Tag: Oxidative stress

Inhibitory effect of siRNA-KCNQ1OT1 on human lens epithelial cell apoptosis by targeting miR-199a-5p

Authors: Lu Cheng,  Zhang Fengyan,  Zhang Yuhang,  Zhang Jiajuan DOI: 10.3760/cma.j.cn115989-20210427-00280 Published 2022-06-10 Cite asChin J Exp Ophthalmol, 2022, 40(6): 514-523. Abstract                              [View PDF]  [Read Full Text] Objective To explore the inhibitory effect of long non-coding RNA (lncRNA) KCNQ1 overlapping transcript […]

Regulation of miR-155 in H2O2-induced oxidative stress in lens epithelial cells via targeting SIRT1

Authors: Niu Yantao,  Zhang Li,  Xie Wenfang DOI: 10.3760/cma.j.cn115989-20201104-00735 Published 2022-05-10 Cite asChin J Exp Ophthalmol, 2022, 40(5): 404-413. Abstract                              [View PDF] [Read Full Text] Objective To investigate the role of microRNA (miR)-155 in hydrogen peroxide (H2O2)-induced oxidative stress injury in lens epithelial cells (LECs) […]

Promoting effect of miR-15a on high glucose-induced oxidative stress in human lens epithelial cells and its mechanism

·Experimental Research· Promoting effect of miR-15a on high glucose-induced oxidative stress in human lens epithelial cells and its mechanism Nan Anchao, Nan Jianru, Liu Yadong, Liu Xiangling Department of Ophthalmology, the Second Affiliated Hospital of Zhengzhou University, Zhengzhou 450014, China Corresponding author: Nan Anchao, Email: nananchao0208@163.com Abstract                  […]

Effect of ROS/NLRP3/Caspase-1 signaling pathway on the apoptosis of retinal pigment epithelial cells induced by high glucose

Authors: Li Hongsong,  Li Rong,  Wang Lijun,  Liao Dingying,  Wang Jianming DOI: 10.3760/cma.j.cn115989-20210420-00267-1 Published 2022-01-10 Cite asChin J Exp Ophthalmol, 2022, 40(1): 6-12. Abstract                              [View PDF]  [Read Full Text] Objective To investigate the effect of the nucleotide-binding domain, leucine-rich-containing family, pyrin […]