can transfer the […]
The promoting effects of insulin-like growth factor 1 on the biological behaviour of human retinal vascular endothelial cells
Authors: Wang Mengjiao, Liu Gaoqin, Xu Jing, Li Dan, Lu Peirong DOI: 10.3760/cma.j.issn.2095-0160.2017.05.007 Published 2017-05-10 Cite as Chin J Exp Ophthalmol, 2017,35(5): 417-422. Abstract [Download PDF] [Read Full Text] Background The suppression of retinal angiogenesis is one of primary treatment targets for retinal vascular diseases, so seeking the intervention targets […]
Protective effects of tissue factor targeting peptide on human retinal pigment epithelial cell damage induced by blue light
Authors: Li Dandan, Zou Xiulan, Chen Jingxia, Xu Zhe, Yu Yongzhen, Zhou Wenjie, Wang Guanfeng, Rao Benqiang, Zou Yuping DOI: 10.3760/cma.j.issn.2095-0160.2017.07.006 Published 2017-07-10 Cite as Chin J Exp Ophthalmol, 2017,35(07): 603-609. Abstract [Download PDF] [Read Full Text] Background Light-induced retinal damage results in the damage of retinl pigment epithelial (RPE) cells and therefore affects […]
Protection effects of metformin on biological behaviour of human vascular endothelial cells under inflammatory conditions
Authors: Han Jing, Yan Xiaolong, Xiaoxi Qiao DOI: 10.3760/cma.j.issn.2095-0160.2017.07.002 Published 2017-07-10 Cite as Chin J Exp Ophthalmol, 2017,35(07): 581-585. Abstract [Download PDF] [Read Full Text] Background Studies showed that inflammatory process participates in the pathogenesis and development of diabetic retinopathy targeting retinal vascular endothelial […]
Genetic analysis of a Chinese family with congenital aniridia and detection of PAX6 mutation locus
Authors: Zhang Luxi, Yang Ge, Jia Jing, Wan Wencui, Yang Xin, Jin Xuemin DOI: 10.3760/cma.j.issn.2095-0160.2017.08.011 Published 2017-08-10 Cite as Chin J Exp Ophthalmol, 2017,35(8): 721-725. Abstract [Download PDF] [Read Full Text] Background Congenital aniridia is a rare bilateral hereditary ophthalmopathy which impact panocular.Researches showed that congenital aniridia can be caused by […]
Mediated effects of endoplasmic reticulum stress on light-induced apoptosis and inflammation of human retinal pigment epithelial cell
Authors: Jiang Wenjing, Zhang Lina, Yu Xiao, Niu Yingjun DOI: 10.3760/cma.j.issn.2095-0160.2017.09.010 Published 2017-09-10 Cite as Chin J Exp Ophthalmol, 2017,35(9): 816-823. Abstract [Download PDF] [Read Full Text] Background The light damage model of retinal pigment epithelium (RPE) cells is a research direction of retinal degeneration diseases, and RPE cell […]
The measurement of macular intraretinal layer volume and its influence factors in normal subjects
Authors: Ruan Jianxiang, Feng Lixia, Chen Ling DOI: 10.3760/cma.j.issn.2095-0160.2017.11.014 Published 2017-11-10 Cite as Chin J Exp Ophthalmol, 2017,35(11): 1025-1029. Abstract [Download PDF] [Read Full Text] Background The histopathological and functional changes are affected by age, gender and axial length (AL). However, whether these factors […]
Effects of transient receptor potential melastatin 7 on dexamethasone-mediated cytoskeletal protein remodeling of trabecular meshwork cells
Authors: Liu Liling, Xu Jiangang, Ouyang Zhikun, Yang Yangfan, Wu Kaili, Yu Minbin DOI: 10.3760/cma.j.issn.2095-0160.2018.04.006 Published 2018-04-10 Cite as Chin J Exp Ophthalmol, 2018,36(4): 259-265. Abstract [Download PDF] [Read Full Text] Objective To investigate the effects of transient receptor potential melastatin (TRPM) 7 on dexamethasone (Dex)-mediated cytoskeleton remodeling in human trabecular […]