Tag: animal

Effect of integrin ανβ3 on conjunctival scar formation after glaucoma filtration surgery in rats

Authors: Zhu Xiaoyan,  Xie Lin,  Tan Wei DOI: 10.3760/cma.j.cn115989-20190917-00398 Published 2021-12-10 Cite asChin J Exp Ophthalmol, 2021, 39(12): 1046-1052. Abstract                              [View PDF] [Read Full Text] Objective To investigate the expression of integrin ανβ3 in conjunctival scar after glaucoma filtration surgery and to explore its role […]

Changes in DNA methylation of retinal gene promoter regions and their significance in type 1 diabetic rats

Authors: Li Yahong,  Geng Chao,  Liu Shengnan,  Wang Qi,  Li Xiaorong,  Zhang Yan DOI: 10.3760/cma.j.cn115985-20190616-00262 Published 2020-04-10 Cite as Chin J Exp Ophthalmol, 2020,38(04): 291-299. Abstract                              [View PDF] [Read Full Text] Objective To study the methylation level of retinal gene promoter region […]

Expression changes of brain-derived neurotrophic factor in retina of oxygen-induced retinopathy

Authors: Duan Haixia,  Guo Kai,  Wang Banwei DOI: 10.3760/cma.j.issn.2095-0160.2016.01.011 Published 2016-01-10 Cite as Chin J Exp Ophthalmol, 2016,34(1): 56-59. Abstract                              [Download PDF] [Read Full Text] Background Neovascular diseases such as retinopathy of prematurity often leads to irreversible vision loss.The study on oxidative damage mechanism is becoming more and […]

Dysfunction of tear film and ultrastructural changes of corneal epithelial cells in castrated male mice

Authors: Li Li,  Wang Shuangmei,  Zheng Xuan,  Kang Qianyan DOI: 10.3760/cma.j.issn.2095-0160.2016.02.002 Published 2016-02-10 Cite as Chin J Exp Ophthalmol, 2016,34(2): 103-107. Abstract                            [Download PDF] [Read Full Text] Background Studies indicate that the decline of androgen level affects the secretion function of epithelial cells of meibomian glands and lacrimal glands, which […]

Protective effects of thymosin β4 on ethanol-induced rabbit corneal epithelial cell damage in vitro

Authors: Jiang Zhixin,  Hao Peng,  Tang Xin,  Li Xuan DOI: 10.3760/cma.j.issn.2095-0160.2016.02.003 Published 2016-02-10 Cite as Chin J Exp Ophthalmol, 2016,34(2): 108-114. Abstract                              [Download PDF] [Read Full Text] Background Laser assisted subepithelial keratomileusis (LASEK) is one of surgical procedures for refractive correction. Dilute alcohol that is used for the removal […]

Pathogenesis and treatment of overwhelming inflammation induced by Pseudomonas aeruginosa keratitis in rabbit

Authors: Liang Qingfeng,  Li Bin,  Zhang Yang,  Labbe Antoine DOI: 10.3760/cma.j.issn.2095-0160.2016.02.007 Published 2016-02-10 Cite as Chin J Exp Ophthalmol, 2016,34(2): 125-131. Abstract                            [Download PDF] [Read Full Text] Background Infectious keratitis is common blinding eye disease in China. Inflammatory runaway reaction often occurs in infectious keratitis, and its mechanism and treating […]

Isolation and culture of corneal neovascular endothelial cells and expression of chemokine receptors

Authors: Liu Gaoqin,  Xiao Yanhui,  Chen Zhigang,  Xu Jing,  Lu Peirong DOI: 10.3760/cma.j.issn.2095-0160.2016.02.008 Published 2016-02-10 Cite as Chin J Exp Ophthalmol, 2016,34(2): 132-136. Abstract                            [Download PDF] [Read Full Text] Background The pathogenesis and mechanism research of corneal neovascularization is of important significance for the prevention and management of corneal neovascularization. Some […]

Application of zebrafish in ophthalmology and vision research: history and current progress

Authors: Chen Xueli,  Jing Yang,  Zhang Qi DOI: 10.3760/cma.j.issn.2095-0160.2016.04.017 Published 2016-04-10 Cite as Chin J Exp Ophthalmol, 2016,34(4): 368-370. Abstract                            [Download PDF] [Read Full Text] In recent years, zebrafish has become ideal animal models of human disease with its unique characteristics, such as small body, fecundity, fast […]

Suppressing effect of p21WAF1/CIP1 on traumatic proliferative vitreoretinopathy in rabbits

Authors: Yuan Zhigang,  You Caiyun,  Han Jindong,  Li Haiyan,  Yan Hua DOI: 10.3760/cma.j.issn.2095-0160.2016.05.008 Published 2016-05-10 Cite as Chin J Exp Ophthalmol, 2016,34(5): 420-425. Abstract                              [Download PDF] [Read Full Text] Background p21 is a cyclin-dependent kinase inhibitor, and it can prevent cells from going through the G1/S […]