Authors: Chen Fei, Ma Jingyu, Yu Wenlu, Luo Lixia, Tan Xuhua DOI: 10.3760/cma.j.cn115989-20260104-00005 Published: 2026 -03 -10 Citation Chen Fei, Ma Jingyu, Yu Wenlu, et al.Role of YAP1 in regulating lens epithelial cell proliferation and cell cycle by binding to the SOX2 promoter[J]. Chin J Exp Ophthalmol, 2026, 44(3):209-217. DOI: 10.3760/cma.j.cn115989-20260104-00005. ABSTRACT […]
Tag: Lens epithelial cells
Inhibitory effect of stachydrine on high glucose-induced apoptosis in human lens epithelial cells and its mechanism
Authors: Wu Guijia, Chen Xiteng, Kou Zhenyu, Gao Nan, Bai Xiaomei, Mao Han, Jiang Yuanfeng, Dong Lijie, Tian Fang DOI: 10.3760/cma.j.cn115989-20240722-00204 Published: 2026 -03 -10 Citation Wu Guijia, Chen Xiteng, Kou Zhenyu, et al. Inhibitory effect of stachydrine on high glucose-induced apoptosis in human lens epithelial cells and its mechanism[J]. Chin J Exp Ophthalmol, 2026, 44(3):218-226. DOI: 10.3760/cma.j.cn115989-20240722-00204. […]
Promotive effect of the TGF-β/WNT5a/JNK signaling pathway on the epithelial-mesenchymal transition in human lens epithelial cells
Authors: Song Yu, Bao Xiuli. Published: 2025 -03 -10 DOI: 10.3760/cma.j.cn115989-20230425-00147 Citation Song Yu, Bao Xiuli. Promotive effect of the TGF-β/WNT5a/JNK signaling pathway on the epithelial-mesenchymal transition in human lens epithelial cells[J]. Chin J Exp Ophthalmol, 2025, 43(3):219-226. DOI: 10.3760/cma.j.cn115989-20230425-00147. [Download PDF] [View Full Text] ABSTRACT Objective To investigate the effects of the transforming growth factor-β/Wingless 5a/c-Jun N-terminal […]
Expression of long-chain non-coding RNA-P21 in hydrogen peroxide induced human lens epithelial cells damage
Authors: Dong Xiaoming, Liu Yuxuan, Ji Liyang, Wang Jing, Zhang Jinsong DOI: 10.3760/cma.j.cn115989-20221109-00522 Published 2024-03-10 Cite as Chin J Exp Ophthalmol, 2024, 42(3): 232-239. Abstract [Download PDF] [Read Full Text] Objective To detect the changes in the biological activity and expression of […]
Inhibitory effect of indocyanine green on biological behavior and transdifferentiation of human lens epithelial cells and its mechanism
Authors: Liu Yajun, Zhao Yingdi, Zhang Wenwen, Zhang Si, He Zifang, Chen Feifei, Xie Zhenggao DOI: 10.3760/cma.j.cn115989-20220817-00380 Published 2023-12-10 Cite as Chin J Exp Ophthalmol, 2023, 41(12): 1160-1168. Abstract [Download PDF] [Read Full Text] Objective To investigate the inhibitory effect of indocyanine […]
Inhibitory effect of astaxanthin on oxidative stress damage in lens epithelial cells and its mechanism
Authors: Li Yong, Liu Zhaochen, Peng Huacong DOI: 10.3760/cma.j.cn115989-20200624-00448 Published 2023-05-10 Cite as Chin J Exp Ophthalmol, 2023, 41(5): 428-435. Abstract [Download PDF] [Read Full Text] Objective To investigate the regulatory effect of astaxanthin on oxidative stress injury induced by hydrogen peroxide […]
Establishment of lens opacity model in Grx2 knockout mice based on CRISPR/cas9 system and the role of Grx2 in the pathogenesis of cataract
·Experimental Research· Establishment of a lens opacity model in Grx2 knockout mice based on the CRISPR/cas9 system and the role of Grx2 in cataract pathogenesis Guo Yong1, Guo Chenjun2, Zhang Jie2, Ning Xiaona2, Chen Xi3, Yan Hong1 1Department of Ophthalmology, Xi’an People’s Hospital, Xi’an Fourth Hospital, Shaanxi Eye Hospital, Xi’an 710004, China; 2Department of Ophthalmology, […]
Inhibitory effect of microRNA-23b-3p on high glucose-induced autophagy and apoptosis of human lens epithelial cells and its mechanism
·Experimental Research· Role and mechanism of microRNA-23b-3p in regulating high glucose-induced autophagy and apoptosis of human lens epithelial cells Liu Wenlan, Wang Li, Yang Yang, Yan Jin School of Medical Technology, Xi’an Medical University, Xi’an 710021, China Corresponding author: Wang Li, Email: 63148645@qq.com [Abstract] […]
Inhibition of lens epithelial cell migration using different square-edge intraocular lenses in an in vitro capsular bag model
Authors: Lian Feiyue, Li Yang, Jiang Lingfeng, Shen Haoyue, Zhao Jiangyue, Yan Xiaoxiao, Yu Jiaming, Qin Yu DOI: 10.3760/cma.j.cn115989-20200514-00346 Published 2022-05-10 Cite asChin J Exp Ophthalmol, 2022, 40(5): 395-402. Abstract [View PDF] [Read Full Text] Objective To establish an in vitro […]
Regulation of miR-155 in H2O2-induced oxidative stress in lens epithelial cells via targeting SIRT1
Authors: Niu Yantao, Zhang Li, Xie Wenfang DOI: 10.3760/cma.j.cn115989-20201104-00735 Published 2022-05-10 Cite asChin J Exp Ophthalmol, 2022, 40(5): 404-413. Abstract [View PDF] [Read Full Text] Objective To investigate the role of microRNA (miR)-155 in hydrogen peroxide (H2O2)-induced oxidative stress injury in lens epithelial cells (LECs) […]