Authors: Chen Xuhao, Hong Ying, Zhang Chun DOI: 10.3760/cma.j.cn115989-20190926-00417 Published 2022-04-10 Cite asChin J Exp Ophthalmol, 2022, 40(4): 371-377. Abstract [View PDF] [Read Full Text] Microcirculation alterations of the human retina are of significant relevance with glaucoma.Optical coherence tomography angiography (OCTA) is a non-invasive examination […]
Tag: Retina
Promoting effects of Difrarel® on retinal function following panretinal photocoagulation in diabetic retinopathy
Authors: Zhang Moli, Wei Wenbin, Tian Bei DOI: 10.3760/cma.j.cn115989-20210325-00205 Published 2022-03-10 Cite asChin J Exp Ophthalmol, 2022, 40(3): 247-252. Abstract [View PDF] [Read Full Text] Objective To investigate the promoting effect of Difrarel® on retinal function following panretinal photocoagulation (PRP) in the eyes with diabetic […]
Role of retinal microglia-mediated parainflammation in age-related macular degeneration
Authors: Wang Yuwei, Li Jing DOI: 10.3760/cma.j.cn115989-20210922-00526 Published 2021-11-10 Cite asChin J Exp Ophthalmol, 2021, 39(11): 1021-1024. Abstract [View PDF] [Read Full Text] Age-related macular degeneration (AMD) is a disease caused by multiple factors such as age, genetics and environmental risks.Inflammation plays an important role […]
Breakdown of blood-retinal outer barrier in mice following acute high intraocular pressure
Authors: Li Wen, Cao Xing, Ye Changhua DOI: 10.3760/cma.j.cn115989-20200305-00146 Published 2021-10-10 Cite asChin J Exp Ophthalmol, 2021, 39(10): 852-856. Abstract [View PDF] [Read Full Text] Objective To investigate the breakdown of blood-retinal outer barrier in the ischemia-reperfusion injury mice following acute intraocular hypertension. Methods Fifty-seven […]
Physiological role and neuroprotective effects of somatostatin in retina
Authors: Zhang Yi, Sun Xinghuai, Wang Zhongfeng DOI: 10.3760/cma.j.cn115989-20191112-00492 Published 2021-10-10 Cite asChin J Exp Ophthalmol, 2021, 39(10): 915-918. Abstract [View PDF] [Read Full Text] Somatostatin, also called somatotropin release-inhibiting factor (SRIF), is a kind of neurotransmitter, neuromodulator and neurotrophic factor, which participates in a […]
Protective effect and mechanism of cx3cr1 antibody intravitreal injection in microcirculation of retinal ischemia-reperfusion injury in mice
Authors: Li Juanjuan, Chen Chen, Li Yan, Zhang Liwei DOI: 10.3760/cma.j.cn115989-20200104-00004 Published 2021-07-10 Cite asChin J Exp Ophthalmol, 2021, 39(7): 585-592. Abstract [View PDF] [Read Full Text] Objective To investigate the protective effect of C-X3-C motif chemokine receptor 1 (cx3cr1) antibody, a microglia activation inhibitor, […]
Specialized proresolving lipid mediators and eye diseases
Authors: Zhu Yingting, Li Yiqing, Zhuo Yehong DOI: 10.3760/cma.j.cn115989-20200607-00402 Published 2021-07-10 Cite asChin J Exp Ophthalmol, 2021, 39(7): 649-654. Abstract [View PDF] [Read Full Text] Novel endogenous lipid-mediated molecules including lipoxins, resolvins, protectins, and maresin families are discovered recently and are collectively called specialized proresolving […]
Warburg effect of retinal energetic metabolism and its regulatory mechanism
Authors: Han Guoge, Xing Yiqiao DOI: 10.3760/cma.j.cn115989-20200717-00505 Published 2021-07-10 Cite asChin J Exp Ophthalmol, 2021, 39(7): 655-660. Abstract [View PDF] [Read Full Text] Retinal metabolism includes material metabolism and energetic metabolism.Retina is one of the most energy-consuming nerve tissue in human body and mainly relies […]
Inhibiting effect of retinal Sigma-1 receptor antagonist on the form deprivation myopia in guinea pigs and its mechanism
Authors: Chen Yuanyuan, Xie Fujuan, Li Haibo, Guan Yuxin, Mao Junfeng DOI: 10.3760/cma.j.cn115989-20200615-00433 Published 2021-06-10 Cite asChin J Exp Ophthalmol, 2021, 39(6): 477-482. Abstract [View PDF] [Read Full Text] Objective To investigate the role and mechanism of retinal Sigma-1 receptor antagonist N, N-diethyl-2-[4-methoxy-3-(2-phenylethoxy)phenyl]ethanaminehydrochloride (NE-100) in […]
Paying close attention to the impact of cataract phacoemulsification surgery on ocular tissue
Author: Guan Huaijin DOI: 10.3760/cma.j.cn115989-20200424-00283 Published 2021-04-10 Cite asChin J Exp Ophthalmol, 2021, 39(4): 273-279. Abstract [View PDF] [Read Full Text] Although phacoemulsification is quite minimally invasive, effective and safe, it can still injure the structure of eyes and cause and/or aggravate […]