Tag: Apoptosis

Promoting effect of miR-15a on high glucose-induced oxidative stress in human lens epithelial cells and its mechanism

·Experimental Research· Promoting effect of miR-15a on high glucose-induced oxidative stress in human lens epithelial cells and its mechanism Nan Anchao, Nan Jianru, Liu Yadong, Liu Xiangling Department of Ophthalmology, the Second Affiliated Hospital of Zhengzhou University, Zhengzhou 450014, China Corresponding author: Nan Anchao, Email: nananchao0208@163.com Abstract                  […]

Inhibitory effect of CLC-2 chloride channel targeted blocking on fibrosis of human conjunctival fibroblasts

Authors: Wu Sharengaowa,  Cui Renzhe,  Lu Di,  Ding Haoxuan,  Sun Lixia DOI: 10.3760/cma.j.cn115989-20200609-00410 Published 2022-04-10 Cite asChin J Exp Ophthalmol, 2022, 40(4): 294-302. Abstract                              [View PDF] [Read Full Text] Objective To investigate the inhibitory effect of CLC-2 chloride channel targeted blocking on fibrosis of human […]

Effect of human umbilical cord derived mesenchymal stem cells on apoptosis of rat retinal ganglion cells under high glucose and on the regulation of p38MAPK pathway

Authors: Liu Xi,  Sun Xiaoping,  Yang Jianwei,  Zhu Dongmei,  Wang Yuan DOI: 10.3760/cma.j.cn115989-20200804-00559 Published 2022-01-10 Cite asChin J Exp Ophthalmol, 2022, 40(1): 21-28. Abstract                              [View PDF] [Read Full Text] Objective To investigate the effect of human umbilical cord mesenchymal stem cells (hUC-MSC) […]

Feasibility of cryopreservation of human corneal stromal lenticules

Authors: Wei Qi,  Ding Hui,  Zhong Tan,  Yu Hanyang,  Yang Zhenduo,  Fan Hongming,  He Linyi,  Zhong Xingwu DOI: 10.3760/cma.j.cn115989-20210413-00249 Published 2021-12-10 Cite asChin J Exp Ophthalmol, 2021, 39(12): 1031-1037. Abstract                              [View PDF] [Read Full Text] Objective To observe the transparency and tissue structure changes of […]

Role of hydrogen sulfide in the pathogenesis of diabetic retinopathy

Authors: Chen Fei,  Zhang Xuedong DOI: 10.3760/cma.j.cn115989-20210914-00512 Published 2021-12-10 Cite asChin J Exp Ophthalmol, 2021, 39(12): 1124-1128. Abstract                              [View PDF] [Read Full Text] Diabetic retinopathy (DR) is a common and important ocular complication of diabetes and has become one of the leading blindness diseases in […]

Comparison of the effects of different intraocular infusion solutions on histology and function of retina

Authors: Zhu Li,  Miao Heng,  Hu Qinrui,  Liu Zhiming,  Bai Yujing,  Yu Youzhi,  Fu Yafei,  Xia Huika,  Huang Lvzhen,  Qi Yun,  Deng Xun,  Li Yan,  Li Xiaoxin DOI: 10.3760/cma.j.cn115989-20200810-00575 Published 2021-11-10 Cite asChin J Exp Ophthalmol, 2021, 39(11): 957-967. Abstract                              [View PDF] [Read Full Text] […]

Research progress of autophagy in the pathogenesis of glaucoma

Authors: Xu Yaohan,  Han Wei DOI: 10.3760/cma.j.cn115989-20210712-00407 Published 2021-10-10 Cite asChin J Exp Ophthalmol, 2021, 39(10): 923-928. Abstract                               [View PDF] [Read Full Text] Glaucoma, a neurodegenerative disease characterized by progressive death of retinal ganglion cells (RGCs) and chronic axonal degeneration, is often associated with elevated […]

Protective effect of adeno-associated virus vector mediated heme oxygenase-1 overexpression on retinitis pigmentosa in rats

Authors: Liang Yuping,  Chen Weiqi,  Hong Yu,  Gao Xiuyun,  Guo Maosheng DOI: 10.3760/cma.j.cn115989-20201108-00754 Published 2021-08-10 Cite asChin J Exp Ophthalmol, 2021, 39(8): 693-699. Abstract                              [View PDF] [Read Full Text] Objective To investigate the protective effect of adeno-associated virus (AAV) vector-mediated heme oxygenase-1 (HO-1) gene overexpression […]

Role and mechanism of Müller cells in diabetic macular edema

Authors: Zhu Shaojin,  Fang Yan DOI: 10.3760/cma.j.cn115989-20200226-00111 Published 2021-04-10 Cite asChin J Exp Ophthalmol, 2021, 39(4): 360-364. Abstract                              [View PDF] [Read Full Text] Müller cells, as the special radial glial cells in the retina, span the entire retina, contact with neurons, microvessels and processes in […]

Biocompatibility of fibrin sealant and human corneal fibroblasts

Authors: Ye Qing,  Jiang Linzhi,  Chen Wenlin,  Zhang Wei,  Zeng Jing DOI: 10.3760/cma.j.cn115989-20190605-00244 Published 2021-02-10 Cite as Chin J Exp Ophthalmol, 2021,39(02): 113-118. Abstract                               [View PDF] [Read Full Text] Objective To study the biocompatibility of fibrin sealant (FS) and human corneal fibroblasts (HCFs) obtained by […]