Tag: Oxidative stress

Inhibitory effects of ghrelin on oxidative stress and ferroptosis in retinal microvascular endothelial cells under high glucose

Authors: Li Rong, Zhang Min, Yan Jiejing DOI: 10.3760/cma.j.cn115989-20240228-00055 Published: 2024-11-10 Citation Li Rong, Zhang Min, Yan Jiejing. Inhibitory effects of ghrelin on oxidative stress and ferroptosis in retinal microvascular endothelial cells under high glucose[J]. Chin J Exp Ophthalmol, 2024, 42(11):991-996. DOI: 10.3760/cma.j.cn115989-20240228-00055. ABSTRACT                  [Download PDF] [Read […]

Role of retinal pigment epithelium-derived extracellular vesicles in the pathogenesis of age-related macular degeneration

Authors: Gao Youge, Wang Yange, Song Zongming DOI:  10.3760/cma.j.cn115989-20230626-00022 Published: 2024 -09 -10 Citation: Gao YG, Wang YG, Song ZM. Role of retinal pigment epithelium-derived extracellular vesicles in the pathogenesis of age-related macular degeneration[J]. Chin J Exp Ophthalmol,2024,42(9):876-880. DOI: 10.3760/cma.j.cn115989-20230626-00022. ABSTRACT        [Download PDF] [Read Full Text]  Age-related macular degeneration (AMD) is one of the main […]

Inhibitory effect of ferulic acid on the retina of diabetic mice and high glucose-induced human retinal pigment epithelium cell injury and the mechanism

Authors: Zhu Dejun,  Zou Wenqing,  Cao Xiangmei,  Wang Xiaofei,  Lu Zhaogang DOI: 10.3760/cma.j.cn115989-20231114-00173 Published 2024-08-10 Cite as Chin J Exp Ophthalmol, 2024, 42(8): 705-715. Abstract                                        [Download PDF] [Read Full Text] Objective To investigate the inhibitory effect of […]

Pathogenic role and mechanism of NADPH oxidase 4 in type 1 diabetic keratopathy mouse

Authors: Zhao Wenxin,  Zhang Xian,  Qin Yazhou,  Zhang Ming,  Gao Ning,  Qin Li,  Li Jingming DOI: 10.3760/cma.j.cn115989-20200320-00188 Published 2024-07-10 Cite as Chin J Exp Ophthalmol, 2024, 42(7): 602-612. Abstract                             【Download PDF】【Read Full Text】 Objective To investigate the pathogenic role and possible mechanism of […]

Regulatory role of heat shock transcription factor 1 in antioxidant and anti-aging function of the retinal pigment epithelial cells

Authors: Jiang Mingjun,  Shang Guohui,  Zhang Fengyan,  Yin Fanxiang,  Xue Mengjiao,  Hu Yanzhong,  Peng Xuyan DOI: 10.3760/cma.j.cn115989-20230905-00093 Published 2024-05-10 Cite as Chin J Exp Ophthalmol, 2024, 42(5): 417-427. Abstract                              [Download PDF] [Read Full Text] Objective To investigate the anti-aging and antioxidant effect […]

Expression of long-chain non-coding RNA-P21 in hydrogen peroxide induced human lens epithelial cells damage

Authors: Dong Xiaoming,  Liu Yuxuan,  Ji Liyang,  Wang Jing,  Zhang Jinsong DOI: 10.3760/cma.j.cn115989-20221109-00522 Published 2024-03-10 Cite as Chin J Exp Ophthalmol, 2024, 42(3): 232-239. Abstract                               [Download PDF] [Read Full Text] Objective To detect the changes in the biological activity and expression of […]

Research progress on the inhibition of photoreceptor cell apoptosis by the pentose phosphate pathway and its molecular mechanism

Authors: Han Siyang,  Sun Xiaodong DOI: 10.3760/cma.j.cn115989-20210317-00179 Published 2024-01-10 Cite as Chin J Exp Ophthalmol, 2024, 42(1): 72-75. Abstract                              [Download PDF] [Read Full Text] Photoreceptor cells are a special type of neuroepithelial cells, which play an important role in the generation and […]

Aging and age-related macular degeneration

Authors: Lei Yi,  Yan Hua DOI: 10.3760/cma.j.cn115989-20200602-00392 Published 2024-01-10 Cite as Chin J Exp Ophthalmol, 2024, 42(1): 76-79. Abstract                             [Download PDF] [Read Full Text] With the aging of the population in modern society, the incidence of age-related diseases increases gradually, especially the age-related […]

Review Effects of the Nrf2 signaling pathway on the occurrence and development of cataract

Authors: Chen Yueqin,  Xue Chunyan DOI: 10.3760/cma.j.cn115989-20210323-00200 Published 2023-06-10 Cite as Chin J Exp Ophthalmol, 2023, 41(6): 607-611. Abstract                              [Download PDF] [Read Full Text]    Cataract is the leading cause of blindness worldwide, and the common mechanism for its onset and development […]

Inhibitory effect of astaxanthin on oxidative stress damage in lens epithelial cells and its mechanism

Authors: Li Yong,  Liu Zhaochen,  Peng Huacong DOI: 10.3760/cma.j.cn115989-20200624-00448 Published 2023-05-10 Cite as Chin J Exp Ophthalmol, 2023, 41(5): 428-435. Abstract                              [Download PDF] [Read Full Text] Objective To investigate the regulatory effect of astaxanthin on oxidative stress injury induced by hydrogen peroxide […]