Tag: Oxidative stress

Regulatory role of heat shock transcription factor 1 in antioxidant and anti-aging function of the retinal pigment epithelial cells

Authors: Jiang Mingjun,  Shang Guohui,  Zhang Fengyan,  Yin Fanxiang,  Xue Mengjiao,  Hu Yanzhong,  Peng Xuyan DOI: 10.3760/cma.j.cn115989-20230905-00093 Published 2024-05-10 Cite as Chin J Exp Ophthalmol, 2024, 42(5): 417-427. Abstract                              [Download PDF] [Read Full Text] Objective To investigate the anti-aging and antioxidant effect […]

Expression of long-chain non-coding RNA-P21 in hydrogen peroxide induced human lens epithelial cells damage

Authors: Dong Xiaoming,  Liu Yuxuan,  Ji Liyang,  Wang Jing,  Zhang Jinsong DOI: 10.3760/cma.j.cn115989-20221109-00522 Published 2024-03-10 Cite as Chin J Exp Ophthalmol, 2024, 42(3): 232-239. Abstract                               [Download PDF] [Read Full Text] Objective To detect the changes in the biological activity and expression of […]

Research progress on the inhibition of photoreceptor cell apoptosis by the pentose phosphate pathway and its molecular mechanism

Authors: Han Siyang,  Sun Xiaodong DOI: 10.3760/cma.j.cn115989-20210317-00179 Published 2024-01-10 Cite as Chin J Exp Ophthalmol, 2024, 42(1): 72-75. Abstract                              [Download PDF] [Read Full Text] Photoreceptor cells are a special type of neuroepithelial cells, which play an important role in the generation and […]

Aging and age-related macular degeneration

Authors: Lei Yi,  Yan Hua DOI: 10.3760/cma.j.cn115989-20200602-00392 Published 2024-01-10 Cite as Chin J Exp Ophthalmol, 2024, 42(1): 76-79. Abstract                             [Download PDF] [Read Full Text] With the aging of the population in modern society, the incidence of age-related diseases increases gradually, especially the age-related […]

Review Effects of the Nrf2 signaling pathway on the occurrence and development of cataract

Authors: Chen Yueqin,  Xue Chunyan DOI: 10.3760/cma.j.cn115989-20210323-00200 Published 2023-06-10 Cite as Chin J Exp Ophthalmol, 2023, 41(6): 607-611. Abstract                              [Download PDF] [Read Full Text]    Cataract is the leading cause of blindness worldwide, and the common mechanism for its onset and development […]

Inhibitory effect of astaxanthin on oxidative stress damage in lens epithelial cells and its mechanism

Authors: Li Yong,  Liu Zhaochen,  Peng Huacong DOI: 10.3760/cma.j.cn115989-20200624-00448 Published 2023-05-10 Cite as Chin J Exp Ophthalmol, 2023, 41(5): 428-435. Abstract                              [Download PDF] [Read Full Text] Objective To investigate the regulatory effect of astaxanthin on oxidative stress injury induced by hydrogen peroxide […]

Inhibitory effect of specnuezhenide on high glucose-induced human retinal microvascular endothelial cell injury and its mechanism

Authors: Liu Qian,  Feng Xiaomei,  Liu Changgeng,  Li Haijun,  Yang Xiaoyuan,  Ren Jing,  Zhang Ying DOI: 10.3760/cma.j.cn115989-20211130-00662 Published 2023-04-10 Cite as Chin J Exp Ophthalmol, 2023, 41(4): 312-320. Abstract                              [Download PDF] [Read Full Text] Objective To investigate the effect of specnuezhenide on […]

Inhibitory effect of phloretin on inflammation and oxidative stress in IL-1β induced orbital fibroblasts in Graves orbitopathy and its mechanism

Authors: Jin Wei,  Zhang Li,  Li Qian,  Ni Yao,  Chai Chang DOI: 10.3760/cma.j.cn115989-20220606-00266 Published 2023-03-10 Cite as Chin J Exp Ophthalmol, 2023, 41(3): 233-240. Abstract                              [Download PDF]  [Read Full Text] Objective To investigate the inhibitory effect of phloretin on inflammation and oxidative […]

Inhibitory effect of ranibizumab on retinal oxidative stress in a rat model of choroidal neovascularization and its mechanism

Authors: Yang Yanzhen,  Zhuang Xianli,  Li Shujie,  Zhang Ying,  Yang Jiagan,  Li Lulu DOI: 10.3760/cma.j.cn115989-20210930-00543 Published 2023-01-10 Cite as Chin J Exp Ophthalmol, 2023, 41(1): 22-28. Abstract                                    [Download PDF] [Read Full Text] Objective To study the effect of ranibizumab […]

Focusing on antioxidant treatment of dry eye and novel drug study

Authors: Hong Jiaxu,  Xu Jianjiang,  Zhou Xujiao DOI: 10.3760/cma.j.cn115989-20220303-00086 Published 2022-12-10 Cite as Chin J Exp Ophthalmol, 2022, 40(12): 1119-1124. Abstract                              [View PDF] [Read Full Text] Dry eye is becoming more common worldwide.Its pathophysiology is complicated, and its condition is chronic.Treatment options […]