·Experimental research· Meibomian gland dysfunction and expressions of inflammatory factors and lipid metabolic factors in diabetic mice Zou Yuanyuan, Liu Xuemei, Qi Yuanyuan, Zhao Shaozhen Tianjin Key Laboratory of Retinal Functions and Diseases, Tianjin Branch of National Clinical Research Center for Ocular Disease, Eye Institute and School of Optometry, Tianjin Medical University Eye Hospital, Tianjin […]
Category: Experimental Science
Therapeutic effect of anti-IL-12/IL-23 p40 on experimental autoimmune uveitis and its mechanism
·Experimental Research· Therapeutic effect of anti-IL-12/IL-23 p40 on experimental autoimmune uveitis and associated mechanism Cui Xuexue, Zhang Zhihui, Wu Lingzi, Li Yongtao, Chen Shuang, Chen Nu, Zhang Xiaomin Tianjin Key Laboratory of Retinal Functions and Diseases, Tianjin Branch of National Clinical Research Center for Ocular Disease, Eye Institute and School of Optometry, Tianjin Medical University […]
Immunoregulatory effects of miR-31-5p overexpression on peripheral blood Th17 cell in a rabbit model of autoimmune dry eye
Authors: Gao Min, Zhao Lu, Chen Sisi, Wei Ruihua, Nian Hong DOI: 10.3760/cma.j.cn115989-20210809-00452 Published 2022-08-10 Cite asChin J Exp Ophthalmol, 2022, 40(8): 716-723. Abstract [View PDF] [Read Full Text] Objective To investigate the immunoregulatory effects of lentivirus-mediated microRNA (miR)-31-5p overexpression on peripheral […]
Inhibitory effect of RMT1-10-induced tolerogenic dendritic cells in vitro on high-risk corneal allograft rejection in mice and its mechanism
Authors: Zhao Min, Yang Liuqing, Wang Mengyu, Tao Yu, Guo Yongyue, Su Ruifeng, Shi Jing, Tan Xiaobo DOI: 10.3760/cma.j.cn115989-20201228-00868 Published 2022-08-10 Cite asChin J Exp Ophthalmol, 2022, 40(8): 725-733. Abstract [View PDF] [Read Full Text] Objective To investigate the inhibitory effect of […]
Inhibitory effect of vorinostat encapsulated hydroxypropyl-β-cyclodextrin eye drops on corneal neovascularization induced by alkali burns in mouse
Authors: Yang Jingjing, Liang Zhen, Lu Ping, Zhang Zhen, Zhang Junjie DOI: 10.3760/cma.j.cn115989-20200807-00566 Published 2022-07-10 Cite asChin J Exp Ophthalmol, 2022, 40(7): 609-616. Abstract [View PDF] [Read Full Text] Objective To prepare vorinostat encapsulated hydroxypropyl-β-cyclodextrin (SAHA-CD) eye drops and investigate its inhibitory […]
Differential expression analysis of circular RNA in human retinal vascular endothelial cells induced by high glucose
·Experimental Research· Differential expression analysis of circular RNA in human retinal vascular endothelial cells induced by high glucose Jia Yangxue1, Wang Zhiling2, Wei Yingying2, Zhu Kai2, Gu Yonghao2 1Department of Ophthalmology, Second Affiliated Hospital of Wannan Medical College, Wuhu 241000, China; 2Department of Ophthalmology, Provincial Hospital Affiliated to Anhui Medical University, Hefei 230001, China Corresponding […]
Protective effect of myricitrin on retinal microvascular endothelial cells induced by high glucose and its regulation mechanism
·Experimental Research· Protective effect of myricitrin on retinal microvascular endothelial cells induced by high glucose and its regulation mechanism Liu Qian, Liu Changgeng, Li Haijun, Dong Yangzeng, Zhang Ying Department of Ophthalmology, Henan Provincial People’s Hospital, People’ s Hospital of Zhengzhou University, Henan Eye Hospital, Henan Eye Institute, Zhengzhou 450003, China Corresponding author: Liu Qian, […]
Effects of different intensity of lighting on refractive development and form deprivation myopia in guinea pigs
Authors: Li Congying, Gan Jiahe, Wang Meijun, Cao Beihe, Huang Ying, He Xi, Hua Ziyu, Sun Minghao, Li Shiming DOI: 10.3760/cma.j.cn115989-20220228-00079 Published 2022-06-10 Cite asChin J Exp Ophthalmol, 2022, 40(6): 491-497. Abstract [View PDF] [Read Full Text] Objective To investigate the […]
Inhibitory effect of siRNA-Pax6 on biological behavior and epithelial-mesenchymal transition of human lens epithelial cells
Authors: Zheng Yuxing, Yang Xiaoxi, Yi Guoguo, Wu Shuduan, Feng Zhizhen, Xia Zhaoxia DOI: 10.3760/cma.j.cn115989-20210423-00272 Published 2022-06-10 Cite asChin J Exp Ophthalmol, 2022, 40(6): 499-506. Abstract [View PDF] [Read Full Text] Objective To explore the effect of […]
Inhibitory effects of NADPH oxidase 4 inhibitor on the epithelial-mesenchymal transition of human RPE cells induced by bevacizumab
Auhtors: Xie Chaohui, Hao Xianghui, Yang Lingling, Xu Haifeng DOI: 10.3760/cma.j.cn115989-20210407-00234 Published 2022-06-10 Cite asChin J Exp Ophthalmol, 2022, 40(6): 507-513. Abstract [View PDF] [Read Full Text] Objective To observe the influence of nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (NOX) 4 […]