Tag: Oxidative stress

Anti-oxidative stress effects of miR-125b on lens epithelial cells and its mechanism

Authors: Li Xiang,  Zhang Ying,  Huang Yalin,  Wu Zhong,  Guo Haoyi DOI: 10.3760/cma.j.cn115989-20191022-00458 Published 2021-04-10 Cite asChin J Exp Ophthalmol, 2021, 39(4): 280-288. Abstract                              [View PDF] [Read Full Text] Objective To investigate the anti-oxidative stress effects of microRNA 125b (miR-125b) on lens epithelial cells (LECs) […]

Protective effect of vitexin on retinal ganglion cells in rat retinal ischemia-reperfusion injury model

Authors: Li Manli,  Fan Ke,  Cui Hongpei DOI: 10.3760/cma.j.cn115989-20200509-00319 Published 2021-03-10 Cite as Chin J Exp Ophthalmol, 2021, 39(3): 191-197. Abstract                               [View PDF] [Read Full Text] Objective To explore the protective effect of vitexin on retinal ganglion stem cells (RGCs) from oxidative stress caused by […]

Safe dose of 650 nm low-power semiconductor laser irradiation in chicken retina

Authors: Wang Yipeng,  Chen Song,  Yang Wenchao,  Kong Jiahui DOI: 10.3760/cma.j.cn115989-20200519-00359 Published 2020-07-10 Cite as Chin J Exp Ophthalmol, 2020,38(07): 573-580. Abstract                              [View PDF] [Read Full Text] Objective To observe whether there was a chronic light damage after the irradiation of 650 […]

Antioxidative effect and mechanism of tert-butyl hydroquinone on rat retinal Müller cells under high glucose condition

Authors:He Wei,  Tian Min,  Yu Xi,  Cao Yang,  Zheng Wenli,  Lyu Hongbin DOI: 10.3760/cma.j.issn.2095-0160.2020.01.004 Published 2020-01-10 Cite as Chin J Exp Ophthalmol, 2020,38(01): 16-22. Abstract                              [View PDF]  [Read Full Text]  Objective To expore the impact of teniary butyl hydroquinone (tBHQ) on Müller […]

Protective effects of folic acid on retina in diabetic mice and its anti-oxidative stress mechanism

Authors: Li Yinglan,  Wu Min,  Xue Xiaoqin,  Li Changxing,  Lei Youfang,  Dai Dongfang DOI: 10.3760/cma.j.issn.2095-0160.2020.01.005 Published 2020-01-10 Cite as Chin J Exp Ophthalmol, 2020,38(01): 23-30. Abstract                               [View PDF]  [Read Full Text]  Objective To explore the protective effects of folic acid on retinas and its anti-oxidative stress […]

Anti-apoptotic mechanism of heme oxygenase 1 and its protective role in related ophthalmopathy

Authors: Chen Weiqi,  Hong Yu DOI: 10.3760/cma.j.issn.2095-0160.2020.01.015 Published 2020-01-10 Cite as Chin J Exp Ophthalmol, 2020,38(01): 73-76. Abstract                               [View PDF]  [Read Full Text]  Heme oxygenase 1 (HO-1) is a stress response protein, and its anti-apoptosis research becomes a new hot spot.In recent years, HO-1 plays an […]

Promoting effect of p75NTR receptor overexpression on oxidative stress injury in human retinal pigment epithelium cells

Authors: Qi Yun,  Bai Yujing,  Li Xiaoxin,  Shi Xuan DOI: 10.3760/cma.j.issn.2095-0160.2016.01.004 Published 2016-01-10 Cite as Chin J Exp Ophthalmol, 2016,34(1): 17-23. Abstract                            [Download PDF] [Read Full Text] Background Choroidal neovascularization (CNV) is the primary pathogenic cause of many fundus diseases.Oxidative stress injury of retinal pigment epithelial (RPE) cells plays important […]

Oxidative injury on trabecular meshwork

Authors: Sun Ruizhu,  Zhang Shaodan,  Liang Yuanbo DOI: 10.3760/cma.j.issn.2095-0160.2016.04.019 Published 2016-04-10 Cite as Chin J Exp Ophthalmol, 2016,34(4): 375-379. Abstract                            [Download PDF] [Read Full Text] Glaucoma is a group of neurodegenerative disease characterized by progressive retinal ganglion cells (RGCs) death and visual field defect.Although its pathological mechanism […]

Progress on Nrf2 pathway in diabetic retinopathy

Authors: Zhang Siyuan,  Lyu Hongbin DOI: 10.3760/cma.j.issn.2095-0160.2016.05.017 Published 2016-05-10 Cite as Chin J Exp Ophthalmol, 2016,34(5): 471-475. Abstract                              [Download PDF] [Read Full Text] Diabetic retinopathy (DR) is a serious complication of diabetes mellitus, which leads to vision loss or even blindness.Nuclear factor erythroid 2-related factor 2 […]

Induction of docosahexaenoic acid to expression of heme oxygenase-1 in retinal pigment epithelial cells

Authors: Liu Yuefeng,  Luo Weimin,  Zhang Yong,  Zhong Xiaodong DOI: 10.3760/cma.j.issn.2095-0160.2016.08.002 Published 2016-08-10 Cite as Chin J Exp Ophthalmol, 2016,34(8): 677-683. Abstract                            [Download PDF] [Read Full Text] Background Oxydative stress is an important pathogenesis of age-related macular degeneration.Resent evidences indicate that docosahexaenoic acid (DHA) plays an important […]